CRISPR-Cas12 and Cas13: the lesser known siblings of CRISPR-Cas9

Off-target challenge for base editor-mediated genome editing

(2019) Puping Liang et al.   CELL BIOLOGY AND TOXICOLOGY

Off-target genome editing: A new discipline of gene science and a new class of medicine

(2019) Diane Catherine Wang et al.   CELL BIOLOGY AND TOXICOLOGY

Refining CRISPR-based genome and epigenome editing off-targets

(2019) Yonglun Luo   CELL BIOLOGY AND TOXICOLOGY

Keeping our eyes on CRISPR: the “Atlas” of gene editing

(2019) William Wang et al.   CELL BIOLOGY AND TOXICOLOGY

Battling CRISPR-Cas9 off-target genome editing

(2019) Daisy Li et al.   CELL BIOLOGY AND TOXICOLOGY

Minimizing off-target effects in CRISPR-Cas9 genome editing

(2019) Shi-Jie Chen   CELL BIOLOGY AND TOXICOLOGY

Transcriptome Engineering with RNA-Targeting Type VI-D CRISPR Effectors

(2018) Silvana Konermann et al.   CELL

CRISPR-Cas12a target binding unleashes indiscriminate single-stranded DNase activity

(2018) Janice S. Chen et al.   SCIENCE

Multiplexed and portable nucleic acid detection platform with Cas13, Cas12a, and Csm6

(2018) Jonathan S. Gootenberg et al.   SCIENCE

Functionally diverse type V CRISPR-Cas systems

(2018) Winston X. Yan et al.   SCIENCE

Structural Basis for Guide RNA Processing and Seed-Dependent DNA Targeting by CRISPR-Cas12a

(2017) Daan C. Swarts et al.   MOLECULAR CELL

Nucleic acid detection with CRISPR-Cas13a/C2c2

(2017) Jonathan S. Gootenberg et al.   SCIENCE

The CRISPR Spacer Space Is Dominated by Sequences from Species-Specific Mobilomes

(2017) Sergey A. Shmakov et al.   mBio

Crystal Structure of Cpf1 in Complex with Guide RNA and Target DNA

(2016) Takashi Yamano et al.   CELL

Could CRISPR be the solution for gene editing’s Gordian knot?

(2016) Hao Fang et al.   CELL BIOLOGY AND TOXICOLOGY

C2c2 is a single-component programmable RNA-guided RNA-targeting CRISPR effector

(2016) Omar O. Abudayyeh et al.   SCIENCE