Cisplatin Eligibility Issues and Alternative Regimens in Locoregionally Advanced Head and Neck Cancer: Recommendations for Clinical Practice

Low-Dose vs. High-Dose Cisplatin: Lessons Learned From 59 Chemoradiotherapy Trials in Head and Neck Cancer

(2019) Petr Szturz et al.   Frontiers in Oncology

Systemic treatment in elderly head and neck cancer patients

(2019) Petr Szturz et al.   Current Opinion in Otolaryngology & Head and Neck Surgery

Postoperative Concurrent Chemoradiotherapy Versus Postoperative Radiotherapy in High-Risk Cutaneous Squamous Cell Carcinoma of the Head and Neck: The Randomized Phase III TROG 05.01 Trial

(2018) Sandro Virgilio Porceddu et al.   JOURNAL OF CLINICAL ONCOLOGY

Improved Outcome by Adding Concurrent Chemotherapy to Cetuximab and Radiotherapy for Locally Advanced Head and Neck Carcinomas: Results of the GORTEC 2007-01 Phase III Randomized Trial

(2018) Yungan Tao et al.   JOURNAL OF CLINICAL ONCOLOGY

Once-a-Week Versus Once-Every-3-Weeks Cisplatin Chemoradiation for Locally Advanced Head and Neck Cancer: A Phase III Randomized Noninferiority Trial

(2018) Vanita Noronha et al.   JOURNAL OF CLINICAL ONCOLOGY

Altered fractionation radiotherapy combined with concurrent low-dose or high-dose cisplatin in head and neck cancer: A systematic review of literature and meta-analysis

(2018) Petr Szturz et al.   ORAL ONCOLOGY

Global migration of clinical research during the era of trial registration

(2018) Paul K. Drain et al.   PLoS One

Cisplatin (CIS) versus cetuximab (CET) with definitive concurrent radiotherapy (RT) for head and neck squamous cell carcinoma (HNSCC): An analysis of veteran’s health data.

(2018) Joshua Bauml et al.   JOURNAL OF CLINICAL ONCOLOGY

Radiotherapy plus cisplatin or cetuximab in low-risk human papillomavirus-positive oropharyngeal cancer (De-ESCALaTE HPV): an open-label randomised controlled phase 3 trial

(2018) Hisham Mehanna et al.   LANCET

Radiotherapy plus cetuximab or cisplatin in human papillomavirus-positive oropharyngeal cancer (NRG Oncology RTOG 1016): a randomised, multicentre, non-inferiority trial

(2018) Maura L Gillison et al.   LANCET

Reduced-dose radiotherapy for human papillomavirus-associated squamous-cell carcinoma of the oropharynx: a single-arm, phase 2 study

(2017) Allen M Chen et al.   LANCET ONCOLOGY

Role of radiotherapy fractionation in head and neck cancers (MARCH): an updated meta-analysis

(2017) Benjamin Lacas et al.   LANCET ONCOLOGY

Weekly Low‐Dose Versus Three‐Weekly High‐Dose Cisplatin for Concurrent Chemoradiation in Locoregionally Advanced Non‐Nasopharyngeal Head and Neck Cancer: A Systematic Review and Meta‐Analysis of Aggregate Data

(2017) Petr Szturz et al.   ONCOLOGIST

A phase III trial (RTOG 0129) of two radiation-cisplatin regimens for head and neck carcinomas (HNC): Impact of radiation and cisplatin intensity on outcome.

(2017) K. Ang et al.   JOURNAL OF CLINICAL ONCOLOGY

Use of systemic therapy with definitive radiotherapy for elderly patients with head and neck cancer: A National Cancer Data Base analysis

(2016) Matthew C. Ward et al.   CANCER

Impact of cisplatin dose intensity on human papillomavirus-related and -unrelated locally advanced head and neck squamous cell carcinoma

(2016) Anna Spreafico et al.   EUROPEAN JOURNAL OF CANCER

Concurrent cetuximab and postoperative radiation in resected high-risk squamous cell carcinomas of the head and neck: A single-institution experience

(2016) Daisuke Araki et al.   HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK

Cetuximab and Radiotherapy Versus Cisplatin and Radiotherapy for Locally Advanced Head and Neck Cancer: A Randomized Phase II Trial

(2016) Stefano Maria Magrini et al.   JOURNAL OF CLINICAL ONCOLOGY

Development and validation of a staging system for HPV-related oropharyngeal cancer by the International Collaboration on Oropharyngeal cancer Network for Staging (ICON-S): a multicentre cohort study

(2016) Brian O'Sullivan et al.   LANCET ONCOLOGY

Clinical recommendations for defining platinum unsuitable head and neck cancer patient populations on chemoradiotherapy: A literature review

(2016) Myung-Ju Ahn et al.   ORAL ONCOLOGY

Conventional radiotherapy versus concurrent chemoradiotherapy versus accelerated radiotherapy in locoregionally advanced carcinoma of head and neck: Results of a prospective randomized trial

(2015) Sarbani Ghosh-Laskar et al.   HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK

Cumulative cisplatin dose in concurrent chemoradiotherapy for head and neck cancer: A systematic review

(2015) Primož Strojan et al.   HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK

Expanding global access to radiotherapy

(2015) Rifat Atun et al.   LANCET ONCOLOGY

Randomized Phase III Trial to Test Accelerated Versus Standard Fractionation in Combination With Concurrent Cisplatin for Head and Neck Carcinomas in the Radiation Therapy Oncology Group 0129 Trial: Long-Term Report of Efficacy and Toxicity

(2014) Phuc Felix Nguyen-Tan et al.   JOURNAL OF CLINICAL ONCOLOGY

Postoperative Chemoradiotherapy and Cetuximab for High-Risk Squamous Cell Carcinoma of the Head and Neck: Radiation Therapy Oncology Group RTOG-0234

(2014) Paul M. Harari et al.   JOURNAL OF CLINICAL ONCOLOGY

Epidemiology of HPV-associated oropharyngeal cancer

(2014) Kristen B. Pytynia et al.   ORAL ONCOLOGY

Concomitant platinum-based chemotherapy or cetuximab with radiotherapy for locally advanced head and neck cancer: A systematic review and meta-analysis of published studies

(2014) Fausto Petrelli et al.   ORAL ONCOLOGY

Long-term Follow-up of the RTOG 9501/Intergroup Phase III Trial: Postoperative Concurrent Radiation Therapy and Chemotherapy in High-Risk Squamous Cell Carcinoma of the Head and Neck

(2012) Jay S. Cooper et al.   INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

Long-Term Results of RTOG 91-11: A Comparison of Three Nonsurgical Treatment Strategies to Preserve the Larynx in Patients With Locally Advanced Larynx Cancer

(2012) Arlene A. Forastiere et al.   JOURNAL OF CLINICAL ONCOLOGY

Absent benefit of accelerated concomitant chemoradiotherapy – Authors' reply

(2012) Jean Bourhis et al.   LANCET ONCOLOGY

Concomitant chemoradiotherapy versus acceleration of radiotherapy with or without concomitant chemotherapy in locally advanced head and neck carcinoma (GORTEC 99-02): an open-label phase 3 randomised trial

(2012) Jean Bourhis et al.   LANCET ONCOLOGY

The comparison between weekly and three-weekly cisplatin delivered concurrently with radiotherapy for patients with postoperative high-risk squamous cell carcinoma of the oral cavity

(2012) Din-Li Tsan et al.   Radiation Oncology

Efficacy and tolerability of weekly low-dose cisplatin concurrent with radiotherapy in head and neck cancer patients

(2011) Zulfiquer OTTY et al.   Asia-Pacific Journal of Clinical Oncology

Concomitant chemoradiation versus radical radiotherapy in advanced squamous cell carcinoma of oropharynx and nasopharynx using weekly cisplatin: a phase II randomized trial

(2010) A. Sharma et al.   ANNALS OF ONCOLOGY

Squamous cell carcinoma of the head and neck: EHNS-ESMO-ESTRO Clinical Practice Guidelines for diagnosis, treatment and follow-up

(2010) V. Gregoire et al.   ANNALS OF ONCOLOGY

Cost-effectiveness analysis of cisplatin-based chemoradiation to treat patients with unresectable, nonmetastatic head and neck cancer in Brazil

(2010) Alexandra Brentani et al.   HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK

Phase III Study of Radiation Therapy With or Without Cis-Platinum in Patients With Unresectable Squamous or Undifferentiated Carcinoma of the Head and Neck: An Intergroup Trial of the Eastern Cooperative Oncology Group (E2382)

(2010) Harry Quon et al.   INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

Comorbidity in head and neck cancer: A critical appraisal and recommendations for practice

(2010) Vinidh Paleri et al.   ORAL ONCOLOGY

Long-Term Results of a Phase III Randomized Trial of Postoperative Radiotherapy With or Without Carboplatin in Patients With High-Risk Head and Neck Cancer

(2009) Athanassios Argiris et al.   LARYNGOSCOPE

Meta-analysis of chemotherapy in head and neck cancer (MACH-NC): An update on 93 randomised trials and 17,346 patients

(2009) Jean-Pierre Pignon et al.   RADIOTHERAPY AND ONCOLOGY

Head and neck cancer

(2008) Athanassios Argiris et al.   LANCET