The Long Pentraxin PTX3 as a Humoral Innate Immunity Functional Player and Biomarker of Infections and Sepsis

Pentraxin-3 Predicts Short- and Mid-term Mortality in Patients with Sepsis and Septic Shock During Intensive Care Treatment

(2018) Sonja Hamed et al.   Clinical Laboratory

Pentraxin 3 in bronchoalveolar lavage fluid and plasma in non-neutropenic patients with pulmonary aspergillosis

(2018) H. Li et al.   CLINICAL MICROBIOLOGY AND INFECTION

Pentraxin-3 polymorphisms and invasive mold infections in acute leukemia patients with intensive chemotherapy

(2018) Anne-Sophie Brunel et al.   HAEMATOLOGICA

Pentraxin-3 as a marker of sepsis severity and predictor of mortality outcomes: A systematic review and meta-analysis

(2018) Yee Ting Lee et al.   JOURNAL OF INFECTION

Sepsis and septic shock

(2018) Maurizio Cecconi et al.   LANCET

PTX3, a Humoral Pattern Recognition Molecule, in Innate Immunity, Tissue Repair, and Cancer

(2018) Cecilia Garlanda et al.   PHYSIOLOGICAL REVIEWS

Pentraxin-3 polymorphisms and invasive mold infections in acute leukemia patients with intensive chemotherapy

(2018) Anne-Sophie Brunel et al.   HAEMATOLOGICA

Role of a fluid-phase PRR in fighting an intracellular pathogen: PTX3 in Shigella infection

(2018) Valeria Ciancarella et al.   PLoS Pathogens

Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock: 2016

(2017) Andrew Rhodes et al.   INTENSIVE CARE MEDICINE

Pentraxin 3 levels in bronchoalveolar lavage fluid of lung transplant recipients with invasive aspergillosis

(2017) Dima Kabbani et al.   JOURNAL OF HEART AND LUNG TRANSPLANTATION

Serum pentraxin-3 and tumor necrosis factor-like weak inducer of apoptosis (TWEAK) predict severity of infections in acute decompensated cirrhotic patients

(2017) Wen-Chien Fan et al.   JOURNAL OF MICROBIOLOGY IMMUNOLOGY AND INFECTION

Infectious Complications and Immune/Inflammatory Response in Cardiogenic Shock Patients

(2017) Jiri Parenica et al.   SHOCK

Long Pentraxin 3 as a Predictive Marker of Mortality in Severe Septic Patients Who Received Successful Early Goal-Directed Therapy

(2017) Sun Bean Kim et al.   YONSEI MEDICAL JOURNAL

Pentraxin-3, procalcitonin and lactate as prognostic markers in patients with sepsis and septic shock

(2017) Chenggong Hu et al.   Oncotarget

Investigating the role of pentraxin 3 as a biomarker for bacterial infection in subjects with COPD

(2017) Samantha J Thulborn et al.   International Journal of Chronic Obstructive Pulmonary Disease

Pentraxin 3 in patients with severe sepsis or shock: the ALBIOS trial

(2016) Pietro Caironi et al.   EUROPEAN JOURNAL OF CLINICAL INVESTIGATION

The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3)

(2016) Mervyn Singer et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

The soluble pattern recognition receptor PTX3 links humoral innate and adaptive immune responses by helping marginal zone B cells

(2016) Alejo Chorny et al.   JOURNAL OF EXPERIMENTAL MEDICINE

PTX3 Is an Extrinsic Oncosuppressor Regulating Complement-Dependent Inflammation in Cancer

(2015) Eduardo Bonavita et al.   CELL

PTX3Polymorphisms and Invasive Mold Infections After Solid Organ Transplant: Figure 1.

(2015) Agnieszka Wójtowicz et al.   CLINICAL INFECTIOUS DISEASES

PTX3-Based Genetic Testing for Risk of Aspergillosis After Lung Transplant: Table 1.

(2015) Cristina Cunha et al.   CLINICAL INFECTIOUS DISEASES

Differential expression of pentraxin 3 in neutrophils

(2015) Olga Razvina et al.   EXPERIMENTAL AND MOLECULAR PATHOLOGY

Prognostic and diagnostic potential of local and circulating levels of pentraxin 3 in lung cancer patients

(2015) Maurizio Infante et al.   INTERNATIONAL JOURNAL OF CANCER

An acidic microenvironment sets the humoral pattern recognition molecule PTX3 in a tissue repair mode

(2015) Andrea Doni et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Sepsis: a roadmap for future research

(2015) Jonathan Cohen et al.   LANCET INFECTIOUS DISEASES

Pentraxin 3 as a clinical marker in children with lower respiratory tract infection

(2015) Hwan Soo Kim et al.   PEDIATRIC PULMONOLOGY

Role of Pentraxin 3 in Shaping Arthritogenic Alphaviral Disease: From Enhanced Viral Replication to Immunomodulation

(2015) Suan-Sin Foo et al.   PLoS Pathogens

Recognition of Neisseria meningitidis by the Long Pentraxin PTX3 and Its Role as an Endogenous Adjuvant

(2015) Barbara Bottazzi et al.   PLoS One

Efficacy of PTX3 and Posaconazole Combination in a Rat Model of Invasive Pulmonary Aspergillosis

(2014) Emanuele Marra et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

The Humoral Pattern Recognition Molecule PTX3 Is a Key Component of Innate Immunity against Urinary Tract Infection

(2014) Sébastien Jaillon et al.   IMMUNITY

Antiviral Activity of the Long Chain Pentraxin PTX3 against Influenza Viruses

(2014) P. C. Reading et al.   JOURNAL OF IMMUNOLOGY

Binding of the Long Pentraxin PTX3 to Factor H: Interacting Domains and Function in the Regulation of Complement Activation

(2014) L. Deban et al.   JOURNAL OF IMMUNOLOGY

Pentraxin 3 concentrations of the mothers with preterm premature rupture of membranes and their neonates, and early neonatal outcome

(2014) Mustafa Ali Akin et al.   Journal of Maternal-Fetal & Neonatal Medicine

Pentraxin 3 as a Prognostic Biomarker in Patients with Systemic Inflammation or Infection

(2014) Siguan Liu et al.   MEDIATORS OF INFLAMMATION

Albumin Replacement in Patients with Severe Sepsis or Septic Shock

(2014) Pietro Caironi et al.   NEW ENGLAND JOURNAL OF MEDICINE

Genetic PTX3 Deficiency and Aspergillosis in Stem-Cell Transplantation

(2014) Cristina Cunha et al.   NEW ENGLAND JOURNAL OF MEDICINE

Protective effect of the long pentraxin PTX3 against histone-mediated endothelial cell cytotoxicity in sepsis

(2014) K. Daigo et al.   Science Signaling

A Single Amino Acid Substitution in the Hemagglutinin of H3N2 Subtype Influenza A Viruses Is Associated with Resistance to the Long Pentraxin PTX3 and Enhanced Virulence in Mice

(2013) E. R. Job et al.   JOURNAL OF IMMUNOLOGY

Prototypic Long Pentraxin PTX3 Is Present in Breast Milk, Spreads in Tissues, and Protects Neonate Mice from Pseudomonas aeruginosa Lung Infection

(2013) S. Jaillon et al.   JOURNAL OF IMMUNOLOGY

Ficolin-1-PTX3 Complex Formation Promotes Clearance of Altered Self-Cells and Modulates IL-8 Production

(2013) Y. J. Ma et al.   JOURNAL OF IMMUNOLOGY

Endogenous and exogenous pentraxin-3 limits postischemic acute and chronic kidney injury

(2013) Maciej Lech et al.   KIDNEY INTERNATIONAL

Pentraxin 3 (PTX3) Is Associated with Severe Sepsis and Fatal Disease in Emergency Room Patients with Suspected Infection: A Prospective Cohort Study

(2013) Raija Uusitalo-Seppälä et al.   PLoS One

Pentraxin-3 Serum Levels Are Associated with Disease Severity and Mortality in Patients with Systemic Inflammatory Response Syndrome

(2013) Simone Bastrup-Birk et al.   PLoS One

Pentraxin-3: A novel biomarker for discriminating parapneumonic from other exudative effusions

(2013) Savas Ozsu et al.   RESPIROLOGY

Effect of PTX3 and Voriconazole Combination in a Rat Model of Invasive Pulmonary Aspergillosis

(2012) Pietro Lo Giudice et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Plasma long pentraxin 3 (PTX3) concentration is a novel marker of disease activity in patients with community-acquired pneumonia

(2012) Shang-Jyh Kao et al.   CLINICAL CHEMISTRY AND LABORATORY MEDICINE

Pentraxin-3 in chronic heart failure: the CORONA and GISSI-HF trials

(2012) Roberto Latini et al.   EUROPEAN JOURNAL OF HEART FAILURE

Pentraxin 3 in the assessment of ventilator-associated pneumonia: An early marker of severity

(2012) Qionghua Lin et al.   HEART & LUNG

Response of CFTR-Deficient Mice to Long-Term chronic Pseudomonas aeruginosa Infection and PTX3 Therapy

