Constitutively active GSK3β as a means to bolster dendritic cell functionality in the face of tumor-mediated immune suppression

TK Inhibitor Pazopanib Primes DCs by Downregulation of the β-Catenin Pathway

(2018) Ilaria Grazia Zizzari et al.   Cancer Immunology Research

Advances in immunotherapy for the treatment of glioblastoma

(2016) Amanda Tivnan et al.   JOURNAL OF NEURO-ONCOLOGY

Mechanisms of immune evasion and current status of checkpoint inhibitors in non-small cell lung cancer

(2016) Angel Qin et al.   Cancer Medicine

Melanoma-intrinsic β-catenin signalling prevents anti-tumour immunity

(2015) Stefani Spranger et al.   NATURE

TLR2-Dependent Activation of β-Catenin Pathway in Dendritic Cells Induces Regulatory Responses and Attenuates Autoimmune Inflammation

(2014) Indumathi Manoharan et al.   JOURNAL OF IMMUNOLOGY

Targeting dendritic cells--why bother?

(2013) M. Kreutz et al.   BLOOD

Fas Signal Promotes the Immunosuppressive Function of Regulatory Dendritic Cells via the ERK/β-Catenin Pathway

(2013) Cheng Qian et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

IL-10 Conditioning of Human Skin Affects the Distribution of Migratory Dendritic Cell Subsets and Functional T Cell Differentiation

(2013) Jelle J. Lindenberg et al.   PLoS One

Functional characterization of a STAT3-dependent dendritic cell-derived CD14+cell population arising upon IL-10-driven maturation

(2013) Jelle J. Lindenberg et al.   OncoImmunology

Decisions About Dendritic Cells: Past, Present, and Future

(2012) Ralph M. Steinman   Annual Review of Immunology

Kinome profiling of non-canonical TRAIL signaling reveals RIP1-Src-STAT3-dependent invasion in resistant non-small cell lung cancer cells

(2012) K. Azijli et al.   JOURNAL OF CELL SCIENCE

CD40-targeted adenoviral cancer vaccines: the long and winding road to the clinic

(2012) Basav N. Hangalapura et al.   JOURNAL OF GENE MEDICINE

Role of glycogen synthase kinase-3 beta in the inflammatory response caused by bacterial pathogens

(2012) Ricarda Cortés-Vieyra et al.   Journal of Inflammation-London

Tumor-mediated inhibition of human dendritic cell differentiation and function is consistently counteracted by combined p38 MAPK and STAT3 inhibition

(2012) Dinja Oosterhoff et al.   OncoImmunology

Dendritic cell maturation occurs through the inhibition of GSK-3β

(2011) Alessandro Alessandrini et al.   CELLULAR IMMUNOLOGY

Glioblastoma-induced inhibition of Langerhans cell differentiation from CD34+precursors is mediated by IL-6 but unaffected by JAK2/STAT3 inhibition

(2011) Hester van Cruijsen et al.   Immunotherapy

Wnt5a Skews Dendritic Cell Differentiation to an Unconventional Phenotype with Tolerogenic Features

(2011) Jaris Valencia et al.   JOURNAL OF IMMUNOLOGY

A New Subset of CD103+CD8 + Dendritic Cells in the Small Intestine Expresses TLR3, TLR7, and TLR9 and Induces Th1 Response and CTL Activity

(2011) K. Fujimoto et al.   JOURNAL OF IMMUNOLOGY

Inflammation meets cancer, with NF-κB as the matchmaker

(2011) Yinon Ben-Neriah et al.   NATURE IMMUNOLOGY

CD40 engagement on dendritic cells induces cyclooxygenase-2 and EP2 receptor via p38 and ERK MAPKs

(2010) Hedi Harizi et al.   IMMUNOLOGY AND CELL BIOLOGY

The Role of Glycogen Synthase Kinase 3 in Regulating IFN- -Mediated IL-10 Production

(2010) H. Wang et al.   JOURNAL OF IMMUNOLOGY

Notch and Wingless Signaling Cooperate in Regulation of Dendritic Cell Differentiation

(2009) Jie Zhou et al.   IMMUNITY

CD11c+CD8 + Dendritic Cells Promote Protective Immunity to Respiratory Infection with Bordetella pertussis

(2009) P. J. Dunne et al.   JOURNAL OF IMMUNOLOGY

Comparison of Peptide Array Substrate Phosphorylation of c-Raf and Mitogen Activated Protein Kinase Kinase Kinase 8

(2009) Kaushal Parikh et al.   PLoS One

p38 mitogen-activated protein kinase regulates canonical Wnt- -catenin signaling by inactivation of GSK3 

(2008) R. K. Bikkavilli et al.   JOURNAL OF CELL SCIENCE

Human dendritic cell line models for DC differentiation and clinical DC vaccination studies

(2008) Saskia J. A. M. Santegoets et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Cancer-related inflammation

(2008) Alberto Mantovani et al.   NATURE