Zinc Oxide Nanoparticles Induce Autophagy and Apoptosis via Oxidative Injury and Pro-Inflammatory Cytokines in Primary Astrocyte Cultures

Zinc oxide nanoparticle induced neurotoxic potential upon interaction with primary astrocytes

(2019) S. Sudhakaran et al.   NEUROTOXICOLOGY

Morphological and Biochemical Features of Cerebellar Cortex After Exposure to Zinc Oxide Nanoparticles: Possible Protective Role of Curcumin

(2018) Mona G. Amer et al.   Anatomical Record-Advances in Integrative Anatomy and Evolutionary Biology

Zinc oxide nanoparticles induce toxicity in CAL 27 oral cancer cell lines by activating PINK1/Parkin-mediated mitophagy

(2018) Jianfeng Wang et al.   International Journal of Nanomedicine

The Investigation of ZnO/Poly(vinylidene fluoride) Nanocomposites with Improved Mechanical, Piezoelectric, and Antimicrobial Properties for Orthopedic Applications

(2018) Yuan Li et al.   Journal of Biomedical Nanotechnology

Lipid-Coated Zinc Oxide Nanoparticles as Innovative ROS-Generators for Photodynamic Therapy in Cancer Cells

(2018) Andrea Ancona et al.   Nanomaterials

Autophagy in Age-Associated Neurodegeneration

(2018) Athanasios Metaxakis et al.   Cells

Health hazards of nanoparticles: understanding the toxicity mechanism of nanosized ZnO in cosmetic products

(2018) Vimala Devi Subramaniam et al.   DRUG AND CHEMICAL TOXICOLOGY

Synergistic Interaction Between Zinc and Reactive Oxygen Species Amplifies Ischemic Brain Injury in Rats

(2018) Yongmei Zhao et al.   STROKE

Influence of pristine and hydrophobic ZnO nanoparticles on cytotoxicity and endoplasmic reticulum (ER) stress-autophagy-apoptosis gene expression in A549-macrophage co-culture

(2018) Ting Liu et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Neuroinflammation is induced by tongue-instilled ZnO nanoparticles via the Ca2+-dependent NF-κB and MAPK pathways

(2018) Huimin Liang et al.   Particle and Fibre Toxicology

Zinc oxide nanoparticles induce apoptosis and autophagy in human ovarian cancer cells

(2017) Ding-Ping Bai et al.   International Journal of Nanomedicine

Piezoelectric nanotransducers: The future of neural stimulation

(2017) Attilio Marino et al.   Nano Today

Nanomaterial-induced cell death in pulmonary and hepatic cells following exposure to three different metallic materials: The role of autophagy and apoptosis

(2017) Ali Kermanizadeh et al.   Nanotoxicology

Rapamycin upregulates glutamate transporter and IL-6 expression in astrocytes in a mouse model of Parkinson’s disease

(2017) Yunlong Zhang et al.   Cell Death & Disease

Rapamycin Attenuates Acute Seizure-induced Astrocyte Injury in Mice in Vivo

(2017) Dongjun Guo et al.   Scientific Reports

Zinc Oxide Nanoparticle Induces Microglial Death by NADPH-Oxidase-Independent Reactive Oxygen Species as well as Energy Depletion

(2016) Anuj Kumar Sharma et al.   MOLECULAR NEUROBIOLOGY

Developmental Toxicity of Zinc Oxide Nanoparticles to Zebrafish (Danio rerio): A Transcriptomic Analysis

(2016) Jin Soo Choi et al.   PLoS One

Antibacterial, Structural and Optical Characterization of Mechano-Chemically Prepared ZnO Nanoparticles

(2016) Umair Manzoor et al.   PLoS One

Autophagy Mediates Astrocyte Death During Zinc-Potentiated Ischemia–Reperfusion Injury

(2015) Rong Pan et al.   BIOLOGICAL TRACE ELEMENT RESEARCH

Investigation on cellular interactions of astrocytes with zinc oxide nanoparticles using rat C6 cell lines

(2015) S. Sruthi et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Rapamycin increases neuronal survival, reduces inflammation and astrocyte proliferation after spinal cord injury

(2015) Yona Goldshmit et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Zinc oxide nanoparticles induce lipoxygenase-mediated apoptosis and necrosis in human neuroblastoma SH-SY5Y cells

(2015) Jun-Hyung Kim et al.   NEUROCHEMISTRY INTERNATIONAL

Neurotoxicity induced by zinc oxide nanoparticles: age-related differences and interaction

(2015) Lei Tian et al.   Scientific Reports

Zinc oxide nanoparticles affect the expression of p53, Ras p21 and JNKs: an ex vivo/in vitro exposure study in respiratory disease patients

(2014) Ashutosh Kumar et al.   MUTAGENESIS

Zinc oxide nanoparticles induce apoptosis by enhancement of autophagy via PI3K/Akt/mTOR inhibition

(2014) Ruchi Roy et al.   TOXICOLOGY LETTERS

ZnO nanoparticle-induced oxidative stress triggers apoptosis by activating JNK signaling pathway in cultured primary astrocytes

(2014) Jieting Wang et al.   Nanoscale Research Letters

Disruption of zinc homeostasis and the pathogenesis of senile dementia

(2013) Masahiro Kawahara et al.   Metallomics

Deferoxamine blocks death induced by glutathione depletion in PC 12 cells

(2013) E. Chouraqui et al.   NEUROTOXICOLOGY

Zinc oxide nanoparticle induced autophagic cell death and mitochondrial damage via reactive oxygen species generation

(2013) Kyeong-Nam Yu et al.   TOXICOLOGY IN VITRO

Mechanism of uptake of ZnO nanoparticles and inflammatory responses in macrophages require PI3K mediated MAPKs signaling

(2013) Ruchi Roy et al.   TOXICOLOGY IN VITRO

Demonstration of an Olfactory Bulb–Brain Translocation Pathway for ZnO Nanoparticles in Rodent Cells In Vitro and In Vivo

(2012) Yi-Yun Kao et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Potential neurotoxicity of nanoparticles

(2010) Yu-Lan Hu et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Zinc ion as modulator effects on excitability and synaptic transmission in hippocampal CA1 neurons in Wistar rats

(2010) Yutao Tian et al.   NEUROSCIENCE RESEARCH

Roles of zinc and metallothionein-3 in oxidative stress-induced lysosomal dysfunction, cell death, and autophagy in neurons and astrocytes

(2010) Sook-Jeong Lee et al.   Molecular Brain

Oxidative injury triggers autophagy in astrocytes: The role of endogenous zinc

(2009) Sook-Jeong Lee et al.   GLIA

Oxidative stress, calcium homeostasis, and altered gene expression in human lung epithelial cells exposed to ZnO nanoparticles

(2009) Chuan-Chin Huang et al.   TOXICOLOGY IN VITRO