(2012) Moira Paroni et al.   JOURNAL OF INFECTIOUS DISEASES

The Proteomic Profile of Circulating Pentraxin 3 (PTX3) Complex in Sepsis Demonstrates the Interaction with Azurocidin 1 and Other Components of Neutrophil Extracellular Traps

(2012) Kenji Daigo et al.   MOLECULAR & CELLULAR PROTEOMICS

PTX3 as a potential endothelial dysfunction biomarker for severity of preeclampsia and IUGR

(2012) V. Cozzi et al.   PLACENTA

Influence of Pentraxin 3 (PTX3) Genetic Variants on Myocardial Infarction Risk and PTX3 Plasma Levels

(2012) Elisa Barbati et al.   PLoS One

The Therapeutic Potential of the Humoral Pattern Recognition Molecule PTX3 in Chronic Lung Infection Caused by Pseudomonas aeruginosa

(2011) F. Moalli et al.   JOURNAL OF IMMUNOLOGY

High Plasma Level of Long Pentraxin 3 (PTX3) Is Associated with Fatal Disease in Bacteremic Patients: A Prospective Cohort Study

(2011) Reetta Huttunen et al.   PLoS One

Human Pentraxin 3 Binds to the Complement Regulator C4b-Binding Protein

(2011) Anne Braunschweig et al.   PLoS One

Efficacy of PTX3 in a Rat Model of Invasive Aspergillosis

(2010) P. Lo Giudice et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Role of complement and Fc  receptors in the protective activity of the long pentraxin PTX3 against Aspergillus fumigatus

(2010) F. Moalli et al.   BLOOD

PTX3 genetic variations affect the risk of Pseudomonas aeruginosa airway colonization in cystic fibrosis patients

(2010) M Chiarini et al.   GENES AND IMMUNITY

Persisting high levels of plasma pentraxin 3 over the first days after severe sepsis and septic shock onset are associated with mortality

(2010) Tommaso Mauri et al.   INTENSIVE CARE MEDICINE

Heterocomplexes of Mannose-binding Lectin and the Pentraxins PTX3 or Serum Amyloid P Component Trigger Cross-activation of the Complement System

(2010) Ying Jie Ma et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Use of procalcitonin to reduce patients' exposure to antibiotics in intensive care units (PRORATA trial): a multicentre randomised controlled trial

(2010) Lila Bouadma et al.   LANCET

Regulation of leukocyte recruitment by the long pentraxin PTX3

(2010) Livija Deban et al.   NATURE IMMUNOLOGY

The Long Pentraxin PTX3: A Modulator of the Immunoinflammatory Response in Atherosclerosis and Cardiovascular Diseases

(2010) Giuseppe Danilo Norata et al.   TRENDS IN CARDIOVASCULAR MEDICINE

An Integrated View of Humoral Innate Immunity: Pentraxins as a Paradigm

(2009) Barbara Bottazzi et al.   Annual Review of Immunology

Determination of physiological plasma pentraxin 3 (PTX3) levels in healthy populations

(2009) Kazumi Yamasaki et al.   CLINICAL CHEMISTRY AND LABORATORY MEDICINE

Pentraxin 3 in acute respiratory distress syndrome: An early marker of severity*

(2009) Tommaso Mauri et al.   CRITICAL CARE MEDICINE

Procalcitonin assay in systemic inflammation, infection, and sepsis: Clinical utility and limitations

(2009) Kenneth L. Becker et al.   CRITICAL CARE MEDICINE

Synergy between Ficolin-2 and Pentraxin 3 Boosts Innate Immune Recognition and Complement Deposition

(2009) Ying Jie Ma et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Long pentraxin PTX3 is associated with mortality and disease severity in severe Leptospirosis

(2009) Jiri F.P. Wagenaar et al.   JOURNAL OF INFECTION

PTX3 predicts severe disease in febrile patients at the emergency department

(2009) Martijn D. de Kruif et al.   JOURNAL OF INFECTION

PTX3 as a Potential Novel Tool for the Diagnosis and Monitoring of Pulmonary Fungal Infections in Immuno-compromised Pediatric Patients

(2009) Ettore Biagi et al.   JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY

Multiple Pathogenic Roles of Microvasculature in Inflammatory Bowel Disease: A Jack of All Trades

(2008) Livija Deban et al.   AMERICAN JOURNAL OF PATHOLOGY

Structural Characterization of PTX3 Disulfide Bond Network and Its Multimeric Status in Cumulus Matrix Organization

(2008) Antonio Inforzato et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

PENTRAXIN 3 AND C-REACTIVE PROTEIN IN SEVERE MENINGOCOCCAL DISEASE

(2008) Tom Sprong et al.   SHOCK