The soluble pattern recognition receptor PTX3 links humoral innate and adaptive immune responses by helping marginal zone B cells

BAFF-secreting neutrophils drive plasma cell responses during emergency granulopoiesis

(2016) Roham Parsa et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Functional capacities of human IgM memory B cells in early inflammatory responses and secondary germinal center reactions

(2015) Marc Seifert et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Recognition of Neisseria meningitidis by the Long Pentraxin PTX3 and Its Role as an Endogenous Adjuvant

(2015) Barbara Bottazzi et al.   PLoS One

TLR Signals Induce Phagosomal MHC-I Delivery from the Endosomal Recycling Compartment to Allow Cross-Presentation

(2014) Priyanka Nair-Gupta et al.   CELL

Tissue-Specific Signals Control Reversible Program of Localization and Functional Polarization of Macrophages

(2014) Yasutaka Okabe et al.   CELL

Tissue-Resident Macrophage Enhancer Landscapes Are Shaped by the Local Microenvironment

(2014) Yonit Lavin et al.   CELL

Environment Drives Selection and Function of Enhancers Controlling Tissue-Specific Macrophage Identities

(2014) David Gosselin et al.   CELL

The Humoral Pattern Recognition Molecule PTX3 Is a Key Component of Innate Immunity against Urinary Tract Infection

(2014) Sébastien Jaillon et al.   IMMUNITY

C-Type Lectin-like Receptor LOX-1 Promotes Dendritic Cell-Mediated Class-Switched B Cell Responses

(2014) HyeMee Joo et al.   IMMUNITY

Antiviral Activity of the Long Chain Pentraxin PTX3 against Influenza Viruses

(2014) P. C. Reading et al.   JOURNAL OF IMMUNOLOGY

CpG Drives Human Transitional B Cells to Terminal Differentiation and Production of Natural Antibodies

(2014) F. Capolunghi et al.   JOURNAL OF IMMUNOLOGY

Nitric Oxide Regulates BAFF Expression and T Cell-Independent Antibody Responses

(2014) D. Giordano et al.   JOURNAL OF IMMUNOLOGY

PTX3 Binds MD-2 and Promotes TRIF-Dependent Immune Protection in Aspergillosis

(2014) Silvia Bozza et al.   JOURNAL OF IMMUNOLOGY

Innate lymphoid cells integrate stromal and immunological signals to enhance antibody production by splenic marginal zone B cells

(2014) Giuliana Magri et al.   NATURE IMMUNOLOGY

Genetic PTX3 Deficiency and Aspergillosis in Stem-Cell Transplantation

(2014) Cristina Cunha et al.   NEW ENGLAND JOURNAL OF MEDICINE

Neutrophils Contribute to Excess Serum BAFF Levels and Promote CD4+ T Cell and B Cell Responses in Lupus-Prone Mice

(2014) Christine M. Coquery et al.   PLoS One

Natural IgG antibodies provide innate protection against ficolin-opsonized bacteria

(2013) Saswati Panda et al.   EMBO JOURNAL

RNA-Seq Reveals Activation of Both Common and Cytokine-Specific Pathways following Neutrophil Priming

(2013) Helen L. Wright et al.   PLoS One

Germinal Centers

(2012) Gabriel D. Victora et al.   Annual Review of Immunology

Macrophages induce differentiation of plasma cells through CXCL10/IP-10

(2012) Wei Xu et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Genetic Defects in Severe Congenital Neutropenia: Emerging Insights into Life and Death of Human Neutrophil Granulocytes

(2011) Christoph Klein   Annual Review of Immunology

B cell–helper neutrophils stimulate the diversification and production of immunoglobulin in the marginal zone of the spleen

(2011) Irene Puga et al.   NATURE IMMUNOLOGY

Role of complement and Fc  receptors in the protective activity of the long pentraxin PTX3 against Aspergillus fumigatus

(2010) F. Moalli et al.   BLOOD

CR2+ Marginal Zone B Cell Production of Pathogenic Natural Antibodies Is C3 Independent

(2010) K. M. Woods et al.   JOURNAL OF IMMUNOLOGY

CRP is a novel ligand for the oxidized LDL receptor LOX-1

(2009) Heather H. Shih et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

An Integrated View of Humoral Innate Immunity: Pentraxins as a Paradigm

(2009) Barbara Bottazzi et al.   Annual Review of Immunology

Synergy between Ficolin-2 and Pentraxin 3 Boosts Innate Immune Recognition and Complement Deposition

(2009) Ying Jie Ma et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Novel primary immunodeficiencies revealed by the investigation of paediatric infectious diseases

(2008) Jacinta Bustamante et al.   CURRENT OPINION IN IMMUNOLOGY