A Peptide Antagonist of CD28 Signaling Attenuates Toxic Shock and Necrotizing Soft-Tissue Infection Induced by Streptococcus pyogenes

New understandings in Streptococcus pyogenes

(2011) Nicola N Lynskey et al.   CURRENT OPINION IN INFECTIOUS DISEASES

Gram-positive bacterial superantigen outside-in signaling causes toxic shock syndrome

(2011) Amanda J. Brosnahan et al.   FEBS Journal

A Small Molecule That Mimics the BB-loop in the Toll Interleukin-1 (IL-1) Receptor Domain of MyD88 Attenuates Staphylococcal Enterotoxin B-induced Pro-inflammatory Cytokine Production and Toxicity in Mice

(2011) Teri L. Kissner et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Binding of Superantigen Toxins into the CD28 Homodimer Interface Is Essential for Induction of Cytokine Genes That Mediate Lethal Shock

(2011) Gila Arad et al.   PLOS BIOLOGY

A Single, Engineered Protein Therapeutic Agent Neutralizes Exotoxins from Both Staphylococcus aureus and Streptococcus pyogenes

(2010) N. Wang et al.   Clinical and Vaccine Immunology

Getting under the Skin: The Immunopathogenesis ofStreptococcus pyogenesDeep Tissue Infections

(2010) Linda Johansson et al.   CLINICAL INFECTIOUS DISEASES

Molecular Pathogenesis of Necrotizing Fasciitis

(2009) Randall J. Olsen et al.   Annual Review of Pathology-Mechanisms of Disease