Pathophysiology and therapy of myocardial ischaemia/reperfusion syndrome

Mitochondria "THE" target of myocardial conditioning

(2018) Kerstin Boengler et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Reflection of Cardioprotection by Remote Ischemic Perconditioning in Attenuated ST-Segment Elevation During Ongoing Coronary Occlusion in PigsNovelty and Significance

(2018) Petra Kleinbongard et al.   CIRCULATION RESEARCH

Infarct Size Reduction by Targeting Ischemic Injury

(2018) Xavier Rossello et al.   CIRCULATION RESEARCH

Take a deep (nitric oxide) breath and follow the reverse translational research pathway

(2018) Manuel Lobo et al.   EUROPEAN HEART JOURNAL

Nitric oxide for inhalation in ST-elevation myocardial infarction (NOMI): a multicentre, double-blind, randomized controlled trial

(2018) Stefan P Janssens et al.   EUROPEAN HEART JOURNAL

Novel insights into the role of mitochondrial fusion and fission in cardiomyocyte apoptosis induced by ischemia/reperfusion

(2018) YuZhen Li et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Impact of mineralocorticoid receptor antagonists on the risk of sudden cardiac death in patients with heart failure and left-ventricular systolic dysfunction: an individual patient-level meta-analysis of three randomized-controlled trials

(2018) Xavier Rossello et al.   Clinical Research in Cardiology

Improved outcomes in patients with ST-elevation myocardial infarction during the last 20 years are related to implementation of evidence-based treatments: experiences from the SWEDEHEART registry 1995–2014

(2017) Karolina Szummer et al.   EUROPEAN HEART JOURNAL

2017 ESC Guidelines for the management of acute myocardial infarction in patients presenting with ST-segment elevation

(2017) Borja Ibanez et al.   EUROPEAN HEART JOURNAL

A new era in the management of type 2 diabetes: Is cardioprotection at long last a reality?

(2017) Xavier Rossello et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Global geographical variations in ST-segment elevation myocardial infarction management and post-discharge mortality

(2017) Xavier Rosselló et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Impacto del territorio miocárdico infartado en la cuantificación del área en riesgo mediante cardiorresonancia magnética

(2017) Leticia Fernández-Friera et al.   REVISTA ESPANOLA DE CARDIOLOGIA

Neutrophil stunning by metoprolol reduces infarct size

(2017) Jaime García-Prieto et al.   Nature Communications

Effect of Ischemic Postconditioning During Primary Percutaneous Coronary Intervention for Patients With ST-Segment Elevation Myocardial Infarction

(2017) Thomas Engstrøm et al.   JAMA Cardiology

Ischaemic conditioning and targeting reperfusion injury: a 30 year voyage of discovery

(2016) Derek J. Hausenloy et al.   BASIC RESEARCH IN CARDIOLOGY

Cardioprotection

(2016) Xavier Rossello et al.   CIRCULATION

The Coronary Circulation as a Target of Cardioprotection

(2016) Gerd Heusch   CIRCULATION RESEARCH

Remote ischaemic conditioning and healthcare system delay in patients with ST-segment elevation myocardial infarction

(2016) Kasper Pryds et al.   HEART

A critical review on the translational journey of cardioprotective therapies!

(2016) Xavier Rossello et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Clinical benefit of adenosine as an adjunct to reperfusion in ST-elevation myocardial infarction patients: An updated meta-analysis of randomized controlled trials

(2016) Heerajnarain Bulluck et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Relationship Between Infarct Size and Outcomes Following Primary PCI

(2016) Gregg W. Stone et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Early Intravenous Beta-Blockers in Patients With ST-Segment Elevation Myocardial Infarction Before Primary Percutaneous Coronary Intervention

(2016) Vincent Roolvink et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Impact of the Timing of Metoprolol Administration During STEMI on Infarct Size and Ventricular Function

(2016) Jose M. García-Ruiz et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Cyclosporine A in Reperfused Myocardial Infarction

(2016) Filippo Ottani et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Diagnostic Ultrasound Impulses Improve Microvascular Flow in Patients With STEMI Receiving Intravenous Microbubbles

(2016) Wilson Mathias et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Ischaemic conditioning and reperfusion injury

(2016) Derek J. Hausenloy et al.   Nature Reviews Cardiology

Efficacy and Safety of Out-of-Hospital Intravenous Metoprolol Administration in Anterior ST-Segment Elevation Acute Myocardial Infarction: Insights From the METOCARD-CNIC Trial

(2015) Alonso Mateos et al.   ANNALS OF EMERGENCY MEDICINE

Cardioprotective Properties of the Platelet P2Y12 Receptor Inhibitor, Cangrelor: Protective in Diabetics and Reliant Upon the Presence of Blood

(2015) R. M. Bell et al.   CARDIOVASCULAR DRUGS AND THERAPY

Reflections on the Irreproducibility of Scientific Papers: Table.

(2015) Roberto Bolli   CIRCULATION RESEARCH

Cardiac Arrest: Resuscitation and Reperfusion

(2015) K. D. Patil et al.   CIRCULATION RESEARCH

Molecular Basis of Cardioprotection: Signal Transduction in Ischemic Pre-, Post-, and Remote Conditioning

(2015) G. Heusch   CIRCULATION RESEARCH

Long-Term Use of Cardiovascular Drugs

(2015) Xavier Rossello et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Remote Ischemic Conditioning

(2015) Gerd Heusch et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Myocardial Edema After Ischemia/Reperfusion Is Not Stable and Follows a Bimodal Pattern

(2015) Rodrigo Fernández-Jiménez et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Pathophysiology Underlying the Bimodal Edema Phenomenon After Myocardial Ischemia/Reperfusion

(2015) Rodrigo Fernández-Jiménez et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Evolving Therapies for Myocardial Ischemia/Reperfusion Injury

(2015) Borja Ibáñez et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Relation between door-to-balloon times and mortality after primary percutaneous coronary intervention over time: a retrospective study

(2015) Brahmajee K Nallamothu et al.   LANCET

Remote Ischemic Preconditioning and Outcomes of Cardiac Surgery

(2015) Derek J. Hausenloy et al.   NEW ENGLAND JOURNAL OF MEDICINE

A Multicenter Trial of Remote Ischemic Preconditioning for Heart Surgery

(2015) Patrick Meybohm et al.   NEW ENGLAND JOURNAL OF MEDICINE

Cyclosporine before PCI in Patients with Acute Myocardial Infarction

(2015) Thien-Tri Cung et al.   NEW ENGLAND JOURNAL OF MEDICINE

Determinants of the Efficacy of Cardiac Ischemic Preconditioning: A Systematic Review and Meta-Analysis of Animal Studies

(2015) Kimberley E. Wever et al.   PLoS One

Signalling pathways and mechanisms of protection in pre- and postconditioning: historical perspective and lessons for the future

(2014) Michael V Cohen et al.   BRITISH JOURNAL OF PHARMACOLOGY

ESC Working Group Cellular Biology of the Heart: Position Paper: improving the preclinical assessment of novel cardioprotective therapies

(2014) S. Lecour et al.   CARDIOVASCULAR RESEARCH

Reperfusion therapy for ST elevation acute myocardial infarction 2010/2011: current status in 37 ESC countries

(2014) S. D. Kristensen et al.   EUROPEAN HEART JOURNAL

The history of coronary reperfusion

(2014) Frans Van de Werf   EUROPEAN HEART JOURNAL

Association between clinical presentations before myocardial infarction and coronary mortality: a prospective population-based study using linked electronic records

(2014) Emily Herrett et al.   EUROPEAN HEART JOURNAL

Intracoronary injection of adenosine before reperfusion in patients with ST-segment elevation myocardial infarction: A randomized controlled clinical trial

(2014) David Garcia-Dorado et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Short- and Long-Term Cause of Death in Patients Treated With Primary PCI for STEMI

(2014) Frants Pedersen et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Long-Term Benefit of Early Pre-Reperfusion Metoprolol Administration in Patients With Acute Myocardial Infarction

(2014) Gonzalo Pizarro et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Top 10 cardiovascular therapies and interventions for the next decade

(2014) Valentin Fuster   Nature Reviews Cardiology

Improved Sonothrombolysis from a Modified Diagnostic Transducer Delivering Impulses Containing a Longer Pulse Duration

(2014) Juefei Wu et al.   ULTRASOUND IN MEDICINE AND BIOLOGY

Dipeptidyl peptidase-4 inhibitors and GLP-1 reduce myocardial infarct size in a glucose-dependent manner

(2013) Derek J Hausenloy et al.   Cardiovascular Diabetology

Glucose-Insulin-Potassium Revived

(2013) Alexandra N. Grossman et al.   CIRCULATION

Effect of Early Metoprolol on Infarct Size in ST-Segment–Elevation Myocardial Infarction Patients Undergoing Primary Percutaneous Coronary Intervention

(2013) Borja Ibanez et al.   CIRCULATION

The bumpy road to evidence: why many research findings are lost in translation

(2013) T. F. Luscher   EUROPEAN HEART JOURNAL

Open-Label, Randomized, Placebo-Controlled Evaluation of Intracoronary Adenosine or Nitroprusside After Thrombus Aspiration During Primary Percutaneous Coronary Intervention for the Prevention of Microvascular Obstruction in Acute Myocardial Infarction

(2013) Giampaolo Niccoli et al.   JACC-Cardiovascular Interventions

Door-to-Balloon Time and Mortality among Patients Undergoing Primary PCI

(2013) Daniel S. Menees et al.   NEW ENGLAND JOURNAL OF MEDICINE

Genetic background, gender, age, body temperature, and arterial blood pH have a major impact on myocardial infarct size in the mouse and need to be carefully measured and/or taken into account: results of a comprehensive analysis of determinants of infarct size in 1,074 mice

(2012) Yiru Guo et al.   BASIC RESEARCH IN CARDIOLOGY

Exenatide Reduces Final Infarct Size in Patients With ST-Segment–Elevation Myocardial Infarction and Short-Duration of Ischemia

(2012) Jacob Lønborg et al.   Circulation-Cardiovascular Interventions

Out-of-Hospital Administration of Intravenous Glucose-Insulin-Potassium in Patients With Suspected Acute Coronary Syndromes

(2012) Joni R. Beshansky   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Platelet P2Y12 Blockers Confer Direct Postconditioning-Like Protection in Reperfused Rabbit Hearts

(2012) Xi-Ming Yang et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY AND THERAPEUTICS

Conditioning the whole heart—not just the cardiomyocyte

(2012) Robert M. Bell et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Cardioprotection: chances and challenges of its translation to the clinic

(2012) Gerd Heusch   LANCET

Acute erythropoietin cardioprotection is mediated by endothelial response

(2011) Ruifeng Teng et al.   BASIC RESEARCH IN CARDIOLOGY

Cyclosporin variably and inconsistently reduces infarct size in experimental models of reperfused myocardial infarction: a systematic review and meta-analysis

(2011) WY Lim et al.   BRITISH JOURNAL OF PHARMACOLOGY

High-dose intracoronary adenosine for myocardial salvage in patients with acute ST-segment elevation myocardial infarction

(2011) W. Desmet et al.   EUROPEAN HEART JOURNAL

Ischaemic postconditioning revisited: lack of effects on infarct size following primary percutaneous coronary intervention

(2011) X. Freixa et al.   EUROPEAN HEART JOURNAL

Exenatide reduces reperfusion injury in patients with ST-segment elevation myocardial infarction

(2011) Jacob Lønborg et al.   EUROPEAN HEART JOURNAL

Impact of High-Dose N-Acetylcysteine Versus Placebo on Contrast-Induced Nephropathy and Myocardial Reperfusion Injury in Unselected Patients With ST-Segment Elevation Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention

(2010) Holger Thiele et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Remote ischaemic conditioning before hospital admission, as a complement to angioplasty, and effect on myocardial salvage in patients with acute myocardial infarction: a randomised trial

(2010) Hans Erik Bøtker et al.   LANCET

Effect of High-Dose Intracoronary Adenosine Administration During Primary Percutaneous Coronary Intervention in Acute Myocardial Infarction

(2009) Marieke L. Fokkema et al.   Circulation-Cardiovascular Interventions

The cardioprotection granted by metoprolol is restricted to its administration prior to coronary reperfusion

(2009) Borja Ibanez et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Multiple protective pathways against reperfusion injury: A SAFE path without Aktion?

(2009) Sandrine Lecour   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Improvements in Long-Term Mortality After Myocardial Infarction and Increased Use of Cardiovascular Drugs After Discharge

(2008) Soko Setoguchi et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY