Distinct Roles of α7 nAChRs in Antigen-Presenting Cells and CD4+ T Cells in the Regulation of T Cell Differentiation

α7 nicotinic acetylcholine receptors are involved in suppression of the antibody immune response

(2018) Lyudmyla Koval et al.   JOURNAL OF NEUROIMMUNOLOGY

Physiological functions of the cholinergic system in immune cells

(2017) Takeshi Fujii et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Acetylcholine released from T cells regulates intracellular Ca 2+ , IL-2 secretion and T cell proliferation through nicotinic acetylcholine receptor

(2017) Masato Mashimo et al.   LIFE SCIENCES

Cholinergic modulation of the immune system presents new approaches for treating inflammation

(2017) Donald B. Hoover   PHARMACOLOGY & THERAPEUTICS

Expression and Function of the Cholinergic System in Immune Cells

(2017) Takeshi Fujii et al.   Frontiers in Immunology

Follicular Helper T Cells

(2016) Carola G. Vinuesa et al.   Annual Review of Immunology

Non-neuronal cholinergic system in regulation of immune function with a focus on α7 nAChRs

(2015) Koichiro Kawashima et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Unknown

(2015) William Hanes et al.   MOLECULAR MEDICINE

Mouse Naïve CD4+ T Cell Isolation and In vitro Differentiation into T Cell Subsets

(2015) Stephanie Flaherty et al.   Jove-Journal of Visualized Experiments

Transcription Factor STAT3 and Type I Interferons Are Corepressive Insulators for Differentiation of Follicular Helper and T Helper 1 Cells

(2014) John P. Ray et al.   IMMUNITY

STAT3, STAT4, NFATc1, and CTCF Regulate PD-1 through Multiple Novel Regulatory Regions in Murine T Cells

(2014) J. W. Austin et al.   JOURNAL OF IMMUNOLOGY

Unknown

(2014) Ravikumar Sitapara et al.   MOLECULAR MEDICINE

Neuronal and nonneuronal cholinergic structures in the mouse gastrointestinal tract and spleen

(2013) Laurent Gautron et al.   JOURNAL OF COMPARATIVE NEUROLOGY

SLURP-1, an endogenous α7 nicotinic acetylcholine receptor allosteric ligand, is expressed in CD205+ dendritic cells in human tonsils and potentiates lymphocytic cholinergic activity

(2013) Takeshi Fujii et al.   JOURNAL OF NEUROIMMUNOLOGY

Lymphocyte-derived ACh regulates local innate but not adaptive immunity

(2013) Colin Reardon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Allergic Airway Inflammation in Mice Deficient for the Antigen-Processing Protease Cathepsin E

(2012) Carolin Pilzner et al.   INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY

CAR/FoxP3-engineered T regulatory cells target the CNS and suppress EAE upon intranasal delivery

(2012) Moa Fransson et al.   Journal of Neuroinflammation

Critical roles of acetylcholine and the muscarinic and nicotinic acetylcholine receptors in the regulation of immune function

(2012) Koichiro Kawashima et al.   LIFE SCIENCES

Regulatory mechanisms of acetylcholine synthesis and release by T cells

(2012) Takeshi Fujii et al.   LIFE SCIENCES

Modulation of inflammatory pathways by the immune cholinergic system

(2011) Eran Nizri et al.   AMINO ACIDS

Plasticity of the murine spleen T-cell cholinergic receptors and their role in in vitro differentiation of naïve CD4 T cells toward the Th1, Th2 and Th17 lineages

(2011) J Qian et al.   GENES AND IMMUNITY

The Transcription Factor STAT3 Is Required for T Helper 2 Cell Development

(2011) Gretta L. Stritesky et al.   IMMUNITY

Cytokine-Induced Alterations of  7 Nicotinic Receptor in Colonic CD4 T Cells Mediate Dichotomous Response to Nicotine in Murine Models of Th1/Th17- versus Th2-Mediated Colitis

(2011) V. Galitovskiy et al.   JOURNAL OF IMMUNOLOGY

IL-21 and IL-6 Are Critical for Different Aspects of B Cell Immunity and Redundantly Induce Optimal Follicular Helper CD4 T Cell (Tfh) Differentiation

(2011) Danelle Eto et al.   PLoS One

Acetylcholine-Synthesizing T Cells Relay Neural Signals in a Vagus Nerve Circuit

(2011) M. Rosas-Ballina et al.   SCIENCE

Upregulation of nuclear factor-κB expression by SLURP-1 is mediated by α7-nicotinic acetylcholine receptor and involves both ionic events and activation of protein kinases

(2010) Alexander I. Chernyavsky et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Differential involvement of α4β2, α7 and α9α10 nicotinic acetylcholine receptors in B lymphocyte activation in vitro

(2010) Lyudmyla Koval et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Activation of the Cholinergic Anti-Inflammatory System by Nicotine Attenuates Neuroinflammation via Suppression of Th1 and Th17 Responses

(2009) E. Nizri et al.   JOURNAL OF IMMUNOLOGY

CD4+ Regulatory T Cells Control TH17 Responses in a Stat3-Dependent Manner

(2009) A. Chaudhry et al.   SCIENCE

Interleukin-6/STAT3 signaling regulates the ability of naive T cells to acquire B-cell help capacities

(2008) F. Eddahri et al.   BLOOD

Cytokine Signaling Modules in Inflammatory Responses

(2008) John J. O'Shea et al.   IMMUNITY