The Fluctuations of Leukocytes and Circulating Cytokines in Septic Humanized Mice Vary With Outcome

Hydrocortisone, Ascorbic acid and Thiamine (HAT) Therapy Decreases Oxidative Stress, Improves Cardiovascular Function and Improves Survival in Murine Sepsis

(2019) John Kim et al.   SHOCK

Humanized Mice as Unique Tools for Human-Specific Studies

(2018) Kylie Su Mei Yong et al.   ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS

A Hitchhiker's guide to humanized mice: new pathways to studying viral infections

(2018) Jessica Katy Skelton et al.   IMMUNOLOGY

Delayed activation of PPAR-β/δ improves long-term survival in mouse sepsis: effects on organ inflammation and coagulation

(2018) Daniel Busch et al.   Innate Immunity

Part I

(2018) Basilia Zingarelli et al.   SHOCK

Minimum Quality Threshold in Pre-Clinical Sepsis Studies (Mqtipss)

(2018) Marcin F. Osuchowski et al.   SHOCK

Splenectomy modulates early immuno-inflammatory responses to trauma-hemorrhage and protects mice against secondary sepsis

(2018) S. Drechsler et al.   Scientific Reports

Murine Models of Sepsis and Trauma: Can We Bridge the Gap?

(2017) Julie A. Stortz et al.   ILAR JOURNAL

Incidence and Trends of Sepsis in US Hospitals Using Clinical vs Claims Data, 2009-2014

(2017) Chanu Rhee et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Mitochondria-Targeted Antioxidants SkQ1 and MitoTEMPO Failed to Exert a Long-Term Beneficial Effect in Murine Polymicrobial Sepsis

(2017) Pia Rademann et al.   Oxidative Medicine and Cellular Longevity

The clinical and immunological performance of 28 days survival model of cecal ligation and puncture in humanized mice

(2017) Krzysztof Laudanski et al.   PLoS One

Humanized Mouse Models for Human Immunodeficiency Virus Infection

(2017) Matthew D. Marsden et al.   Annual Review of Virology

Assessment of Global Incidence and Mortality of Hospital-treated Sepsis. Current Estimates and Limitations

(2016) Carolin Fleischmann et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Humanized Mice Exhibit Increased Susceptibility toStaphylococcus aureusPneumonia

(2016) Alice Prince et al.   JOURNAL OF INFECTIOUS DISEASES

The Early Expression of HLA-DR and CD64 Myeloid Markers Is Specifically Compartmentalized in the Blood and Lungs of Patients with Septic Shock

(2016) Tomasz Skirecki et al.   MEDIATORS OF INFLAMMATION

Staphylococcus aureusInfection in Humanized Mice: A New Model to Study Pathogenicity Associated With Human Immune Response

(2015) Janin Knop et al.   JOURNAL OF INFECTIOUS DISEASES

Early severe impairment of hematopoietic stem and progenitor cells from the bone marrow caused by CLP sepsis and endotoxemia in a humanized mice model

(2015) Tomasz Skirecki et al.   Stem Cell Research & Therapy

Systemic inhibition and liver-specific over-expression of PAI-1 failed to improve survival in all-inclusive populations or homogenous cohorts of CLP mice

(2014) P. Raeven et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Abandon the Mouse Research Ship? Not Just Yet!

(2014) Marcin F. Osuchowski et al.   SHOCK

Why have clinical trials in sepsis failed?

(2014) John C. Marshall   TRENDS IN MOLECULAR MEDICINE

Infection-Induced Changes in Hematopoiesis

(2013) A. G. Zaretsky et al.   JOURNAL OF IMMUNOLOGY

Sepsis Immunopathology: Perspectives of Monitoring and Modulation of the Immune Disturbances

(2012) Tomasz Skirecki et al.   ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS

Monocytes derived from humanized neonatal NOD/SCID/IL2Rγnull mice are phenotypically immature and exhibit functional impairments

(2012) Christian Gille et al.   HUMAN IMMUNOLOGY

Human macrophage and dendritic cell-specific silencing of high-mobility group protein B1 ameliorates sepsis in a humanized mouse model

(2012) C. Ye et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

RIP Kinase-Dependent Necrosis Drives Lethal Systemic Inflammatory Response Syndrome

(2011) Linde Duprez et al.   IMMUNITY

Engraftment of human hematopoietic stem cells is more efficient in female NOD/SCID/IL-2Rgc-null recipients

(2010) F. Notta et al.   BLOOD

Animal research: Reporting in vivo experiments: The ARRIVE guidelines

(2010) Carol Kilkenny et al.   BRITISH JOURNAL OF PHARMACOLOGY

REPETITIVE LOW-VOLUME BLOOD SAMPLING METHOD AS A FEASIBLE MONITORING TOOL IN A MOUSE MODEL OF SEPSIS

(2010) Katrin M. Weixelbaumer et al.   SHOCK

Sepsis-induced human lymphocyte apoptosis and cytokine production in “humanized” mice

(2009) Jacqueline Unsinger et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Humanized Mice Show Clinical Signs of Dengue Fever according to Infecting Virus Genotype

(2009) J. Mota et al.   JOURNAL OF VIROLOGY

Differential Role for CD80 and CD86 in the Regulation of the Innate Immune Response in Murine Polymicrobial Sepsis

(2009) Anna Nolan et al.   PLoS One

CD40 and CD80/86 Act Synergistically to Regulate Inflammation and Mortality in Polymicrobial Sepsis

(2007) Anna Nolan et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE