Advances in immunotherapy for the treatment of glioblastoma

Genomic and Transcriptomic Features of Response to Anti-PD-1 Therapy in Metastatic Melanoma

(2016) Willy Hugo et al.   CELL

Human glioblastoma-associated microglia/monocytes express a distinct RNA profile compared to human control and murine samples

(2016) Frank Szulzewsky et al.   GLIA

Resistance Mechanisms to Immune-Checkpoint Blockade in Cancer: Tumor-Intrinsic and -Extrinsic Factors

(2016) Jonathan M. Pitt et al.   IMMUNITY

Aberrant Notch signaling in glioblastoma stem cells contributes to tumor recurrence and invasion

(2016) Jian-Bo Yu et al.   Molecular Medicine Reports

Distinct Transcriptional Programs Control Cross-Priming in Classical and Monocyte-Derived Dendritic Cells

(2016) Carlos G. Briseño et al.   Cell Reports

Anti-CD47 Treatment Stimulates Phagocytosis of Glioblastoma by M1 and M2 Polarized Macrophages and Promotes M1 Polarized Macrophages In Vivo

(2016) Michael Zhang et al.   PLoS One

Immunotherapy response assessment in neuro-oncology: a report of the RANO working group

(2015) Hideho Okada et al.   LANCET ONCOLOGY

Tetanus toxoid and CCL3 improve dendritic cell vaccines in mice and glioblastoma patients

(2015) Duane A. Mitchell et al.   NATURE

Outcomes of the ACT III Study

(2015) Benjamin M. Zussman et al.   NEUROSURGERY

Clinical development of galunisertib (LY2157299 monohydrate), a small molecule inhibitor of transforming growth factor-beta signaling pathway

(2015) Michael Lahn et al.   Drug Design Development and Therapy

Potential protective immunogenicity of tetanus toxoid, diphtheria toxoid and Cross Reacting Material 197 (CRM197) when used as carrier proteins in glycoconjugates

(2015) Michael Bröker   Human Vaccines & Immunotherapeutics

Pitfalls in the Neuroimaging of Glioblastoma in the Era of Antiangiogenic and Immuno/Targeted Therapy – Detecting Illusive Disease, Defining Response

(2015) Raymond Y. Huang et al.   Frontiers in Neurology

Dual targeting of glioblastoma with chimeric antigen receptor-engineered natural killer cells overcomes heterogeneity of target antigen expression and enhances antitumor activity and survival

(2015) Sabrina Genßler et al.   OncoImmunology

Autologous HER2 CMV bispecific CAR T cells are safe and demonstrate clinical benefit for glioblastoma in a Phase I trial.

(2015) Nabil Ahmed et al.   Journal for ImmunoTherapy of Cancer

Identification of a 6-Cytokine Prognostic Signature in Patients with Primary Glioblastoma Harboring M2 Microglia/Macrophage Phenotype Relevance

(2015) Jinquan Cai et al.   PLoS One

CD103+ Dendritic Cells Producing Interleukin-12 in Anticancer Immunosurveillance

(2014) Laurence Zitvogel et al.   CANCER CELL

Dendritic Cell-Based Vaccine for the Treatment of Malignant Glioma: A Systematic Review

(2014) Xuan Wang et al.   CANCER INVESTIGATION

Association of PD-1, PD-1 Ligands, and Other Features of the Tumor Immune Microenvironment with Response to Anti-PD-1 Therapy

(2014) J. M. Taube et al.   CLINICAL CANCER RESEARCH

Macrophage Activation and Polarization: Nomenclature and Experimental Guidelines

(2014) Peter J. Murray et al.   IMMUNITY

Principles of T2*-weighted dynamic susceptibility contrast MRI technique in brain tumor imaging

(2014) Mark S. Shiroishi et al.   JOURNAL OF MAGNETIC RESONANCE IMAGING

Peptide vaccines for the treatment of glioblastoma

(2014) Adam M. Swartz et al.   JOURNAL OF NEURO-ONCOLOGY

In vivo discovery of immunotherapy targets in the tumour microenvironment

(2014) Penghui Zhou et al.   NATURE

Interleukin-13 Receptor Alpha 2-Targeted Glioblastoma Immunotherapy

(2014) Sadhak Sengupta et al.   Biomed Research International

Immunovirotherapy for the treatment of glioblastoma

(2014) Tooba A Cheema et al.   OncoImmunology

Exomics and immunogenics

(2014) Stéphane Champiat et al.   OncoImmunology

A clinical trial of CTLA-4 blockade with tremelimumab in patients with hepatocellular carcinoma and chronic hepatitis C

(2013) Bruno Sangro et al.   JOURNAL OF HEPATOLOGY

The microglial activation state regulates migration and roles of matrix-dissolving enzymes for invasion

(2013) Starlee Lively et al.   Journal of Neuroinflammation

YB-1 dependent oncolytic adenovirus efficiently inhibits tumor growth of glioma cancer stem like cells

(2013) Klaus Mantwill et al.   Journal of Translational Medicine

T11TS inhibits glioma angiogenesis by modulation of MMPs, TIMPs, with related integrin αv and TGF-β1 expressions

(2013) Manoj Kumar Singh et al.   TUMOR BIOLOGY

Phase I trial of a multi-epitope-pulsed dendritic cell vaccine for patients with newly diagnosed glioblastoma

(2012) Surasak Phuphanich et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Viral Vector-Based Therapeutic Cancer Vaccines

(2011) Cecilia Larocca et al.   CANCER JOURNAL

Application of Novel Response/Progression Measures for Surgically Delivered Therapies for Gliomas

(2011) Michael A. Vogelbaum et al.   NEUROSURGERY

Osteopontin is up-regulated and associated with neutrophil and macrophage infiltration in glioblastoma

(2010) Nadia A. Atai et al.   IMMUNOLOGY

Inhibition of Necl-5 (CD155/PVR) reduces glioblastoma dispersal and decreases MMP-2 expression and activity

(2010) Brian M. Enloe et al.   JOURNAL OF NEURO-ONCOLOGY

Distinct effects of human glioblastoma immunoregulatory molecules programmed cell death ligand-1 (PDL-1) and indoleamine 2,3-dioxygenase (IDO) on tumour-specific T cell functions

(2010) Tony Avril et al.   JOURNAL OF NEUROIMMUNOLOGY

Targeted therapy for high-grade glioma with the TGF- 2 inhibitor trabedersen: results of a randomized and controlled phase IIb study

(2010) U. Bogdahn et al.   NEURO-ONCOLOGY

NK Cells Recognize and Kill Human Glioblastoma Cells with Stem Cell-Like Properties

(2009) R. Castriconi et al.   JOURNAL OF IMMUNOLOGY

Intralesional Lymphokine-activated Killer Cells as Adjuvant Therapy for Primary Glioblastoma

(2009) Robert Owen Dillman et al.   JOURNAL OF IMMUNOTHERAPY

Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial

(2009) Roger Stupp et al.   LANCET ONCOLOGY

Oncolytic adenovirus retargeted to Delta-EGFR induces selective antiglioma activity

(2008) Y Piao et al.   CANCER GENE THERAPY

Disease progression or pseudoprogression after concomitant radiochemotherapy treatment: Pitfalls in neurooncology

(2008) Alba A. Brandes et al.   NEURO-ONCOLOGY

Regulatory T cells and the PD-L1/PD-1 pathway mediate immune suppression in malignant human brain tumors

(2008) Joannes F.M. Jacobs et al.   NEURO-ONCOLOGY