Tanshinone IIA Restores Dynamic Balance of Autophagosome/Autolysosome in Doxorubicin-Induced Cardiotoxicity via Targeting Beclin1/LAMP1

Balancing mTOR Signaling and Autophagy in the Treatment of Parkinson’s Disease

(2019) Zhou Zhu et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Autophagy and cardiac aging

(2019) Shigeki Miyamoto   CELL DEATH AND DIFFERENTIATION

Sodium Tanshinone II A Sulfonate for Coronary Heart Disease: A Systematic Review of Randomized Controlled Trials

(2018) Mei-li Yu et al.   Chinese Journal of Integrative Medicine

Tanshinone IIA protects against subclinical lipopolysaccharide induced cardiac fibrosis in mice through inhibition of NADPH oxidase

(2018) Libing Huang et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Disruption of ROCK1 gene restores autophagic flux and mitigates doxorubicin-induced cardiotoxicity

(2018) Jianjian Shi et al.   Oncotarget

Nrf2‑dependent antioxidant response mediated the protective effect of tanshinone IIA on doxorubicin‑induced cardiotoxicity

(2018) Zhaohui Guo et al.   Experimental and Therapeutic Medicine

Tanshinone IIA ameliorates apoptosis of myocardiocytes by up-regulation of miR-133 and suppression of Caspase-9

(2017) Tao Song et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

The Impact of Autophagy on Cardiovascular Senescence and Diseases

(2017) Yuichi Sasaki et al.   International Heart Journal

Autophagic dysregulation in doxorubicin cardiomyopathy

(2017) Jordan J. Bartlett et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

MiRNA-30e mediated cardioprotection of ACE2 in rats with Doxorubicin-induced heart failure through inhibiting cardiomyocytes autophagy

(2017) Lei Lai et al.   LIFE SCIENCES

Anti-atherosclerotic effects of pravastatin in brachiocephalic artery in comparison with en face aorta and aortic roots in ApoE/LDLR−/− mice

(2017) Renata B. Kostogrys et al.   Pharmacological Reports

Protective Effects of Dexrazoxane against Doxorubicin-Induced Cardiotoxicity: A Metabolomic Study

(2017) Yang QuanJun et al.   PLoS One

TFEB ameliorates the impairment of the autophagy-lysosome pathway in neurons induced by doxorubicin

(2016) Jose Felix Moruno-Manchon et al.   Aging-US

PI3K/Akt/mTOR activation by suppression of ELK3 mediates chemosensitivity of MDA-MB-231 cells to doxorubicin by inhibiting autophagy

(2016) Ji-Hoon Park et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Doxorubicin impairs cardiomyocyte viability by suppressing transcription factor EB expression and disrupting autophagy

(2016) J. J. Bartlett et al.   BIOCHEMICAL JOURNAL

Reduction of atrial fibrillation by Tanshinone IIA in chronic heart failure

(2016) Zhifeng He et al.   BIOMEDICINE & PHARMACOTHERAPY

Doxorubicin Blocks Cardiomyocyte Autophagic Flux by Inhibiting Lysosome AcidificationCLINICAL PERSPECTIVE

(2016) Dan L. Li et al.   CIRCULATION

Elevated Cardiac Enzymes in Hypertrophic Cardiomyopathy Patients With Heart Failure　– A 20-Year Prospective Follow-up Study –

(2016) Mareomi Hamada et al.   CIRCULATION JOURNAL

TFEB at a glance

(2016) Gennaro Napolitano et al.   JOURNAL OF CELL SCIENCE

Regulation of autophagy by Beclin 1 in the heart

(2016) Yasuhiro Maejima et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Basal autophagy protects cardiomyocytes from doxorubicin-induced toxicity

(2016) Marcela Pizarro et al.   TOXICOLOGY

Experimental design and analysis and their reporting: new guidance for publication in BJP

(2015) Michael J Curtis et al.   BRITISH JOURNAL OF PHARMACOLOGY

Therapeutic Targeting of Autophagy: Potential and Concerns in Treating Cardiovascular Disease

(2015) A. M. Orogo et al.   CIRCULATION RESEARCH

Cardioprotection and Second Malignant Neoplasms Associated With Dexrazoxane in Children Receiving Anthracycline Chemotherapy: A Systematic Review and Meta-Analysis

(2015) Furqan Shaikh et al.   JNCI-Journal of the National Cancer Institute

Cardioprotection and Second Malignant Neoplasms Associated With Dexrazoxane in Children Receiving Anthracycline Chemotherapy: A Systematic Review and Meta-Analysis

(2015) Furqan Shaikh et al.   JNCI-Journal of the National Cancer Institute

Ghrelin inhibits doxorubicin cardiotoxicity by inhibiting excessive autophagy through AMPK and p38-MAPK

(2014) Xue Wang et al.   BIOCHEMICAL PHARMACOLOGY

Sodium tanshinone IIA sulfonate and sodium danshensu open the placental barrier through down-regulation of placental P-glycoprotein in mice: Implications in the transplacental digoxin treatment for fetal heart failure

(2014) Chuan Wang et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Aldehyde dehydrogenase 2 ameliorates doxorubicin-induced myocardial dysfunction through detoxification of 4-HNE and suppression of autophagy

(2014) Aijun Sun et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Enhancement of Doxorubicin Cytotoxicity by Tanshinone IIA in HepG2 Human Hepatoma Cells

(2014) Shidong Kan et al.   PLANTA MEDICA

Protein-releasing polymeric scaffolds induce fibrochondrocytic differentiation of endogenous cells for knee meniscus regeneration in sheep

(2014) C. H. Lee et al.   Science Translational Medicine

Activation of lysosomal function in the course of autophagy via mTORC1 suppression and autophagosome-lysosome fusion

(2013) Jing Zhou et al.   CELL RESEARCH

Signals from the lysosome: a control centre for cellular clearance and energy metabolism

(2013) Carmine Settembre et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Mito-Tempol and Dexrazoxane Exhibit Cardioprotective and Chemotherapeutic Effects through Specific Protein Oxidation and Autophagy in a Syngeneic Breast Tumor Preclinical Model

(2013) Jennifer S. Dickey et al.   PLoS One

Identification of ROCK1 kinase as a critical regulator of Beclin1-mediated autophagy during metabolic stress

(2013) Aditi U. Gurkar et al.   Nature Communications

MTORC1 functions as a transcriptional regulator of autophagy by preventing nuclear transport of TFEB

(2012) Jose A. Martina et al.   Autophagy

A lysosome-to-nucleus signalling mechanism senses and regulates the lysosome via mTOR and TFEB

(2012) Carmine Settembre et al.   EMBO JOURNAL

Proteomic Assessment of Tanshinone II A Sodium Sulfonate on Doxorubicin Induced Nephropathy

(2011) Xuan Liu et al.   AMERICAN JOURNAL OF CHINESE MEDICINE

Tanshinone IIA prevents doxorubicin-induced cardiomyocyte apoptosis through Akt-dependent pathway

(2010) Hong-Jye Hong et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Tanshinone IIA sodium sulfonate protects against cardiotoxicity induced by doxorubicin in vitro and in vivo

(2009) Baohong Jiang et al.   FOOD AND CHEMICAL TOXICOLOGY