Review
Medicine, General & Internal
Andrej Wagner, Stephan Zandanell, Tobias Kiesslich, Daniel Neureiter, Eckhard Klieser, Josef Holzinger, Frieder Berr
Summary: Endoscopic characterization of gastrointestinal neoplasias using image-enhanced and magnification endoscopy shows diagnostic accuracy over 90%, but further prospective clinical studies are needed for validation in various types of neoplasms.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Gastroenterology & Hepatology
Nobuhito Ito, Kohei Funasaka, Toshihisa Fujiyoshi, Kazuki Nishida, Kazuhiro Furukawa, Naomi Kakushima, Satoshi Furune, Eizaburo Ohno, Masanao Nakamura, Noriyuki Horiguchi, Tomoyuki Shibata, Ryoji Miyahara, Jun-Ichi Haruta, Yoshiki Hirooka, Mitsuhiro Fujishiro, Hiroki Kawashima
Summary: This study aimed to develop a scoring system to predict the long-term prognosis after endoscopic submucosal dissection (ESD) for early gastric cancer (EGC) among patients aged >= 75 years. Factors such as Charlson comorbidity index (CCI), psoas muscle index (PMI), and age were identified to be significantly related to overall survival after ESD. The scoring system, which included high CCI, low PMI, and age >= 80 years, successfully stratified the long-term prognosis of elderly patients after ESD.
DIGESTIVE ENDOSCOPY
(2023)
Review
Gastroenterology & Hepatology
Katsuhiro Mabe, Kazuhiko Inoue, Tomoari Kamada, Katsuaki Kato, Mototsugu Kato, Ken Haruma
Summary: The revised 2014 Japanese Guidelines for Gastric Cancer Screening approved the use of gastric endoscopy for population-based screening, aiming to detect gastric cancer earlier and decrease mortality rates with the widespread use of endoscopy and Helicobacter pylori eradication therapy. Despite the era of endoscopic gastric cancer screening beginning, challenges remain due to limited/varying regional availability of endoscopists, and gastric cancer continues to be the leading cause of cancer death in Japan. efforts are being made to improve screening by stratifying individuals according to their risk of gastric cancer.
DIGESTIVE ENDOSCOPY
(2022)
Article
Multidisciplinary Sciences
Joshua J. Yim, Stefan Harmsen, Krzysztof Flisikowski, Tatiana Flisikowska, Hong Namkoong, Megan Garland, Nynke S. van den Berg, Jose G. Vilches-Moure, Angelika Schnieke, Dieter Saur, Sarah Glasl, Dimitris Gorpas, Aida Habtezion, Vasilis Ntziachristos, Christopher H. Contag, Sanjiv S. Gambhir, Matthew Bogyo, Stephan Rogalla
Summary: Fluorescently labeled probes show great potential for clinical application in highlighting gastrointestinal lesions, providing fluorescence-guided surveillance and enhancing histopathological analysis by highlighting areas of dysplasia as small as 400 microns, even in tissues with severe inflammation and ulceration.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2021)
Article
Surgery
Byunghyuk Yu, Ki Bum Park, Ji Yeon Park, Seung Soo Lee, Oh Kyoung Kwon, Ho Young Chung, Yoon Jin Hwang
Summary: This study compared the clinical outcomes of different reconstruction methods after laparoscopic proximal gastrectomy, including quality of life and changes in body composition. The results showed that performing double flap technique (DFT) after the surgery resulted in better 1-year quality of life and nutritional outcomes.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2022)
Article
Gastroenterology & Hepatology
Masaya Iwamuro, Toshiharu Mitsuhashi, Tomoki Inaba, Kazuhiro Matsueda, Teruya Nagahara, Yoji Takeuchi, Hisashi Doyama, Masakatsu Mizuno, Tomoyuki Yada, Yoshinari Kawai, Jun Nakamura, Minoru Matsubara, Hiroko Nebiki, Keiko Niimi, Tatsuya Toyokawa, Ryuta Takenaka, Sho Takeda, Shouichi Tanaka, Mamoru Nishimura, Takao Tsuzuki, Kazuya Akahoshi, Takahisa Furuta, Ken Haruma, Hiroyuki Okada
Summary: To investigate the long-term outcomes of gastric subepithelial lesions, a prospective observational study with a 10-year follow-up was conducted. The interim analysis revealed that approximately one in 13 patients with small (<= 20 mm) gastric subepithelial lesions may require resection or further investigation for increased tumor size (>= 5 mm) within 5 years.
DIGESTIVE ENDOSCOPY
(2023)
Article
Gastroenterology & Hepatology
Yoshitaka Tokai, Yusuke Horiuchi, Noriko Yamamoto, Ken Namikawa, Shoichi Yoshimizu, Akiyoshi Ishiyama, Toshiyuki Yoshio, Toshiaki Hirasawa, Junko Fujisaki
Summary: This study aimed to investigate the effect of Helicobacter pylori eradication therapy on mixed-histological-type early gastric cancer. The results showed that eradication of Helicobacter pylori can affect the pathological findings of differentiated-type gastric cancer, but does not affect the diagnosis of differentiated-type gastric cancer using magnifying endoscopy with narrow-band imaging.
