Immune Regulation in Eutherian Pregnancy: Live Birth Coevolved with Novel Immune Genes and Gene Regulation

Comparative analysis of mouse and human placentae across gestation reveals species-specific regulators of placental development

(2018) Francesca Soncin et al.   DEVELOPMENT

Identification of Transposable Elements Contributing to Tissue-Specific Expression of Long Non-Coding RNAs

(2018) Takafumi Chishima et al.   Genes

The mammalian decidual cell evolved from a cellular stress response

(2018) Eric M. Erkenbrack et al.   PLOS BIOLOGY

Anthropoid primate–specific retroviral element THE1B controls expression of CRH in placenta and alters gestation length

(2018) Caitlin E. Dunn-Fletcher et al.   PLOS BIOLOGY

Maternal and fetal intrauterine tissue crosstalk promotes pro-inflammatory amplification and uterine transition.

(2018) Kelycia B Leimert et al.   BIOLOGY OF REPRODUCTION

Embryo implantation evolved from an ancestral inflammatory attachment reaction

(2017) Oliver W. Griffith et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

HEMO, an ancestral endogenous retroviral envelope protein shed in the blood of pregnant women and expressed in pluripotent stem cells and tumors

(2017) Odile Heidmann et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A pronounced uterine pro-inflammatory response at parturition is an ancient feature in mammals

(2017) Victoria L. Hansen et al.   PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Novel and divergent genes in the evolution of placental mammals

(2017) Thomas L. Dunwell et al.   PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

The SIGLEC14 null allele is associated with Mycobacterium tuberculosis- and BCG-induced clinical and immunologic outcomes

(2017) Andrew D. Graustein et al.   TUBERCULOSIS

The placenta as a model for understanding the origin and evolution of vertebrate organs

(2017) Oliver W. Griffith et al.   Nature Ecology & Evolution

The Transcriptomic Evolution of Mammalian Pregnancy: Gene Expression Innovations in Endometrial Stromal Fibroblasts

(2016) Koryu Kin et al.   Genome Biology and Evolution

A distant trophoblast-specific enhancer controls HLA-G expression at the maternal–fetal interface

(2016) Leonardo M. R. Ferreira et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pregnancy disorders in Africa and the obstetric dilemma

(2016) Annettee Nakimuli et al.   TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE

Decidual natural killer cells regulate vessel stability: implications for impaired spiral artery remodelling

(2015) Rupsha Fraser et al.   JOURNAL OF REPRODUCTIVE IMMUNOLOGY

AKIR Bcentromeric region present in Africans but not Europeans protects pregnant women from pre-eclampsia

(2015) Annettee Nakimuli et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ancient Transposable Elements Transformed the Uterine Regulatory Landscape and Transcriptome during the Evolution of Mammalian Pregnancy

(2015) Vincent J. Lynch et al.   Cell Reports

The Placental Protein Syncytin-1 Impairs Antiviral Responses and Exaggerates Inflammatory Responses to Influenza

(2015) Jorge M. Tolosa et al.   PLoS One

Uterine NK cells: active regulators at the maternal-fetal interface

(2014) Ashley Moffett et al.   JOURNAL OF CLINICAL INVESTIGATION

Siglec-5 and Siglec-14 are polymorphic paired receptors that modulate neutrophil and amnion signaling responses to group BStreptococcus

(2014) Syed Raza Ali et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Loss of Siglec-14 reduces the risk of chronic obstructive pulmonary disease exacerbation

(2013) Takashi Angata et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Killer cell immunoglobulin-like receptor (KIR) genes and their HLA-C ligands in a Ugandan population

(2013) Annettee Nakimuli et al.   IMMUNOGENETICS

Maternal uterine NK cell–activating receptor KIR2DS1 enhances placentation

(2013) Shiqiu Xiong et al.   JOURNAL OF CLINICAL INVESTIGATION

Paleovirology of 'syncytins', retroviral env genes exapted for a role in placentation

(2013) C. Lavialle et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Widespread Divergence of the CEACAM/PSG Genes in Vertebrates and Humans Suggests Sensitivity to Selection

(2013) Chia Lin Chang et al.   PLoS One

Early Expression of Pregnancy-Specific Glycoprotein 22 (PSG22) by Trophoblast Cells Modulates Angiogenesis in Mice1

