Single-Cell Receptor Quantification of an In Vitro Coculture Angiogenesis Model Reveals VEGFR, NRP1, Tie2, and PDGFR Regulation and Endothelial Heterogeneity

Consensus guidelines for the use and interpretation of angiogenesis assays

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Dynamic, heterogeneous endothelial Tie2 expression and capillary blood flow during microvascular remodeling

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Targeting the Angiopoietin-2/Tie-2 axis in conjunction with VEGF signal interference

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Mechanism of FGF receptor dimerization and activation

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Vascular endothelial growth factor D expression is a potential biomarker of bevacizumab benefit in colorectal cancer

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Quantification of VEGFRs, NRP1, and PDGFRs on Endothelial Cells and Fibroblasts Reveals Serum, Intra-Family Ligand, and Cross-Family Ligand Regulation

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Computational systems biology approaches to anti-angiogenic cancer therapeutics

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Single-cell analysis tools for drug discovery and development

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HCMV glycoprotein B is expressed in primary glioblastomas and enhances growth and invasiveness via PDGFR-alpha activation

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Quantitative Characterization of Cellular Membrane-Receptor Heterogeneity through Statistical and Computational Modeling

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Quantitative fluorescent profiling of VEGFRs reveals tumor cell and endothelial cell heterogeneity in breast cancer xenografts

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Endothelial cell-by-cell profiling reveals the temporal dynamics of VEGFR1 and VEGFR2 membrane localization after murine hindlimb ischemia

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Single-cell imaging mass spectrometry

(2013) Melissa K Passarelli et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Quantitative single-cell RNA-seq with unique molecular identifiers

(2013) Saiful Islam et al.   NATURE METHODS

In Vitro Perfused Human Capillary Networks

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Signal Transduction by Vascular Endothelial Growth Factor Receptors

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Fluid shear stress induces differentiation of circulating phenotype endothelial progenitor cells

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Role of shear-stress-induced VEGF expression in endothelial cell survival

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Endothelial Tip Cells in Ocular Angiogenesis

(2012) Martin J. Siemerink et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

Expression of VEGF Receptors on Endothelial Cells in Mouse Skeletal Muscle

(2012) Princess I. Imoukhuede et al.   PLoS One

Intussusceptive angiogenesis: pillars against the blood flow

(2011) B. Styp-Rekowska et al.   Acta Physiologica

Data-driven modelling of receptor tyrosine kinase signalling networks quantifies receptor-specific potencies of PI3K- and Ras-dependent ERK activation

(2011) Murat Cirit et al.   BIOCHEMICAL JOURNAL

Formation of VEGF isoform-specific spatial distributions governing angiogenesis: computational analysis

(2011) Prakash Vempati et al.   BMC Systems Biology

Pharmacokinetics and pharmacodynamics of VEGF-neutralizing antibodies

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Impact of receptor clustering on ligand binding

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Pericytes: Developmental, Physiological, and Pathological Perspectives, Problems, and Promises

(2011) Annika Armulik et al.   DEVELOPMENTAL CELL

Targeting FGFR/PDGFR/VEGFR Impairs Tumor Growth, Angiogenesis, and Metastasis by Effects on Tumor Cells, Endothelial Cells, and Pericytes in Pancreatic Cancer

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A Computational Tool for Quantitative Analysis of Vascular Networks

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Single-cell proteomic chip for profiling intracellular signaling pathways in single tumor cells

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Module-based multiscale simulation of angiogenesis in skeletal muscle

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Increase of Plasma VEGF after Intravenous Administration of Bevacizumab Is Predicted by a Pharmacokinetic Model

(2010) M. O. Stefanini et al.   CANCER RESEARCH

Quantification and cell-to-cell variation of vascular endothelial growth factor receptors

(2010) P.I. Imoukhuede et al.   EXPERIMENTAL CELL RESEARCH

A critical analysis of current in vitro and in vivo angiogenesis assays

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Quantifying the Proteolytic Release of Extracellular Matrix-Sequestered VEGF with a Computational Model

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Systems biology of pro-angiogenic therapies targeting the VEGF system

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Endothelial-Mural Cell Signaling in Vascular Development and Angiogenesis

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Pericyte recruitment during vasculogenic tube assembly stimulates endothelial basement membrane matrix formation

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Elongation, proliferation & migration differentiate endothelial cell phenotypes and determine capillary sprouting

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Multiscale models of angiogenesis

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The aortic ring model of angiogenesis: a quarter century of search and discovery

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Mural Cell Associated VEGF Is Required for Organotypic Vessel Formation

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Pericytes and Perivascular Fibroblasts Are the Primary Source of Collagen-Producing Cells in Obstructive Fibrosis of the Kidney

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Molecular heterogeneity of tumor endothelium

(2008) William C. Aird   CELL AND TISSUE RESEARCH

Differential roles of PDGFR-α and PDGFR-β in angiogenesis and vessel stability

(2008) Junhang Zhang et al.   FASEB JOURNAL

Role of platelet-derived growth factors in physiology and medicine

(2008) J. Andrae et al.   GENES & DEVELOPMENT

Strikingly Different Angiogenic Properties of Endothelial Progenitor Cell Subpopulations

(2008) Daniel P. Sieveking et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Systems Biology of Vascular Endothelial Growth Factors

(2008) Feilim Mac Gabhann et al.   MICROCIRCULATION

Differential function of Tie2 at cell–cell contacts and cell–substratum contacts regulated by angiopoietin-1

(2008) Shigetomo Fukuhara et al.   NATURE CELL BIOLOGY

Angiopoietins assemble distinct Tie2 signalling complexes in endothelial cell–cell and cell–matrix contacts

(2008) Pipsa Saharinen et al.   NATURE CELL BIOLOGY