BMC GASTROENTEROLOGY
(2023)
Article
Oncology
Ji Eun Ryu, Eunji Choi, Kyeongmin Lee, Jae Kwan Jun, Mina Suh, Kyu Won Jung, Kui Son Choi
Summary: The Korean National Cancer Screening Program has implemented two screening methods for gastric cancer: upper gastrointestinal series and endoscopy. The use of endoscopy for gastric cancer screening has increased, and it has higher cancer detection rates, sensitivity, and specificity compared to upper gastrointestinal series.
CANCER RESEARCH AND TREATMENT
(2022)
Article
Oncology
Seong-Ho Kong, Yukinori Kurokawa, Jeong-Hwan Yook, Haruhiko Cho, Oh-Kyoung Kwon, Toru Masuzawa, Kyung Hee Lee, Sohei Matsumoto, Young Soo Park, Hiroshi Honda, Seung-Wan Ryu, Takashi Ishikawa, Hye Jin Kang, Kazuhito Nabeshima, Seock-Ah Im, Toshio Shimokawa, Yoon-Koo Kang, Seiichi Hirota, Han-Kwang Yang, Toshirou Nishida
Summary: This study confirms that neoadjuvant imatinib treatment is an effective option for gastric GISTs. It reduces tumor size and increases the rate of R0 resection. Postoperative imatinib treatment is recommended to minimize the risk of recurrence.
Article
Biochemistry & Molecular Biology
Javeria Naz, Muhammad Imran Sharif, Muhammad Irfan Sharif, Seifedine Kadry, Hafiz Tayyab Rauf, Adham E. Ragab
Summary: Esophagitis, cancerous growths, bleeding, and ulcers are common symptoms of gastrointestinal disorders that contribute to high human mortality. This research proposes a hybrid method for accurate diagnosis and early treatment of gastrointestinal abnormalities. The method involves dataset augmentation, preprocessing, feature engineering, and classification, with image enhancement and deep learning techniques used. The proposed method achieved superior accuracy compared to recent methods on two datasets, with Q_SVM accuracies of 100% and 99.24% on the Hybrid dataset and Kvasir-V1 dataset, respectively.
Article
Oncology
Song Liu, Mengying Xu, Xiangmei Qiao, Changfeng Ji, Lin Li, Zhengyang Zhou
Summary: The study developed multivariate models to predict serosal invasion in gastric cancer by integrating endoscopic biopsy, tumor markers, CT morphological characteristics, and CT value-related texture parameters. The multivariate models achieved favorable diagnostic efficacy based on regression analysis and machine learning algorithms, showing significant discriminative ability in the primary cohort.
Review
Gastroenterology & Hepatology
Gwang Ha Kim
Summary: Early gastric cancers (EGCs) are defined as gastric cancers confined to the mucosa or submucosa, regardless of regional lymph node metastasis. The shift from surgical resection to endoscopic resection for selected EGCs is accelerating due to increased screening endoscopy. Successful endoscopic resection of EGCs requires early detection and accurate prediction of histological type, depth of invasion, and horizontal margins.
Review
Oncology
Teresa Da Cunha, David Restrepo, Simon Abi-Saleh, Murali Dharan
Summary: The exact incidence of breast cancer metastasis to the upper gastrointestinal tract is not well established, and clinical presentation is often non-specific, leading to misdiagnosis. High awareness and clinical suspicion are required for the diagnosis of upper gastrointestinal tract metastases.
WORLD JOURNAL OF GASTROINTESTINAL ONCOLOGY
(2023)
Article
Gastroenterology & Hepatology
Anne F. Peery, Seth D. Crockett, Caitlin C. Murphy, Elizabeth T. Jensen, Hannah P. Kim, Matthew D. Egberg, Jennifer L. Lund, Andrew M. Moon, Virginia Pate, Edward L. Barnes, Courtney L. Schlusser, Todd H. Baron, Nicholas J. Shaheen, Robert S. Sandler
Summary: Gastrointestinal diseases in the United States result in significant healthcare utilization and expenditures, with millions of healthcare encounters and hundreds of thousands of deaths each year. To address this burden, focused clinical and public health efforts, along with increased research funding, are necessary.
Article
Surgery
So Hyun Kang, Mira Yoo, Duyeong Hwang, Eunju Lee, Sangjun Lee, Young Suk Park, Sang-Hoon Ahn, Yun-Suhk Suh, Hyung-Ho Kim
Summary: This study compared the postoperative outcomes and patient quality of life between single-incision distal gastrectomy (SIDG) and multiport laparoscopic distal gastrectomy (MLDG). The results showed no significant difference in postoperative pain scores, hospital stay, and postoperative QOL between the two groups.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2023)
Article
Endocrinology & Metabolism
R. B. T. Lim, C. Chen, N. Naidoo, G. Gay, W. E. Tang, D. Seah, R. Chen, N. C. Tan, J. Lee, E. S. Tai, K. S. Chia, W. Y. Lim
DIABETES & METABOLISM
(2015)
Article
Medical Laboratory Technology
Dineo V. Phatlhane, Annalise E. Zemlin, Tandi E. Matsha, Mariza Hoffmann, Nasheen Naidoo, Kitoshi Ichihara, Francois Smit, Rajiv T. Erasmus
CLINICA CHIMICA ACTA
(2016)
Article
Cardiac & Cardiovascular Systems
Agus Salim, E. Shyong Tai, Vincent Y. Tan, Alan H. Welsh, Reginald Liew, Nasheen Naidoo, Yi Wu, Jian-Min Yuan, Woon P. Koh, Rob M. van Dam
EUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY
(2016)
Article
Nutrition & Dietetics
Nasheen Naidoo, Rob M. van Dam, Sheryl Ng, Chuen Seng Tan, Shiqi Chen, Jia Yi Lim, Mei Fen Chan, Ling Chew, Salome A. Rebello
INTERNATIONAL JOURNAL OF BEHAVIORAL NUTRITION AND PHYSICAL ACTIVITY
(2017)
Review
Medical Laboratory Technology
Ravnit Grewal, Alexandra Irimie, Nasheen Naidoo, Nooroudien Mohamed, Bobe Petrushev, Manogari Chetty, Ciprian Tomuleasa, Emmanuel-Akinola Abayomi
CRITICAL REVIEWS IN CLINICAL LABORATORY SCIENCES
(2018)
Article
Medicine, General & Internal
N. Naidoo, A. Abayomi, C. Locketz, F. Musaigwa, R. Grewal
SAMJ SOUTH AFRICAN MEDICAL JOURNAL
(2018)
Article
Nutrition & Dietetics
Salome A. Rebello, Hiromi Koh, Cynthia Chen, Nasheen Naidoo, Andrew O. Odegaard, Woon-Puay Koh, Lesley M. Butler, Jian-Min Yuan, Rob M. van Dam
AMERICAN JOURNAL OF CLINICAL NUTRITION
(2014)
Article
Nutrition & Dietetics
May C. Wang, Nasheen Naidoo, Steve Ferzacca, Geetha Reddy, Rob M. Van Dam
ECOLOGY OF FOOD AND NUTRITION
(2014)
Article
Ethics
Sibusiso Sifunda, Priscilla Reddy, Nasheen Naidoo, Shamagonam James, David Buchanan
PUBLIC HEALTH ETHICS
(2014)
Article
Public, Environmental & Occupational Health
Hui Jun Zhou, Jing Cao, Hui Shi, Nasheen Naidoo, Sherehe Semba, Pei Wang, Yi Fan Fan, Shui Cheng Zhu
Summary: The study identified SOF/LDV as the most cost-effective treatment for HCV genotype 1, producing more QALYs at a lower cost compared to SOF/VEL and the traditional pegIFN + RBV regimen. SOF/VEL was also economically dominant to pegIFN + RBV, suggesting DAA regimens could be a promising strategy for treating HCV.
FRONTIERS IN PUBLIC HEALTH
(2021)
Article
Health Care Sciences & Services
Hui-Jun Zhou, Gang Wu, Ji-Ming Li, Nasheen Naidoo, Yan-Xiang Xie, Bo-Lan Feng, Pei Wang, Ji-Wei Luo
Summary: The study evaluated the cost-effectiveness of glecaprevir/pibrentasvir (GLE/PIB) for chronic HCV genotype 1 and genotype 2 infection in China, finding that GLE/PIB was a cost-saving regimen with increased quality-adjusted life years compared to the pegylated interferon (pegIFN) plus ribavirin (RBV). The probability of GLE/PIB being cost-effective was high, especially for HCV genotype 1 infection. Influential factors included age of starting DAA treatment, price of pegIFN + RBV, cost of cirrhosis treatment, and duration of the GLE/PIB regimen.
ANNALS OF PALLIATIVE MEDICINE
(2021)
Article
Medicine, Research & Experimental
Kamela L. Mahlakwane, Wolfgang Preiser, Nokwazi Nkosi, Nasheen Naidoo, Gert van Zyl
Summary: This study assessed the metrics of routine infant HIV PCR testing at a hospital in South Africa and found a high proportion of rejected test requests and a need for shorter turn-around time for confirmatory testing.
AFRICAN JOURNAL OF LABORATORY MEDICINE
(2022)
Article
Public, Environmental & Occupational Health
Xiaoyan Liu, Huijun Zhou, Jie Wei, Minghui Li, Guofen Luo, Nasheen Naidoo, Guang Zhang, Ye Bi, Mengmeng Gao
Summary: This study examined the health utility and occupational diseases among university staff in China. The findings indicate that psychological conditions and musculoskeletal pain are major concerns. These results provide valuable information for cost-utility analysis and the implementation of cost-effective programs.
FRONTIERS IN PUBLIC HEALTH
(2023)
Article
Medicine, General & Internal
N. Naidoo, R. T. Erasmus, R. Grewal, A. E. Zemlin
SAMJ SOUTH AFRICAN MEDICAL JOURNAL
(2017)