Development and validation of an interferon signature predicting prognosis and treatment response for glioblastoma

Immunotherapy for High Grade Gliomas: A Clinical Update and Practical Considerations for Neurosurgeons

(2019) Jacob S. Young et al.   World Neurosurgery

Tumor Evolution of Glioma-Intrinsic Gene Expression Subtypes Associates with Immunological Changes in the Microenvironment

(2018) Qianghu Wang et al.   CANCER CELL

SOCS1 and SOCS3 Target IRF7 Degradation To Suppress TLR7-Mediated Type I IFN Production of Human Plasmacytoid Dendritic Cells

(2018) Chun-Feng Yu et al.   JOURNAL OF IMMUNOLOGY

Stimulation of Interferon-Stimulated Gene 20 by Thyroid Hormone Enhances Angiogenesis in Liver Cancer

(2018) Syuan-Ling Lin et al.   NEOPLASIA

Interferon Regulatory Factor 9 Structure and Regulation

(2018) Alvin Paul et al.   Frontiers in Immunology

Tumor mutational burden is a determinant of immune-mediated survival in breast cancer

(2018) Alexandra Thomas et al.   OncoImmunology

Induction of interleukin 6 impairs the anti-HBV efficiency of IFN-α in human hepatocytes through upregulation of SOCS3

(2018) Kai Yang et al.   JOURNAL OF MEDICAL VIROLOGY

The IFN-γ/PD-L1 axis between T cells and tumor microenvironment: hints for glioma anti-PD-1/PD-L1 therapy

(2018) Jiawen Qian et al.   Journal of Neuroinflammation

STRING v11: protein–protein association networks with increased coverage, supporting functional discovery in genome-wide experimental datasets

(2018) Damian Szklarczyk et al.   NUCLEIC ACIDS RESEARCH

Regulatory NLRs Control the RLR-Mediated Type I Interferon and Inflammatory Responses in Human Dendritic Cells

(2018) Tünde Fekete et al.   Frontiers in Immunology

Mutant IDH1 regulates the tumor-associated immune system in gliomas

(2017) Nduka M. Amankulor et al.   GENES & DEVELOPMENT

Hepatic IFIT3 predicts interferon-α therapeutic response in patients of hepatocellular carcinoma

(2017) Yingyun Yang et al.   HEPATOLOGY

LPS alters the immuno-phenotype of glioma and glioma stem-like cells and induces in vivo antitumor immunity via TLR4

(2017) Sheng Han et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Severe cerebral edema following nivolumab treatment for pediatric glioblastoma: case report

(2017) Xiao Zhu et al.   Journal of Neurosurgery-Pediatrics

Interaction of IRF9 and STAT2 synergistically up-regulates IFN and PKR transcription in Ctenopharyngodon idella

(2017) Zhen Wu et al.   MOLECULAR IMMUNOLOGY

Autocrine activation of the IFN signaling pathway may promote immune escape in glioblastoma

(2017) Manuela Silginer et al.   NEURO-ONCOLOGY

Type I Interferons Modulate CD8 + T Cell Immunity to mRNA Vaccines

(2017) Ans De Beuckelaer et al.   TRENDS IN MOLECULAR MEDICINE

Tumor Interferon Signaling Regulates a Multigenic Resistance Program to Immune Checkpoint Blockade

(2016) Joseph L. Benci et al.   CELL

Combination Cancer Therapies with Immune Checkpoint Blockade: Convergence on Interferon Signaling

(2016) Andy J. Minn et al.   CELL

Gene Expression Profiling Stratifies IDH1-Mutant Glioma with Distinct Prognoses

(2016) Wen Cheng et al.   MOLECULAR NEUROBIOLOGY

GlioVis data portal for visualization and analysis of brain tumor expression datasets

(2016) Robert L. Bowman et al.   NEURO-ONCOLOGY

Bioinformatic profiling identifies an immune-related risk signature for glioblastoma

(2016) Wen Cheng et al.   NEUROLOGY

NLRC5 shields T lymphocytes from NK-cell-mediated elimination under inflammatory conditions

(2016) Kristina Ludigs et al.   Nature Communications

Molecular and Genetic Properties of Tumors Associated with Local Immune Cytolytic Activity

(2015) Michael S. Rooney et al.   CELL

Meta- and Orthogonal Integration of Influenza “OMICs” Data Defines a Role for UBR4 in Virus Budding

(2015) Shashank Tripathi et al.   Cell Host & Microbe

IFIT5 positively regulates NF-κB signaling through synergizing the recruitment of IκB kinase (IKK) to TGF-β-activated kinase 1 (TAK1)

(2015) Caishang Zheng et al.   CELLULAR SIGNALLING

The Impact of Macrophage- and Microglia-Secreted TNF  on Oncolytic HSV-1 Therapy in the Glioblastoma Tumor Microenvironment

(2015) W. H. Meisen et al.   CLINICAL CANCER RESEARCH

Periostin secreted by glioblastoma stem cells recruits M2 tumour-associated macrophages and promotes malignant growth

(2015) Wenchao Zhou et al.   NATURE CELL BIOLOGY

Robust enumeration of cell subsets from tissue expression profiles

(2015) Aaron M Newman et al.   NATURE METHODS

The epidemiology of glioma in adults: a "state of the science" review

(2015) L. L. Morgan   NEURO-ONCOLOGY

Tumour-infiltrating CD4+ and CD8+ lymphocytes as predictors of clinical outcome in glioma

(2014) S Han et al.   BRITISH JOURNAL OF CANCER

Neo-antigens predicted by tumor genome meta-analysis correlate with increased patient survival

(2014) S. D. Brown et al.   GENOME RESEARCH

Interferon-β inhibits glioma angiogenesis through downregulation of vascular endothelial growth factor and upregulation of interferon inducible protein 10

(2014) SHINGO TAKANO et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Interferon-  Induces Loss of Spherogenicity and Overcomes Therapy Resistance of Glioblastoma Stem Cells

(2014) C. Happold et al.   MOLECULAR CANCER THERAPEUTICS

Interferons and Their Stimulated Genes in the Tumor Microenvironment

(2014) HyeonJoo Cheon et al.   SEMINARS IN ONCOLOGY

GSVA: gene set variation analysis for microarray and RNA-Seq data

(2013) Sonja Hänzelmann et al.   BMC BIOINFORMATICS

Tumor-Infiltrating Lymphocytes in Glioblastoma Are Associated with Specific Genomic Alterations and Related to Transcriptional Class

(2013) W. C. Rutledge et al.   CLINICAL CANCER RESEARCH

Spatiotemporal Dynamics of Intratumoral Immune Cells Reveal the Immune Landscape in Human Cancer

(2013) Gabriela Bindea et al.   IMMUNITY

The expanding role of NLRs in antiviral immunity

(2013) Christopher Lupfer et al.   IMMUNOLOGICAL REVIEWS

Prognostic Nomogram for Intrahepatic Cholangiocarcinoma After Partial Hepatectomy

(2013) Yizhou Wang et al.   JOURNAL OF CLINICAL ONCOLOGY

Phase II Pilot Study of Intravenous High-Dose Interferon With or Without Maintenance Treatment in Melanoma at High Risk of Recurrence

(2013) Miranda J. Payne et al.   JOURNAL OF CLINICAL ONCOLOGY

Immune Heterogeneity of Glioblastoma Subtypes: Extrapolation from the Cancer Genome Atlas

(2013) T. Doucette et al.   Cancer Immunology Research

Macrophage plasticity and polarization: in vivo veritas

(2012) Antonio Sica et al.   JOURNAL OF CLINICAL INVESTIGATION

Chronic renoprotective effect of pulsatile perfusion machine RM3 and IGL-1 solution in a preclinical kidney transplantation model

(2012) Raphael Thuillier et al.   Journal of Translational Medicine

Neutrophil Degranulation and Immunosuppression in Patients with GBM: Restoration of Cellular Immune Function by Targeting Arginase I

(2011) T. R. Sippel et al.   CLINICAL CANCER RESEARCH

Direct Effects of Type I Interferons on Cells of the Immune System

(2011) S. Hervas-Stubbs et al.   CLINICAL CANCER RESEARCH

The Brustkrebs-Studien.de website for breast cancer patients: User acceptance of a German internet portal offering information on the disease and treatment options, and a clinical trials matching service

(2010) Markus Wallwiener et al.   BMC CANCER

NLRC5 Negatively Regulates the NF-κB and Type I Interferon Signaling Pathways

(2010) Jun Cui et al.   CELL

ClueGO: a Cytoscape plug-in to decipher functionally grouped gene ontology and pathway annotation networks

(2009) Gabriela Bindea et al.   BIOINFORMATICS

IFR-9/STAT2 Functional Interaction Drives Retinoic Acid-Induced Gene G Expression Independently of STAT1

(2009) Y.-J. Lou et al.   CANCER RESEARCH

IRF9 is a Key Factor for Eliciting the Antiproliferative Activity of IFN-α

(2009) Takaya Tsuno et al.   JOURNAL OF IMMUNOTHERAPY

Tumor-Targeted Interferon-α Delivery by Tie2-Expressing Monocytes Inhibits Tumor Growth and Metastasis

(2008) Michele De Palma et al.   CANCER CELL

Prognostic relevance of SOCS3 hypermethylation in patients with glioblastoma multiforme

(2008) Maurizio Martini et al.   INTERNATIONAL JOURNAL OF CANCER

Regulation of innate immunity by suppressor of cytokine signaling (SOCS) proteins

(2007) Alexander Dalpke et al.   IMMUNOBIOLOGY