Bioassay-guided isolation of cantharidin from blister beetles and its anticancer activity through inhibition of epidermal growth factor receptor-mediated STAT3 and Akt pathways

Stress-induced EGF receptor signaling through STAT3 and tumor progression in triple-negative breast cancer

(2017) Nikolas Balanis et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Targeting transcription factor STAT3 for cancer prevention and therapy

(2016) Edna Zhi Pei Chai et al.   PHARMACOLOGY & THERAPEUTICS

Suspension survival mediated by PP2A-STAT3-Col XVII determines tumour initiation and metastasis in cancer stem cells

(2016) Chen-Chi Liu et al.   Nature Communications

Genomic regulation of invasion by STAT3 in triple negative breast cancer

(2016) Joy M. McDaniel et al.   Oncotarget

Cantharidin Induces Apoptosis Through the Calcium/PKC-Regulated Endoplasmic Reticulum Stress Pathway in Human Bladder Cancer Cells

(2015) Chin-Chuan Su et al.   AMERICAN JOURNAL OF CHINESE MEDICINE

Alantolactone selectively suppresses STAT3 activation and exhibits potent anticancer activity in MDA-MB-231 cells

(2015) Jaemoo Chun et al.   CANCER LETTERS

Phosphatidic Acid (PA) can Displace PPARα/LXRα Binding to The EGFR Promoter Causing its Transrepression in Luminal Cancer Cells

(2015) Madhu Mahankali et al.   Scientific Reports

Cantharidin inhibits angiogenesis by suppressing VEGF-induced JAK1/STAT3, ERK and AKT signaling pathways

(2014) Ting Wang et al.   ARCHIVES OF PHARMACAL RESEARCH

Reduced phosphorylation of Stat3 at Ser-727 mediated by casein kinase 2 — Protein phosphatase 2A enhances Stat3 Tyr-705 induced tumorigenic potential of glioma cells

(2014) Tapashi Mandal et al.   CELLULAR SIGNALLING

Triple-negative breast cancer: epidemiological considerations and recommendations

(2012) P. Boyle   ANNALS OF ONCOLOGY

Fighting fire with fire: Poisonous Chinese herbal medicine for cancer therapy

(2012) Shengpeng Wang et al.   JOURNAL OF ETHNOPHARMACOLOGY

Triple negative breast cancer: unmet medical needs

(2010) Sumanta Kumar Pal et al.   BREAST CANCER RESEARCH AND TREATMENT

Cantharidin, a potent and selective PP2A inhibitor, induces an oxidative stress-independent growth inhibition of pancreatic cancer cells through G2/M cell-cycle arrest and apoptosis

(2010) Wei Li et al.   CANCER SCIENCE

Triple-Negative Breast Cancer

(2010) William D. Foulkes et al.   NEW ENGLAND JOURNAL OF MEDICINE