Intracellular interleukin (IL)-1 family cytokine processing enzyme

Proinsulin Shares a Motif with Interleukin-1α (IL-1α) and Induces Inflammatory Cytokine via Interleukin-1 Receptor 1

(2016) Siyoung Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Neutrophil-Derived Proteases Escalate Inflammation through Activation of IL-36 Family Cytokines

(2016) Conor M. Henry et al.   Cell Reports

The interleukin (IL)-1 cytokine family – Balance between agonists and antagonists in inflammatory diseases

(2015) Jennifer Palomo et al.   CYTOKINE

T-bet– and STAT4–dependent IL-33 receptor expression directly promotes antiviral Th1 cell responses

(2015) Claudia Baumann et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Role of caspase-1 in nuclear translocation of IL-37, release of the cytokine, and IL-37 inhibition of innate immune responses

(2014) A.-M. Bulau et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Interleukin-37

(2013) Charles A. Dinarello et al.   SEMINARS IN IMMUNOLOGY

Contradictory Functions (Activation/Termination) of Neutrophil Proteinase 3 Enzyme (PR3) in Interleukin-33 Biological Activity

(2012) Suyoung Bae et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

IL-1 Family Members IL-18 and IL-33 Upregulate the Inflammatory Potential of Differentiated Human Th1 and Th2 Cultures

(2012) Lars Blom et al.   JOURNAL OF IMMUNOLOGY

Cutting Edge: FAS (CD95) Mediates Noncanonical IL-1  and IL-18 Maturation via Caspase-8 in an RIP3-Independent Manner

(2012) L. Bossaller et al.   JOURNAL OF IMMUNOLOGY

IL-38 binds to the IL-36 receptor and has biological effects on immune cells similar to IL-36 receptor antagonist

(2012) F. L. van de Veerdonk et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Interleukin-1 in the pathogenesis and treatment of inflammatory diseases

(2011) C. A. Dinarello   BLOOD

Interleukin-36 (IL-36) Ligands Require Processing for Full Agonist (IL-36α, IL-36β, and IL-36γ) or Antagonist (IL-36Ra) Activity

(2011) Jennifer E. Towne et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Identification of Constitutively Active Interleukin 33 (IL-33) Splice Variant

(2011) Jaewoo Hong et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Granzyme B-Dependent Proteolysis Acts as a Switch to Enhance the Proinflammatory Activity of IL-1α

(2011) Inna S. Afonina et al.   MOLECULAR CELL

Non-canonical inflammasome activation targets caspase-11

(2011) Nobuhiko Kayagaki et al.   NATURE

Epithelial-derived IL-33 and its receptor ST2 are dysregulated in ulcerative colitis and in experimental Th1/Th2 driven enteritis

(2010) Luca Pastorelli et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mature interleukin-33 is produced by calpain-mediated cleavage in vivo

(2009) Morisada Hayakawa et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Suppression of Interleukin-33 Bioactivity through Proteolysis by Apoptotic Caspases

(2009) Alexander U. Lüthi et al.   IMMUNITY

Interleukin-33 Is Biologically Active Independently of Caspase-1 Cleavage

(2009) Dominique Talabot-Ayer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Caspase-1, Caspase-8, and Calpain Are Dispensable for IL-33 Release by Macrophages

(2009) T. Ohno et al.   JOURNAL OF IMMUNOLOGY

IL-18 and IL-33 elicit Th2 cytokines from basophils via a MyD88- and p38α-dependent pathway

(2009) Kelly M. Kroeger et al.   JOURNAL OF LEUKOCYTE BIOLOGY

The IL-1-like cytokine IL-33 is inactivated after maturation by caspase-1

(2009) C. Cayrol et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IL-1, IL-18, and IL-33 families of cytokines

(2008) William P. Arend et al.   IMMUNOLOGICAL REVIEWS

IL-33 amplifies both Th1- and Th2-type responses through its activity on human basophils, allergen-reactive Th2 cells, iNKT and NK Cells

(2008) M. D. Smithgall et al.   INTERNATIONAL IMMUNOLOGY