Staphylococcal and Streptococcal Superantigens Trigger B7/CD28 Costimulatory Receptor Engagement to Hyperinduce Inflammatory Cytokines

Bacterial Superantigen Toxins, CD28, and Drug Development

(2018) Raymond Kaempfer   Toxins

ConSurf 2016: an improved methodology to estimate and visualize evolutionary conservation in macromolecules

(2016) Haim Ashkenazy et al.   NUCLEIC ACIDS RESEARCH

Superantigens hyperinduce inflammatory cytokines by enhancing the B7-2/CD28 costimulatory receptor interaction

(2016) Revital Levy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Two common structural motifs for TCR recognition by staphylococcal enterotoxins

(2016) Karin E. J. Rödström et al.   Scientific Reports

A Novel B7-2 (CD86) Splice Variant with a Putative Negative Regulatory Role

(2014) E. K. Kapsogeorgou et al.   JOURNAL OF IMMUNOLOGY

Molecular Requirements for MHC Class II  -Chain Engagement and Allelic Discrimination by the Bacterial Superantigen Streptococcal Pyrogenic Exotoxin C

(2014) K. J. Kasper et al.   JOURNAL OF IMMUNOLOGY

T Cell Receptor Signaling Can Directly Enhance the Avidity of CD28 Ligand Binding

(2014) Mariano Sanchez-Lockhart et al.   PLoS One

A Peptide Antagonist of CD28 Signaling Attenuates Toxic Shock and Necrotizing Soft-Tissue Infection Induced by Streptococcus pyogenes

(2013) Girish Ramachandran et al.   JOURNAL OF INFECTIOUS DISEASES

Binding of Superantigen Toxins into the CD28 Homodimer Interface Is Essential for Induction of Cytokine Genes That Mediate Lethal Shock

(2011) Gila Arad et al.   PLOS BIOLOGY