MARK4 (Microtubule Affinity-Regulating Kinase 4)-Dependent Inflammasome Activation Promotes Atherosclerosis—Brief Report

Targeting the Immune System in Atherosclerosis

(2019) Tian X. Zhao et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Consideration of Sex Differences in Design and Reporting of Experimental Arterial Pathology Studies—Statement From ATVB CouncilHighlights

(2018) Peggy Robinet et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Double-Strand DNA Sensing Aim2 Inflammasome Regulates Atherosclerotic Plaque Vulnerability

(2018) Nicole Paulin et al.   CIRCULATION

Antiinflammatory Therapy with Canakinumab for Atherosclerotic Disease

(2017) Paul M Ridker et al.   NEW ENGLAND JOURNAL OF MEDICINE

MARK4 regulates NLRP3 positioning and inflammasome activation through a microtubule-dependent mechanism

(2017) Xuan Li et al.   Nature Communications

Necrotic Cell Sensor Clec4e Promotes a Proatherogenic Macrophage Phenotype Through Activation of the Unfolded Protein ResponseClinical Perspective

(2016) Marc Clément et al.   CIRCULATION

Microtubule-associated protein/microtubule affinity-regulating kinase 4 (MARK4) plays a role in cell cycle progression and cytoskeletal dynamics

(2014) Davide Rovina et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Inactivation of MARK4, an AMP-activated Protein Kinase (AMPK)-related Kinase, Leads to Insulin Hypersensitivity and Resistance to Diet-induced Obesity

(2012) Chao Sun et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Atherosclerosis in ApoE-deficient mice progresses independently of the NLRP3 inflammasome

(2011) P Menu et al.   Cell Death & Disease

NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals

(2010) Peter Duewell et al.   NATURE

Cholesterol Crystals Activate the NLRP3 Inflammasome in Human Macrophages: A Novel Link between Cholesterol Metabolism and Inflammation

(2010) Kristiina Rajamäki et al.   PLoS One