Validation of Genome-Wide Polygenic Risk Scores for Coronary Artery Disease in French Canadians

Whole Genome Sequencing to Characterize Monogenic and Polygenic Contributions in Patients Hospitalized with Early-Onset Myocardial Infarction

(2019) Amit V. Khera et al.   CIRCULATION

The illusion of polygenic disease risk prediction

(2019) Nicholas J. Wald et al.   GENETICS IN MEDICINE

The personal and clinical utility of polygenic risk scores

(2018) Ali Torkamani et al.   NATURE REVIEWS GENETICS

Genome-wide polygenic scores for common diseases identify individuals with risk equivalent to monogenic mutations

(2018) Amit V. Khera et al.   NATURE GENETICS

Variants at the APOE/C1/C2/C4 Locus Modulate Cholesterol Efflux Capacity Independently of High‐Density Lipoprotein Cholesterol

(2018) Cécile Low‐Kam et al.   Journal of the American Heart Association

Genomic Risk Prediction of Coronary Artery Disease in 480,000 Adults

(2018) Michael Inouye et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Rare and low-frequency coding variants alter human adult height

(2017) Eirini Marouli et al.   NATURE

Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk

(2017) Helen R Warren et al.   NATURE GENETICS

Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease

(2017) Pim van der Harst et al.   CIRCULATION RESEARCH

Comparing distributions of polygenic risk scores of type 2 diabetes and coronary heart disease within different populations

(2017) Sulev Reisberg et al.   PLoS One

Genomic prediction of coronary heart disease

(2016) Gad Abraham et al.   EUROPEAN HEART JOURNAL

Whole-genome sequencing in French Canadians from Quebec

(2016) Cécile Low-Kam et al.   HUMAN GENETICS

Modeling Linkage Disequilibrium Increases Accuracy of Polygenic Risk Scores

(2015) Bjarni J. Vilhjálmsson et al.   AMERICAN JOURNAL OF HUMAN GENETICS

A comprehensive 1000 Genomes–based genome-wide association meta-analysis of coronary artery disease

(2015) Majid Nikpay et al.   NATURE GENETICS

Projecting the performance of risk prediction based on polygenic analyses of genome-wide association studies

(2013) Nilanjan Chatterjee et al.   NATURE GENETICS

Cohort profile of the CARTaGENE study: Quebec’s population-based biobank for public health and personalized genomics

(2012) Philip Awadalla et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Large-scale association analysis identifies new risk loci for coronary artery disease

(2012) Panos Deloukas et al.   NATURE GENETICS

Geographic distribution of French-Canadian low-density lipoprotein receptor gene mutations in the Province of Quebec

(2010) Marie-Claude Vohl et al.   CLINICAL GENETICS

Common SNPs explain a large proportion of the heritability for human height

(2010) Jian Yang et al.   NATURE GENETICS