The IL4I1 Enzyme: A New Player in the Immunosuppressive Tumor Microenvironment

Proteomic definition of human mucosal-associated invariant T cells determines their unique molecular effector phenotype

(2018) Björn Bulitta et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Emerging Role of IL-4–Induced Gene 1 as a Prognostic Biomarker Affecting the Local T-Cell Response in Human Cutaneous Melanoma

(2018) Jan Philipp Ramspott et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

IL-4–Induced Gene 1: A Negative Immune Checkpoint Controlling B Cell Differentiation and Activation

(2017) Lloyd Bod et al.   JOURNAL OF IMMUNOLOGY

Quantitative Analysis of Proteome Modulations in Alveolar Epithelial Type II Cells in Response to PulmonaryAspergillus fumigatusInfection

(2017) Pegah Seddigh et al.   MOLECULAR & CELLULAR PROTEOMICS

The Human Cell Atlas

(2017) Aviv Regev et al.   eLife

IL4-induced gene 1 promotes tumor growth by shaping the immune microenvironment in melanoma

(2017) Lloyd Bod et al.   OncoImmunology

IL4I1 augments CNS remyelination and axonal protection by modulating T cell driven inflammation

(2016) Konstantina Psachoulia et al.   BRAIN

IL4I1: Key immunoregulator at a crossroads of divergent T-cell functions

(2016) Sergio Romagnani   EUROPEAN JOURNAL OF IMMUNOLOGY

Candida albicans Modifies the Protein Composition and Size Distribution of THP-1 Macrophage-Derived Extracellular Vesicles

(2016) Jose Antonio Reales-Calderón et al.   JOURNAL OF PROTEOME RESEARCH

Differential expression of the immunosuppressive enzyme IL4I1 in human induced Aiolos+, but not natural Helios+, FOXP3+Treg cells

(2015) Clara-Maria Scarlata et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

The immunosuppressive enzyme IL4I1 promotes FoxP3+regulatory T lymphocyte differentiation

(2015) Céline Cousin et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Alterations of the immunosuppressive IL4I1 enzyme activity induced by naturally occurring SNP/mutations

(2015) V Molinier-Frenkel et al.   GENES AND IMMUNITY

IL4I1 Is a Novel Regulator of M2 Macrophage Polarization That Can Inhibit T Cell Activation via L-Tryptophan and Arginine Depletion and IL-10 Production

(2015) Yinpu Yue et al.   PLoS One

IL-4-induced gene 1 maintains high Tob1 expression that contributes to TCR unresponsiveness in human T helper 17 cells

(2013) Veronica Santarlasci et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Antibacterial Properties of the Mammalian L-Amino Acid Oxidase IL4I1

(2013) Marie-Line Puiffe et al.   PLoS One

Rarity of Human T Helper 17 Cells Is due to Retinoic Acid Orphan Receptor-Dependent Mechanisms that Limit Their Expansion

(2012) Veronica Santarlasci et al.   IMMUNITY

Siglec-9 is a novel leukocyte ligand for vascular adhesion protein-1 and can be used in PET imaging of inflammation and cancer

(2011) K. Aalto et al.   BLOOD

IL4I1: an inhibitor of the CD8+ antitumor T-cell response in vivo

(2011) Fanette Lasoudris et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Indoleamine 2,3-dioxygenase is a signaling protein in long-term tolerance by dendritic cells

(2011) Maria T Pallotta et al.   NATURE IMMUNOLOGY

Germinal Center Dynamics Revealed by Multiphoton Microscopy with a Photoactivatable Fluorescent Reporter

(2010) Gabriel D. Victora et al.   CELL

Dichotomy between factors inducing the immunosuppressive enzyme IL-4-induced gene 1 (IL4I1) in B lymphocytes and mononuclear phagocytes

(2010) Jeanine Marquet et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

CXCR4 Expression Functionally Discriminates Centroblasts versus Centrocytes within Human Germinal Center B Cells

(2009) G. Caron et al.   JOURNAL OF IMMUNOLOGY

The novel immunosuppressive enzyme IL4I1 is expressed by neoplastic cells of several B-cell lymphomas and by tumor-associated macrophages

(2009) A Carbonnelle-Puscian et al.   LEUKEMIA

Stromal gene expression predicts clinical outcome in breast cancer

(2008) Greg Finak et al.   NATURE MEDICINE