The deficiency of miR-214-3p exacerbates cardiac fibrosis via miR-214-3p/NLRC5 axis

Metazoan MicroRNAs

(2018) David P. Bartel   CELL

NLRC5 silencing ameliorates cardiac fibrosis by inhibiting the TGF-β1/Smad3 signaling pathway

(2017) Hongtao Zhou et al.   Molecular Medicine Reports

MicroRNA-214 exerts a Cardio-protective effect by inhibition of fibrosis

(2016) Hua Dong et al.   Anatomical Record-Advances in Integrative Anatomy and Evolutionary Biology

Glutamine protects cardiomyocytes from hypoxia/reoxygenation injury under high glucose conditions through inhibition of the transforming growth factor-β1-Smad3 pathway

(2016) Hong Zhang et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Silencing NLRC5 inhibits extracellular matrix expression in keloid fibroblasts via inhibition of transforming growth factor-β1/Smad signaling pathway

(2016) Hai-Li Ma et al.   BIOMEDICINE & PHARMACOTHERAPY

NLRC5 regulates TGF-β1-induced proliferation and activation of hepatic stellate cells during hepatic fibrosis

(2016) Tao Xu et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Targeting EZH1 and EZH2 contributes to the suppression of fibrosis-associated genes by miR-214-3p in cardiac myofibroblasts

(2016) Wen-Si Zhu et al.   Oncotarget

MiR-125b is Critical for Fibroblast-to-Myofibroblast Transition and Cardiac Fibrosis

(2015) Varun Nagpal et al.   CIRCULATION

lncRNA-MIAT Regulates Microvascular Dysfunction by Functioning as a Competing Endogenous RNANovelty and Significance

(2015) Biao Yan et al.   CIRCULATION RESEARCH

MicroRNA-214 Is Upregulated in Heart Failure Patients and Suppresses XBP1-Mediated Endothelial Cells Angiogenesis

(2015) Quanlu Duan et al.   JOURNAL OF CELLULAR PHYSIOLOGY

MicroRNA-214 Mediates Isoproterenol-induced Proliferation and Collagen Synthesis in Cardiac Fibroblasts

(2015) Min Sun et al.   Scientific Reports

The microRNA-15 family inhibits the TGFβ-pathway in the heart

(2014) Anke J. Tijsen et al.   CARDIOVASCULAR RESEARCH

Mesenchymal–endothelial transition contributes to cardiac neovascularization

(2014) Eric Ubil et al.   NATURE

The pathogenesis of cardiac fibrosis

(2013) Ping Kong et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Extracellular Matrix Secretion by Cardiac Fibroblasts

(2013) Mélanie Abonnenc et al.   CIRCULATION RESEARCH

The Structure of Human Argonaute-2 in Complex with miR-20a

(2012) Elad Elkayam et al.   CELL

Transcriptional targeting by microRNA-Polycomb complexes: A novel route in cell fate determination

(2012) Giuseppe Zardo et al.   CELL CYCLE

Cardiotoxic and Cardioprotective Features of Chronic β-Adrenergic Signaling

(2012) Xiaoying Zhang et al.   CIRCULATION RESEARCH

MicroRNA-214 protects the mouse heart from ischemic injury by controlling Ca2+ overload and cell death

(2012) Arin B. Aurora et al.   JOURNAL OF CLINICAL INVESTIGATION

MicroRNAs, transforming growth factor beta-1, and tissue fibrosis

(2012) Timothy Bowen et al.   JOURNAL OF PATHOLOGY

Myofibroblast-mediated mechanisms of pathological remodelling of the heart

(2012) Karl T. Weber et al.   Nature Reviews Cardiology

Metformin attenuates cardiac fibrosis by inhibiting the TGFβ1–Smad3 signalling pathway

(2010) Han Xiao et al.   CARDIOVASCULAR RESEARCH

Origins of Cardiac Fibroblasts

(2010) Elisabeth M. Zeisberg et al.   CIRCULATION RESEARCH

Origins and Mechanisms of miRNAs and siRNAs

(2009) Richard W. Carthew et al.   CELL