Convolutional Neural Network and Bidirectional Long Short-Term Memory-Based Method for Predicting Drug–Disease Associations

GP2017, an adalimumab biosimilar: pharmacokinetic similarity to its reference medicine and pharmacokinetics comparison of different administration methods

(2019) Oliver von Richter et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

Drug repositioning through integration of prior knowledge and projections of drugs and diseases

(2019) Ping Xuan et al.   BIOINFORMATICS

Gradient Boosting Decision Tree-Based Method for Predicting Interactions Between Target Genes and Drugs

(2019) Ping Xuan et al.   Frontiers in Genetics

Predicting drug-disease associations by using similarity constrained matrix factorization

(2018) Wen Zhang et al.   BMC BIOINFORMATICS

Renovation as innovation: is repurposing the future of drug discovery research?

(2018) Arthur Neuberger et al.   DRUG DISCOVERY TODAY

Accurate Drug Repositioning through Non-tissue-Specific Core Signatures from Cancer Transcriptomes

(2018) Chi Xu et al.   Cell Reports

Deep learning of the splicing (epi)genetic code reveals a novel candidate mechanism linking histone modifications to ESC fate decision

(2017) Yungang Xu et al.   NUCLEIC ACIDS RESEARCH

Expected p-values in light of an ROC curve analysis applied to optimal multiple testing procedures

(2017) Albert Vexler et al.   STATISTICAL METHODS IN MEDICAL RESEARCH

Deep-learning: investigating deep neural networks hyper-parameters and comparison of performance to shallow methods for modeling bioactivity data

(2017) Alexios Koutsoukas et al.   Journal of Cheminformatics

Scalable Data Mining Algorithms in Computational Biology and Biomedicine

(2017) Quan Zou et al.   Biomed Research International

Drug repositioning based on comprehensive similarity measures and Bi-Random walk algorithm

(2016) Huimin Luo et al.   BIOINFORMATICS

Inferring new indications for approved drugs via random walk on drug-disease heterogenous networks

(2016) Hui Liu et al.   BMC BIOINFORMATICS

Identify bilayer modules via pseudo-3D clustering: applications to miRNA-gene bilayer networks

(2016) Yungang Xu et al.   NUCLEIC ACIDS RESEARCH

Computational and Experimental Advances in Drug Repositioning for Accelerated Therapeutic Stratification

(2015) Khader Shameer et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Drug repositioning by integrating target information through a heterogeneous network model

(2014) Wenhui Wang et al.   BIOINFORMATICS

Exploring the associations between drug side-effects and therapeutic indications

(2014) Fei Wang et al.   JOURNAL OF BIOMEDICAL INFORMATICS

SemFunSim: A New Method for Measuring Disease Similarity by Integrating Semantic and Gene Functional Association

(2014) Liang Cheng et al.   PLoS One

Inferring the soybean (Glycine max) microRNA functional network based on target gene network

(2013) Yungang Xu et al.   BIOINFORMATICS

Gaussian interaction profile kernels for predicting drug–target interaction

(2011) Twan van Laarhoven et al.   BIOINFORMATICS

Inferring the human microRNA functional similarity and functional network based on microRNA-associated diseases

(2010) Dong Wang et al.   BIOINFORMATICS

How to improve R&D productivity: the pharmaceutical industry's grand challenge

(2010) Steven M. Paul et al.   NATURE REVIEWS DRUG DISCOVERY

PubChem: a public information system for analyzing bioactivities of small molecules

(2009) Y. Wang et al.   NUCLEIC ACIDS RESEARCH