Novel insights into the role of mitochondrial fusion and fission in cardiomyocyte apoptosis induced by ischemia/reperfusion

Mitochondrial PKC-ε deficiency promotes I/R-mediated myocardial injury via GSK3β-dependent mitochondrial permeability transition pore opening

(2017) Shijun Wang et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

SENP3-mediated deSUMOylation of Drp1 facilitates interaction with Mff to promote cell death

(2017) Chun Guo et al.   Scientific Reports

PDE2A2 regulates mitochondria morphology and apoptotic cell death via local modulation of cAMP/PKA signalling

(2017) Stefania Monterisi et al.   eLife

High glucose concentration abrogates sevoflurane post-conditioning cardioprotection by advancing mitochondrial fission but dynamin-related protein 1 inhibitor restores these effects

(2016) J. Yu et al.   Acta Physiologica

Inhibition of mitochondrial fission as a molecular target for cardioprotection: critical importance of the timing of treatment

(2016) Yi Dong et al.   BASIC RESEARCH IN CARDIOLOGY

The role of Drp1 adaptor proteins MiD49 and MiD51 in mitochondrial fission: implications for human disease

(2016) K. Atkins et al.   CLINICAL SCIENCE

Linking mitochondrial dynamics to mitochondrial protein quality control

(2016) Suraiya Haroon et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Cooperative and independent roles of the Drp1 adaptors Mff, MiD49 and MiD51 in mitochondrial fission

(2016) Laura D. Osellame et al.   JOURNAL OF CELL SCIENCE

Rg1 prevents myocardial hypoxia/reoxygenation injury by regulating mitochondrial dynamics imbalance via modulation of glutamate dehydrogenase and mitofusin 2

(2016) Gengting Dong et al.   MITOCHONDRION

Remote Ischemic Conditioning Influences Mitochondrial Dynamics

(2016) Laura Cellier et al.   SHOCK

Hearts deficient in both Mfn1 and Mfn2 are protected against acute myocardial infarction

(2016) A R Hall et al.   Cell Death & Disease

Nanoparticle‐Mediated Delivery of Mitochondrial Division Inhibitor 1 to the Myocardium Protects the Heart From Ischemia‐Reperfusion Injury Through Inhibition of Mitochondria Outer Membrane Permeabilization: A New Therapeutic Modality for Acute Myocardial Infarction

(2016) Ayako Ishikita et al.   Journal of the American Heart Association

Sevoflurane postconditioning attenuates cardiomyocyte hypoxia/reoxygenation injury via restoring mitochondrial morphology

(2016) Jin Yu et al.   PeerJ

Increase in Cardiac Ischemia-Reperfusion Injuries in Opa1+/- Mouse Model

(2016) Sophie Le Page et al.   PLoS One

The Opa1-Dependent Mitochondrial Cristae Remodeling Pathway Controls Atrophic, Apoptotic, and Ischemic Tissue Damage

(2015) Tatiana Varanita et al.   Cell Metabolism

Interdependence of Parkin-Mediated Mitophagy and Mitochondrial Fission in Adult Mouse HeartsNovelty and Significance

(2015) Moshi Song et al.   CIRCULATION RESEARCH

Mitochondrial Reactive Oxygen Species at the Heart of the Matter: New Therapeutic Approaches for Cardiovascular Diseases

(2015) O. S. Kornfeld et al.   CIRCULATION RESEARCH

OPA1 in Cardiovascular Health and Disease

(2015) Niall Burke et al.   CURRENT DRUG TARGETS

Role of mitochondrial fission and fusion in cardiomyocyte contractility

(2015) S. Givvimani et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

SENP5, a SUMO isopeptidase, induces apoptosis and cardiomyopathy

(2015) Eun Young Kim et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Pharmacological activation of AMPK prevents Drp1-mediated mitochondrial fission and alleviates endoplasmic reticulum stress-associated endothelial dysfunction

(2015) Jia Li et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

The mitochondrial fission receptor Mff selectively recruits oligomerized Drp1

(2015) Raymond Liu et al.   MOLECULAR BIOLOGY OF THE CELL

Imbalanced OPA1 processing and mitochondrial fragmentation cause heart failure in mice

(2015) T. Wai et al.   SCIENCE

NFAT4-dependent miR-324-5p regulates mitochondrial morphology and cardiomyocyte cell death by targeting Mtfr1

(2015) K Wang et al.   Cell Death & Disease

Cdk1, PKCδ and calcineurin-mediated Drp1 pathway contributes to mitochondrial fission-induced cardiomyocyte death

(2014) Ivan Zaja et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Drp1 Loss-of-function Reduces Cardiomyocyte Oxygen Dependence Protecting the Heart From Ischemia-reperfusion Injury

(2014) Ramiro Zepeda et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

Mitofusin 1 Is Negatively Regulated by MicroRNA 140 in Cardiomyocyte Apoptosis

(2014) J. Li et al.   MOLECULAR AND CELLULAR BIOLOGY

New Insights into the Role of Mitochondrial Dynamics and Autophagy during Oxidative Stress and Aging in the Heart

(2014) Yoshiyuki Ikeda et al.   Oxidative Medicine and Cellular Longevity

DJ-1 protects against cell death following acute cardiac ischemia–reperfusion injury

(2014) R K Dongworth et al.   Cell Death & Disease

Nitrite activates protein kinase A in normoxia to mediate mitochondrial fusion and tolerance to ischaemia/reperfusion

(2013) Christelle Kamga Pride et al.   CARDIOVASCULAR RESEARCH

SENP3-mediated deSUMOylation of dynamin-related protein 1 promotes cell death following ischaemia

(2013) Chun Guo et al.   EMBO JOURNAL

Dynamin-related protein 1 (Drp1)-mediated diastolic dysfunction in myocardial ischemia-reperfusion injury: therapeutic benefits of Drp1 inhibition to reduce mitochondrial fission

(2013) Willard W. Sharp et al.   FASEB JOURNAL

miR-761 regulates the mitochondrial network by targeting mitochondrial fission factor

(2013) Bo Long et al.   FREE RADICAL BIOLOGY AND MEDICINE

Dynasore Protects Mitochondria and Improves Cardiac Lusitropy in Langendorff Perfused Mouse Heart

(2013) Danchen Gao et al.   PLoS One

Pim-1 preserves mitochondrial morphology by inhibiting dynamin-related protein 1 translocation

(2013) S. Din et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

OPA1 Mutation and Late‐Onset Cardiomyopathy: Mitochondrial Dysfunction and mtDNA Instability

(2013) Le Chen et al.   Journal of the American Heart Association

Acute Inhibition of Excessive Mitochondrial Fission After Myocardial Infarction Prevents Long‐term Cardiac Dysfunction

(2013) Marie‐Hélène Disatnik et al.   Journal of the American Heart Association

Mitochondrial dynamics in the adult cardiomyocytes: which roles for a highly specialized cell?

(2013) Jerome Piquereau et al.   Frontiers in Physiology

Down-regulation of OPA1 alters mouse mitochondrial morphology, PTP function, and cardiac adaptation to pressure overload

(2012) Jerome Piquereau et al.   CARDIOVASCULAR RESEARCH

Central Role of Mitofusin 2 in Autophagosome-Lysosome Fusion in Cardiomyocytes

(2012) Ting Zhao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

GSK3beta-Mediated Drp1 Phosphorylation Induced Elongated Mitochondrial Morphology against Oxidative Stress

(2012) Chia-Hua Chou et al.   PLoS One

Cardiomyocyte deletion of mitofusin-1 leads to mitochondrial fragmentation and improves tolerance to ROS-induced mitochondrial dysfunction and cell death

(2011) Kyriakos N. Papanicolaou et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

New roles for mitochondria in cell death in the reperfused myocardium

(2011) S.-B. Ong et al.   CARDIOVASCULAR RESEARCH

Mitochondrial Fusion is Essential for Organelle Function and Cardiac Homeostasis

(2011) Yun Chen et al.   CIRCULATION RESEARCH

Mitofusin-2 Maintains Mitochondrial Structure and Contributes to Stress-Induced Permeability Transition in Cardiac Myocytes

(2011) K. N. Papanicolaou et al.   MOLECULAR AND CELLULAR BIOLOGY

Mitochondrial morphology and cardiovascular disease

(2010) S.-B. Ong et al.   CARDIOVASCULAR RESEARCH

Inhibiting Mitochondrial Fission Protects the Heart Against Ischemia/Reperfusion Injury

(2010) Sang-Bing Ong et al.   CIRCULATION

Sumoylation and Regulation of Cardiac Gene Expression

(2010) Jun Wang et al.   CIRCULATION RESEARCH

MARF and Opa1 Control Mitochondrial and Cardiac Function in Drosophila

(2010) Gerald W. Dorn et al.   CIRCULATION RESEARCH

Mff is an essential factor for mitochondrial recruitment of Drp1 during mitochondrial fission in mammalian cells

(2010) Hidenori Otera et al.   JOURNAL OF CELL BIOLOGY

The nuclear genes Mtfr1 and Dufd1 regulate mitochondrial dynamic and cellular respiration

(2010) Massimiliano Monticone et al.   JOURNAL OF CELLULAR PHYSIOLOGY

miR-499 regulates mitochondrial dynamics by targeting calcineurin and dynamin-related protein-1

(2010) Jian-Xun Wang et al.   NATURE MEDICINE

miR-30 Regulates Mitochondrial Fission through Targeting p53 and the Dynamin-Related Protein-1 Pathway

(2010) Jincheng Li et al.   PLoS Genetics

A Mutation in the Mitochondrial Fission Gene Dnm1l Leads to Cardiomyopathy

(2010) Houman Ashrafian et al.   PLoS Genetics

SUMOylation of the mitochondrial fission protein Drp1 occurs at multiple nonconsensus sites within the B domain and is linked to its activity cycle

(2009) Claudia Figueroa-Romero et al.   FASEB JOURNAL

Morphological dynamics of mitochondria — A special emphasis on cardiac muscle cells

(2009) Jennifer Hom et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Mitochondrial fusion, fission and autophagy as a quality control axis: The bioenergetic view

(2008) Gilad Twig et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Mitochondrial biogenesis and turnover

(2008) F DIAZ et al.   CELL CALCIUM

CaM kinase Iα–induced phosphorylation of Drp1 regulates mitochondrial morphology

(2008) Xiao-Jian Han et al.   JOURNAL OF CELL BIOLOGY

Dephosphorylation by calcineurin regulates translocation of Drp1 to mitochondria

(2008) G. M. Cereghetti et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA