Sirtuin 1-dependent resveratrol cytotoxicity and pro-differentiation activity on breast cancer cells

Therapeutic Targeting of the Warburg Effect in Pancreatic Cancer Relies on an Absence of p53 Function

(2015) N. V. Rajeshkumar et al.   CANCER RESEARCH

Resveratrol increases glycolytic flux in Saccharomyces cerevisiae via a SNF1-dependet mechanism

(2015) Luis Alberto Madrigal-Perez et al.   JOURNAL OF BIOENERGETICS AND BIOMEMBRANES

Targeting the Warburg Effect in cancer; relationships for 2-arylpyridazinones as inhibitors of the key glycolytic enzyme 6-phosphofructo-2-kinase/2,6-bisphosphatase 3 (PFKFB3)

(2014) Darby G. Brooke et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Metabolic differences in breast cancer stem cells and differentiated progeny

(2014) Erina Vlashi et al.   BREAST CANCER RESEARCH AND TREATMENT

Metabolic reprogramming orchestrates cancer stem cell properties in nasopharyngeal carcinoma

(2014) Yao-An Shen et al.   CELL CYCLE

Resveratrol Inhibits Breast Cancer Stem-Like Cells and Induces Autophagy via Suppressing Wnt/β-Catenin Signaling Pathway

(2014) Yujie Fu et al.   PLoS One

Sirtuin-3 (SIRT3), a therapeutic target with oncogenic and tumor-suppressive function in cancer

(2014) Y Chen et al.   Cell Death & Disease

Resveratrol regulates mitochondrial reactive oxygen species homeostasis through Sirt3 signaling pathway in human vascular endothelial cells

(2014) X Zhou et al.   Cell Death & Disease

High levels of SIRT1 expression enhance tumorigenesis and associate with a poor prognosis of colorectal carcinoma patients

(2014) Xiaojing Chen et al.   Scientific Reports

Resveratrol Inhibits the Growth of Gastric Cancer by Inducing G1 Phase Arrest and Senescence in a Sirt1-Dependent Manner

(2013) Qing Yang et al.   PLoS One

Evidence for a Common Mechanism of SIRT1 Regulation by Allosteric Activators

(2013) B. P. Hubbard et al.   SCIENCE

Resveratrol promotes proteasome-dependent degradation of Nanog via p53 activation and induces differentiation of glioma stem cells

(2013) Atsushi Sato et al.   Stem Cell Research

Sirtuin-2 Activity is Required for Glioma Stem Cell Proliferation Arrest but not Necrosis Induced by Resveratrol

(2013) Salwa Sayd et al.   Stem Cell Reviews and Reports

Stemness and inducing differentiation of small cell lung cancer NCI-H446 cells

(2013) Z Zhang et al.   Cell Death & Disease

SIRT1 Is Required for AMPK Activation and the Beneficial Effects of Resveratrol on Mitochondrial Function

(2012) Nathan L. Price et al.   Cell Metabolism

Metabolic Regulation in Pluripotent Stem Cells during Reprogramming and Self-Renewal

(2012) Jin Zhang et al.   Cell Stem Cell

Resveratrol-mediated apoptosis of hodgkin lymphoma cells involves SIRT1 inhibition and FOXO3a hyperacetylation

(2012) Raffaele Frazzi et al.   INTERNATIONAL JOURNAL OF CANCER

Mechanism of inhibition of mitochondrial ATP synthase by 17β−Estradiol

(2012) António J. M. Moreno et al.   JOURNAL OF BIOENERGETICS AND BIOMEMBRANES

Sirtuin 1 and Sirtuin 3: Physiological Modulators of Metabolism

(2012) Ruben Nogueiras et al.   PHYSIOLOGICAL REVIEWS

Resveratrol Inhibits Cancer Cell Metabolism by Down Regulating Pyruvate Kinase M2 via Inhibition of Mammalian Target of Rapamycin

(2012) Mohd Askandar Iqbal et al.   PLoS One

Small-Molecule Allosteric Activators of Sirtuins

(2011) David A. Sinclair et al.   Annual Review of Pharmacology and Toxicology

SIRT3 Opposes Reprogramming of Cancer Cell Metabolism through HIF1α Destabilization

(2011) Lydia W.S. Finley et al.   CANCER CELL

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

SIRT1, metabolism and cancer

(2011) John R.P. Knight et al.   CURRENT OPINION IN ONCOLOGY

Resveratrol Inhibits Growth of Orthotopic Pancreatic Tumors through Activation of FOXO Transcription Factors

(2011) Sanjit K. Roy et al.   PLoS One

Sirtuin-3 (SIRT3), a novel potential therapeutic target for oral cancer

(2010) Turki Y. Alhazzazi et al.   CANCER

Resveratrol Modulates Tumor Cell Proliferation and Protein Translation via SIRT1-Dependent AMPK Activation

(2010) Jia-Ni Lin et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Resveratrol Targets Transforming Growth Factor-β2 Signaling to Block UV-Induced Tumor Progression

(2010) Kwang Ho Kim et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Cancer Prevention and Treatment with Resveratrol: From Rodent Studies to Clinical Trials

(2009) A. Bishayee   Cancer Prevention Research

Sirtuins — novel therapeutic targets to treat age-associated diseases

(2008) Siva Lavu et al.   NATURE REVIEWS DRUG DISCOVERY

A role for the mitochondrial deacetylase Sirt3 in regulating energy homeostasis

(2008) B.-H. Ahn et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA