CD4+ T Cells Play a Critical Role in Microbiota-Maintained Anti-HBV Immunity in a Mouse Model

OX40 stimulation and PD-L1 blockade synergistically augment HBV-specific CD4 T cells in patients with HBeAg-negative infection

(2019) Felix Johannes Jacobi et al.   JOURNAL OF HEPATOLOGY

Tumor necrosis factor: The key to hepatitis B viral clearance

(2018) I-Tsu Chyuan et al.   Cellular & Molecular Immunology

Fecal microbiota transplantation induces hepatitis B virus e-antigen (HBeAg) clearance in patients with positive HBeAg after long-term antiviral therapy

(2017) Yan-Dan Ren et al.   HEPATOLOGY

The microbiota maintain homeostasis of liver-resident γδT-17 cells in a lipid antigen/CD1d-dependent manner

(2017) Fenglei Li et al.   Nature Communications

Gut microbiota changes and chronic hepatitis C virus infection

(2017) Tomislav Preveden et al.   Expert Review of Gastroenterology & Hepatology

Combination therapy including CpG oligodeoxynucleotides and entecavir induces early viral response and enhanced inhibition of viral replication in a woodchuck model of chronic hepadnaviral infection

(2016) Zhongji Meng et al.   ANTIVIRAL RESEARCH

The microbiota in adaptive immune homeostasis and disease

(2016) Kenya Honda et al.   NATURE

Gut microbiome alterations in patients with stage 4 hepatitis C

(2016) AbdelRahman Mahmoud Aly et al.   Gut Pathogens

Kupffer Cells Support Hepatitis B Virus–Mediated CD8+T Cell Exhaustion via Hepatitis B Core Antigen–TLR2 Interactions in Mice

(2015) Min Li et al.   JOURNAL OF IMMUNOLOGY

Age-related immune clearance of hepatitis B virus infection requires the establishment of gut microbiota

(2015) Han-Hsuan Chou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Contribution of Toll-like receptors to the control of hepatitis B virus infection by initiating antiviral innate responses and promoting specific adaptive immune responses

(2014) Zhiyong Ma et al.   Cellular & Molecular Immunology

B cells as a critical node in the microbiota-host immune system network

(2014) Emma Slack et al.   IMMUNOLOGICAL REVIEWS

Regulatory B cells are induced by gut microbiota–driven interleukin-1β and interleukin-6 production

(2014) Elizabeth C Rosser et al.   NATURE MEDICINE

Toll-Like Receptor 4 and Hepatitis B Infection: Molecular Mechanisms and Pathogenesis

(2014) Mohammad Zare-Bidaki et al.   VIRAL IMMUNOLOGY

Kupffer cell-derived IL-10 plays a key role in maintaining humoral immune tolerance in hepatitis B virus-persistent mice

(2013) Long Xu et al.   HEPATOLOGY

IL-12-Based Vaccination Therapy Reverses Liver-Induced Systemic Tolerance in a Mouse Model of Hepatitis B Virus Carrier

(2013) Z. Zeng et al.   JOURNAL OF IMMUNOLOGY

Liver type I regulatory T cells suppress germinal center formation in HBV-tolerant mice

(2013) L. Xu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Toll-like Receptor and Hepatitis B Virus Clearance in Chronic Infected Patients: A Long-Term Prospective Cohort Study in Taiwan

(2012) Jia-Feng Wu et al.   JOURNAL OF INFECTIOUS DISEASES

Crosstalk between B lymphocytes, microbiota and the intestinal epithelium governs immunity versus metabolism in the gut

(2011) Natalia Shulzhenko et al.   NATURE MEDICINE

Microbiota regulates immune defense against respiratory tract influenza A virus infection

(2011) T. Ichinohe et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Microbiota innate stimulation is a prerequisite for T cell spontaneous proliferation and induction of experimental colitis

(2010) Ting Feng et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Inducible Foxp3+ regulatory T-cell development by a commensal bacterium of the intestinal microbiota

(2010) J. L. Round et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Has the Microbiota Played a Critical Role in the Evolution of the Adaptive Immune System?

(2010) Y. K. Lee et al.   SCIENCE

Induction of Colonic Regulatory T Cells by Indigenous Clostridium Species

(2010) K. Atarashi et al.   SCIENCE

The Liver as a Lymphoid Organ

(2009) Ian Nicholas Crispe   Annual Review of Immunology

Lipopolysaccharide-induced innate immune responses in primary hepatocytes downregulates woodchuck hepatitis virus replication via interferon-independent pathways

(2009) Xiaoyong Zhang et al.   CELLULAR MICROBIOLOGY

The Key Role of Segmented Filamentous Bacteria in the Coordinated Maturation of Gut Helper T Cell Responses

(2009) Valérie Gaboriau-Routhiau et al.   IMMUNITY

Commensal DNA Limits Regulatory T Cell Conversion and Is a Natural Adjuvant of Intestinal Immune Responses

(2008) Jason A. Hall et al.   IMMUNITY