Inhibition of protein phosphatase 1 stimulates noncanonical ER stress eIF2α activation to enhance fisetin-induced chemosensitivity in HDAC inhibitor-resistant hepatocellular carcinoma cells

Combination Therapy of Chloroquine and C2-Ceramide Enhances Cytotoxicity in Lung Cancer H460 and H1299 Cells

(2019) Han-Lin Chou et al.   Cancers

Modification of Epigenetic Histone Acetylation in Hepatocellular Carcinoma

(2018) Kwei-Yan Liu et al.   Cancers

Histone deacetylase inhibitors in hepatocellular carcinoma: A therapeutic perspective

(2018) Diamantis I. Tsilimigras et al.   SURGICAL ONCOLOGY-OXFORD

Fisetin-induced apoptosis of human oral cancer SCC-4 cells through reactive oxygen species production, endoplasmic reticulum stress, caspase-, and mitochondria-dependent signaling pathways

(2017) Chen-Hsuan Su et al.   ENVIRONMENTAL TOXICOLOGY

Association of Provider Specialty and Multidisciplinary Care With Hepatocellular Carcinoma Treatment and Mortality

(2017) Marina Serper et al.   GASTROENTEROLOGY

Correlation of Chitinase 3-Like 1 Single Nucleotide Polymorphisms with Hepatocellular Carcinoma in Taiwan

(2017) Wayne Shih-Wei Huang et al.   International Journal of Medical Sciences

Role of Protein Phosphatase 1 in Angiogenesis and Odontoblastic Differentiation of Human Dental Pulp Cells

(2017) Ji-Youn Kim et al.   JOURNAL OF ENDODONTICS

Combining drugs and extending treatment — a PFS end point is not sufficient

(2017) Bishal Gyawali et al.   Nature Reviews Clinical Oncology

Autophagy inhibits C2-ceramide-mediated cell death by decreasing the reactive oxygen species levels in SH-SY5Y cells

(2017) Chenghe Fan et al.   NEUROSCIENCE LETTERS

Protein phosphatase 1 regulatory subunit 1A in ewing sarcoma tumorigenesis and metastasis

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Thymoquinone suppresses migration of LoVo human colon cancer cells by reducing prostaglandin E2 induced COX-2 activation

(2017) Hsi-Hsien Hsu et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Polycystin-1 inhibits eIF2α phosphorylation and cell apoptosis through a PKR-eIF2α pathway

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Targeted redox inhibition of protein phosphatase 1 by Nox4 regulates eIF2 -mediated stress signaling

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Taiwanin E inhibits cell migration in human LoVo colon cancer cells by suppressing MMP-2/9 expression via p38 MAPK pathway

(2016) Hsi-Hsien Hsu et al.   ENVIRONMENTAL TOXICOLOGY

Global, regional, and national life expectancy, all-cause mortality, and cause-specific mortality for 249 causes of death, 1980–2015: a systematic analysis for the Global Burden of Disease Study 2015

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Down-regulation of β-catenin and the associated migration ability by Taiwanin C in arecoline and 4-NQO-induced oral cancer cells via GSK-3β activation

(2016) Cheng-Hong Hsieh et al.   MOLECULAR CARCINOGENESIS

Phosphorylation of cofilin-1 by ERK confers HDAC inhibitor resistance in hepatocellular carcinoma cells via decreased ROS-mediated mitochondria injury

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Fisetin induces apoptosis and endoplasmic reticulum stress in human non-small cell lung cancer through inhibition of the MAPK signaling pathway

(2016) Kyoung Ah Kang et al.   TUMOR BIOLOGY

Matrine improves cognitive impairment and modulates the balance of Th17/Treg cytokines in a rat model of A β1-42 -induced Alzheimer’s disease

(2015) Yanfeng Zhang et al.   Central European Journal of Immunology

Involvement of ER stress and activation of apoptotic pathways in fisetin induced cytotoxicity in human melanoma

(2014) Deeba N. Syed et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Activation of Snail and EMT-Like Signaling via the IKKαβ/NF-κB Pathway in Apicidin-Resistant HA22T Hepatocellular Carcinoma Cells

(2014) Chuan-Chou Tu   CHINESE JOURNAL OF PHYSIOLOGY

Upregulation of forkhead box O3 transcription is involved in C2-ceramide induced apoptosis and autophagy in ovarian cancer cells in vitro

(2014) ZHISHAN JIN et al.   Molecular Medicine Reports

Apicidin-Resistant HA22T Hepatocellular Carcinoma Cells strongly activated the Wnt/β-Catenin Signaling Pathway and MMP-2 Expression via the IGF-IR/PI3K/Akt Signaling Pathway Enhancing Cell Metastatic Effect

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Effect of endoplasmic reticulum (ER) stress inducer thapsigargin on the expression of extracellular-superoxide dismutase in mouse 3T3-L1 adipocytes

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Endoplasmic Reticulum Stress–Induced Resistance to Doxorubicin Is Reversed by Paeonol Treatment in Human Hepatocellular Carcinoma Cells

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Fisetin Inhibits Migration and Invasion of Human Cervical Cancer Cells by Down-Regulating Urokinase Plasminogen Activator Expression through Suppressing the p38 MAPK-Dependent NF-κB Signaling Pathway

(2013) Ruey-Hwang Chou et al.   PLoS One

Apicidin-resistant HA22T hepatocellular carcinoma cells massively promote pro-survival capability via IGF-IR/PI3K/Akt signaling pathway activation

(2013) Hsi-Hsien Hsu et al.   TUMOR BIOLOGY

PKR negatively regulates leukemia progression in association with PP2A activation, Bcl-2 inhibition and increased apoptosis

(2013) X Cheng et al.   Blood Cancer Journal

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(2011) L S Steelman et al.   LEUKEMIA

Protein phosphatase-1 regulates Akt1 signal transduction pathway to control gene expression, cell survival and differentiation

(2010) L Xiao et al.   CELL DEATH AND DIFFERENTIATION

Serine/Threonine Phosphatases: Mechanism through Structure

(2009) Yigong Shi   CELL

Recent Advances in Cancer Therapy: An Overview

(2009) A. Urruticoechea et al.   CURRENT PHARMACEUTICAL DESIGN

Fisetin, a novel dietary flavonoid, causes apoptosis and cell cycle arrest in human prostate cancer LNCaP cells

(2008) Naghma Khan et al.   CARCINOGENESIS