(2012) Sandra M. Blois et al.   BIOLOGY OF REPRODUCTION

Pregnancy-specific glycoprotein 1a activates dendritic cells to provide signals for Th17-, Th2-, and Treg-cell polarization

(2012) Fernando F. Martínez et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Galectin-1 influences trophoblast immune evasion and emerges as a predictive factor for the outcome of pregnancy

(2012) I. Tirado-Gonzalez et al.   MOLECULAR HUMAN REPRODUCTION

Inflammation and pregnancy: the role of the immune system at the implantation site

(2011) Gil Mor et al.   Annals of the New York Academy of Sciences

The effect of pregnancy on the uterine NK cell KIR repertoire

(2011) Victoria Male et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Macrophages at the Fetal-Maternal Interface Express Markers of Alternative Activation and Are Induced by M-CSF and IL-10

(2011) J. Svensson et al.   JOURNAL OF IMMUNOLOGY

Galectin-1 Binds to Influenza Virus and Ameliorates Influenza Virus Pathogenesis

(2011) M.-L. Yang et al.   JOURNAL OF VIROLOGY

Hypomethylation of functional retrotransposon-derived genes in the human placenta

(2011) Erin C. Macaulay et al.   MAMMALIAN GENOME

Transposon-mediated rewiring of gene regulatory networks contributed to the evolution of pregnancy in mammals

(2011) Vincent J Lynch et al.   NATURE GENETICS

Coevolution of activating and inhibitory receptors within mammalian carcinoembryonic antigen families

(2010) Robert Kammerer et al.   BMC BIOLOGY

Association of KIR2DS1 and KIR2DS3 with fatal outcome in Ebola virus infection

(2010) Nadia Wauquier et al.   IMMUNOGENETICS

Maternal activating KIRs protect against human reproductive failure mediated by fetal HLA-C2

(2010) Susan E. Hiby et al.   JOURNAL OF CLINICAL INVESTIGATION

Gene regulation and the origins of human biological uniqueness

(2010) Samuel J. Sholtis et al.   TRENDS IN GENETICS

Human-Specific Evolution and Adaptation Led to Major Qualitative Differences in the Variable Receptors of Human and Chimpanzee Natural Killer Cells

(2010) Laurent Abi-Rached et al.   PLoS Genetics

Genome-Wide Identification of Susceptibility Alleles for Viral Infections through a Population Genetics Approach

(2010) Matteo Fumagalli et al.   PLoS Genetics

Deletion polymorphism of SIGLEC14 and its functional implications

(2009) M. Yamanaka et al.   GLYCOBIOLOGY

Comparative genomics indicates the mammalian CD33rSiglec locus evolved by an ancient large-scale inverse duplication and suggests all Siglecs share a common ancestral region

(2009) Huan Cao et al.   IMMUNOGENETICS

A Caenorhabditis elegans Glycolipid-binding Galectin Functions in Host Defense against Bacterial Infection

(2009) Hiroko Ideo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Small, Variable, and Irregular Killer Cell Ig-Like Receptor Locus Accompanies the Absence of MHC-C and MHC-G in Gibbons

(2009) L. Abi-Rached et al.   JOURNAL OF IMMUNOLOGY

Syncytin-2 Plays an Important Role in the Fusion of Human Trophoblast Cells

(2009) Amandine Vargas et al.   JOURNAL OF MOLECULAR BIOLOGY

Syncytin-A knockout mice demonstrate the critical role in placentation of a fusogenic, endogenous retrovirus-derived, envelope gene

(2009) A. Dupressoir et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A primate subfamily of galectins expressed at the maternal-fetal interface that promote immune cell death

(2009) N. G. Than et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Evolution, Regulation, and Function of Placenta-Specific Genes

(2008) Saara M. Rawn et al.   Annual Review of Cell and Developmental Biology

Functional Characterization of the Human Placental Fusogenic Membrane Protein Syncytin 21

(2008) Chie-Pein Chen et al.   BIOLOGY OF REPRODUCTION

Genomic evolution of the placenta using co-option and duplication and divergence

(2008) K. Knox et al.   GENOME RESEARCH

T cell apoptosis at the maternal-fetal interface in early human pregnancy, involvement of galectin-1

(2008) H. D. Kopcow et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA