A Sesquiterpenoid from Farfarae Flos Induces Apoptosis of MDA-MB-231 Human Breast Cancer Cells through Inhibition of JAK–STAT3 Signaling

Bazedoxifene exhibits growth suppressive activity by Targeting IL-6/GP130/STAT3 Signaling in Hepatocellular Carcinoma

(2019) Haiyan Ma et al.   CANCER SCIENCE

BP‑1‑102 exerts an antitumor effect on the AGS human gastric cancer cell line through modulating the STAT3 and MAPK signaling pathways

(2019) Xiaoxia Jiang et al.   Molecular Medicine Reports

Novel Galiellalactone Analogues Can Target STAT3 Phosphorylation and Cause Apoptosis in Triple-Negative Breast Cancer

(2019) Hyejin Ko et al.   Biomolecules

Neuroprotection against 6-OHDA toxicity in PC12 cells and mice through the Nrf2 pathway by a sesquiterpenoid from Tussilago farfara

(2018) Joohee Lee et al.   Redox Biology

Bioassay-guided isolation of cantharidin from blister beetles and its anticancer activity through inhibition of epidermal growth factor receptor-mediated STAT3 and Akt pathways

(2018) Jaemoo Chun et al.   Journal of Natural Medicines

Tussilagonone-induced Nrf2 pathway activation protects HepG2 cells from oxidative injury

(2017) Kyung-Mi Lee et al.   FOOD AND CHEMICAL TOXICOLOGY

Development of an efficient fractionation method for the preparative separation of sesquiterpenoids from Tussilago farfara by counter-current chromatography

(2017) Kwangho Song et al.   JOURNAL OF CHROMATOGRAPHY A

Genomic regulation of invasion by STAT3 in triple negative breast cancer

(2016) Joy M. McDaniel et al.   Oncotarget

Sesquiterpenoids from Tussilago farfara inhibit LPS-induced nitric oxide production in macrophage RAW 264.7 cells

(2015) Hari Jang et al.   ARCHIVES OF PHARMACAL RESEARCH

Global cancer statistics, 2012

(2015) Lindsey A. Torre et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Alantolactone selectively suppresses STAT3 activation and exhibits potent anticancer activity in MDA-MB-231 cells

(2015) Jaemoo Chun et al.   CANCER LETTERS

Antitubercular activity of Arctium lappa and Tussilago farfara extracts and constituents

(2014) Jinlian Zhao et al.   JOURNAL OF ETHNOPHARMACOLOGY

Thymoquinone induces apoptosis in human colon cancer HCT116 cells through inactivation of STAT3 by blocking JAK2- and Src-mediated phosphorylation of EGF receptor tyrosine kinase

(2014) JUTHIKA KUNDU et al.   ONCOLOGY REPORTS

STAT3 Target Genes Relevant to Human Cancers

(2014) Richard Carpenter et al.   Cancers

Platycodin D inhibits migration, invasion, and growth of MDA-MB-231 human breast cancer cells via suppression of EGFR-mediated Akt and MAPK pathways

(2013) Jaemoo Chun et al.   CHEMICO-BIOLOGICAL INTERACTIONS

STAT3 activation in response to IL-6 is prolonged by the binding of IL-6 receptor to EGF receptor

(2013) Y. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Triple-negative breast cancer: epidemiological considerations and recommendations

(2012) P. Boyle   ANNALS OF ONCOLOGY

Expression and Clinical Significance of STAT3, P-STAT3, and VEGF-C in Small Cell Lung Cancer

(2012) Xue Zhao et al.   Asian Pacific Journal of Cancer Prevention

Targeting the Interleukin-6/Jak/Stat Pathway in Human Malignancies

(2012) Pasquale Sansone et al.   JOURNAL OF CLINICAL ONCOLOGY

6-Bromoindirubin-3'-Oxime Inhibits JAK/STAT3 Signaling and Induces Apoptosis of Human Melanoma Cells

(2011) L. Liu et al.   CANCER RESEARCH

Small Molecule Inhibitors of STAT3 for Cancer Therapy

(2011) M. Zhao et al.   CURRENT MEDICINAL CHEMISTRY

New sesquiterpenoids from the dried flower buds of Tussilago farfara and their inhibition on NO production in LPS-induced RAW264.7 cells

(2011) Wei Li et al.   FITOTERAPIA

Triple-Negative Breast Cancer

(2010) William D. Foulkes et al.   NEW ENGLAND JOURNAL OF MEDICINE

STAT3 Is Required for Proliferation and Maintenance of Multipotency in Glioblastoma Stem Cells

(2009) Maureen M. Sherry et al.   STEM CELLS

Triple-negative high-risk breast cancer derives particular benefit from dose intensification of adjuvant chemotherapy: results of WSG AM-01 trial

(2008) O. Gluz et al.   ANNALS OF ONCOLOGY

What is triple-negative breast cancer?

(2008) William J. Irvin et al.   EUROPEAN JOURNAL OF CANCER

Sesquiterpenoids Isolated from the Flower Buds of Tussilago farfara L. Inhibit Diacylglycerol Acyltransferase

(2008) Hye Ran Park et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY