Reaching the last mile: main challenges relating to and recommendations to accelerate onchocerciasis elimination in Africa

Onchocerciasis prevalence, human migration and risks for onchocerciasis elimination in the Upper Mouhoun, Nakambé and Nazinon river basins in Burkina Faso

(2018) Achille S. Nikièma et al.   ACTA TROPICA

How Can Onchocerciasis Elimination in Africa Be Accelerated? Modeling the Impact of Increased Ivermectin Treatment Frequency and Complementary Vector Control

(2018) Suzanne Verver et al.   CLINICAL INFECTIOUS DISEASES

A new powerful drug to combat river blindness

(2018) Michel Boussinesq   LANCET

Single dose moxidectin versus ivermectin for Onchocerca volvulus infection in Ghana, Liberia, and the Democratic Republic of the Congo: a randomised, controlled, double-blind phase 3 trial

(2018) Nicholas O Opoku et al.   LANCET

Neglected Tropical Diseases, Neglected Communities, and Conflict: How Do We Leave No One Behind?

(2018) Julie Jacobson et al.   TRENDS IN PARASITOLOGY

Innovative Surveillance Strategies to Support the Elimination of Filariasis in Africa

(2018) Louise A. Kelly-Hope et al.   TRENDS IN PARASITOLOGY

“Cross-border collaboration in onchocerciasis elimination in Uganda: progress, challenges and opportunities from 2008 to 2013”

(2018) Thomson Lakwo et al.   Globalization and Health

After 70 years of fighting an age-old scourge, onchocerciasis in Uganda, the end is in sight

(2018) Moses N Katabarwa et al.   International Health

Operationalization of the test and not treat strategy to accelerate the elimination of onchocerciasis and lymphatic filariasis in Central Africa

(2018) Joseph Kamgno et al.   International Health

Alternative treatment strategies to accelerate the elimination of onchocerciasis

(2018) Michel Boussinesq et al.   International Health

Transitioning from river blindness control to elimination: steps toward stopping treatment

(2018) Paul T Cantey et al.   International Health

Onchocerciasis: shifting the target from control to elimination requires a new first-step—elimination mapping

(2018) Maria P Rebollo et al.   International Health

Refocusing vector assessment towards the elimination of onchocerciasis from Africa: a review of the current status in selected countries

(2018) Daniel Boakye et al.   International Health

Onchocerciasis: the beginning of the end

(2018) Joni Lawrence et al.   International Health

Cross-border issues: an important component of onchocerciasis elimination programmes

(2018) Simon Bush et al.   International Health

For as Long as Necessary: Examining 30 years of MSD’s† Focus on Achieving Elimination of Onchocerciasis and Lymphatic Filariasis

(2018) Kenneth M Gustavsen et al.   International Health

Interruption of onchocerciasis transmission in Bioko Island: Accelerating the movement from control to elimination in Equatorial Guinea

(2018) Zaida Herrador et al.   PLoS Neglected Tropical Diseases

Onchocerca volvulus infection and serological prevalence, ocular onchocerciasis and parasite transmission in northern and central Togo after decades of Simulium damnosum s.l. vector control and mass drug administration of ivermectin

(2018) Kossi Komlan et al.   PLoS Neglected Tropical Diseases

Rethinking the serological threshold for onchocerciasis elimination

(2018) Katherine M. Gass   PLoS Neglected Tropical Diseases

From river blindness control to elimination: bridge over troubled water

(2018) Robert Colebunders et al.   Infectious Diseases of Poverty

Impact of five annual rounds of mass drug administration with ivermectin on onchocerciasis in Sierra Leone

(2018) Joseph B. Koroma et al.   Infectious Diseases of Poverty

Is onchocerciasis elimination in Africa feasible by 2025: a perspective based on lessons learnt from the African control programmes

(2018) Yankum Dadzie et al.   Infectious Diseases of Poverty

Factors affecting onchocerciasis transmission: lessons for infection control

(2017) Robert A. Cheke   Expert Review of Anti-Infective Therapy

Nodding syndrome: Preventable and treatable

(2017) Robert Colebunders et al.   Science Translational Medicine

Genome-wide analysis of ivermectin response by Onchocerca volvulus reveals that genetic drift and soft selective sweeps contribute to loss of drug sensitivity

(2017) Stephen R. Doyle et al.   PLoS Neglected Tropical Diseases

Onchocerciasis in the Democratic Republic of Congo: Survey of knowledge, attitude and perception in Bandundu province

(2017) Jean-Claude Makenga Bof et al.   Journal of Infection and Public Health

The First Confirmed Elimination of an Onchocerciasis Focus in Africa: Abu Hamed, Sudan

(2016) Isam M. A. Zarroug et al.   AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE

Still mesoendemic onchocerciasis in two Cameroonian community-directed treatment with ivermectin projects despite more than 15 years of mass treatment

(2016) Guy-Roger Kamga et al.   Parasites & Vectors

Cross-border collaboration for neglected tropical disease efforts—Lessons learned from onchocerciasis control and elimination in the Mano River Union (West Africa)

(2016) Kenneth Gustavsen et al.   Globalization and Health

Neglected tropical diseases in Africa: a new paradigm

(2016) Adrian D. Hopkins   International Health

A Recombinant Positive Control for Serology Diagnostic Tests Supporting Elimination of Onchocerca volvulus

(2016) Allison Golden et al.   PLoS Neglected Tropical Diseases

Model-Based Geostatistical Mapping of the Prevalence of Onchocerca volvulus in West Africa

(2016) Simon J. O’Hanlon et al.   PLoS Neglected Tropical Diseases

Factors Associated with Ivermectin Non-Compliance and Its Potential Role in Sustaining Onchocerca volvulus Transmission in the West Region of Cameroon

(2016) Laura Senyonjo et al.   PLoS Neglected Tropical Diseases

Research for new drugs for elimination of onchocerciasis in Africa

(2016) Annette C. Kuesel   International Journal for Parasitology-Drugs and Drug Resistance

Progress towards onchocerciasis elimination in the participating countries of the African Programme for Onchocerciasis Control: epidemiological evaluation results

(2016) Afework H. Tekle et al.   Infectious Diseases of Poverty

Rapid Point-of-Contact Tool for Mapping and Integrated Surveillance of Wuchereria bancrofti and Onchocerca volvulus Infection

(2015) Cathy Steel et al.   Clinical and Vaccine Immunology

Predictors of compliance with community-directed treatment with ivermectin for onchocerciasis control in Kabo area, southwestern Ethiopia

(2015) Adugna Endale et al.   Parasites & Vectors

The potential impact of moxidectin on onchocerciasis elimination in Africa: an economic evaluation based on the Phase II clinical trial data

(2015) Hugo C Turner et al.   Parasites & Vectors

Relationship between oral declaration on adherence to ivermectin treatment and parasitological indicators of onchocerciasis in an area of persistent transmission despite a decade of mass drug administration in Cameroon

(2015) Samuel Wanji et al.   Parasites & Vectors

Onchocerciasis Transmission in Ghana: Persistence under Different Control Strategies and the Role of the Simuliid Vectors

(2015) Poppy H. L. Lamberton et al.   PLoS Neglected Tropical Diseases

Control, Elimination, and Eradication of River Blindness: Scenarios, Timelines, and Ivermectin Treatment Needs in Africa

(2015) Young Eun Kim et al.   PLoS Neglected Tropical Diseases

Managing the Fight against Onchocerciasis in Africa: APOC Experience

(2015) Grace Fobi et al.   PLoS Neglected Tropical Diseases

40 Years of the APOC Partnership

(2015) Jean-Baptist Roungou et al.   PLoS Neglected Tropical Diseases

Growth, Challenges, and Solutions over 25 Years of Mectizan and the Impact on Onchocerciasis Control

(2015) Joni Lawrence et al.   PLoS Neglected Tropical Diseases

Hypo-endemic onchocerciasis hotspots: defining areas of high risk through micro-mapping and environmental delineation

(2015) Louise A. Kelly-Hope et al.   Infectious Diseases of Poverty

Reaching the London Declaration on Neglected Tropical Diseases Goals for Onchocerciasis: An Economic Evaluation of Increasing the Frequency of Ivermectin Treatment in Africa

(2014) Hugo C. Turner et al.   CLINICAL INFECTIOUS DISEASES

Therapeutic Efficacy and Macrofilaricidal Activity of Doxycycline for the Treatment of River Blindness

(2014) Martin Walker et al.   CLINICAL INFECTIOUS DISEASES

Modelling the impact of ivermectin on River Blindness and its burden of morbidity and mortality in African Savannah: EpiOncho projections

(2014) Hugo C Turner et al.   Parasites & Vectors

The geographic distribution of onchocerciasis in the 20 participating countries of the African Programme for Onchocerciasis Control: (1) priority areas for ivermectin treatment

(2014) Mounkaila Noma et al.   Parasites & Vectors

The geographic distribution of onchocerciasis in the 20 participating countries of the African Programme for Onchocerciasis Control: (2) pre-control endemicity levels and estimated number infected

(2014) Honorat GM Zouré et al.   Parasites & Vectors

Elimination of African Onchocerciasis: Modeling the Impact of Increasing the Frequency of Ivermectin Mass Treatment

(2014) Luc E. Coffeng et al.   PLoS One

Onchocerciasis control in the Democratic Republic of Congo (DRC): challenges in a post-war environment

(2014) J.-C. Makenga Bof et al.   TROPICAL MEDICINE & INTERNATIONAL HEALTH

African Programme for Onchocerciasis Control 1995–2015: Updated Health Impact Estimates Based on New Disability Weights

(2014) Luc E. Coffeng et al.   PLoS Neglected Tropical Diseases

Status of Onchocerciasis Transmission after More Than a Decade of Mass Drug Administration for Onchocerciasis and Lymphatic Filariasis Elimination in Central Nigeria: Challenges in Coordinating the Stop MDA Decision

(2014) Darin S. Evans et al.   PLoS Neglected Tropical Diseases

Reproductive Status of Onchocerca volvulus after Ivermectin Treatment in an Ivermectin-Naïve and a Frequently Treated Population from Cameroon

(2014) Hugues C. Nana-Djeunga et al.   PLoS Neglected Tropical Diseases

A Randomized, Single-Ascending-Dose, Ivermectin-Controlled, Double-Blind Study of Moxidectin in Onchocerca volvulus Infection

(2014) Kwablah Awadzi et al.   PLoS Neglected Tropical Diseases

The disappearance of onchocerciasis from the Itwara focus, western Uganda after elimination of the vector Simulium neavei and 19 years of annual ivermectin treatments

(2013) T.L. Lakwo et al.   ACTA TROPICA

Measuring Treatment Coverage for Neglected Tropical Disease Control Programs: Analysis of a Survey Design

(2013) M. C. Baker et al.   AMERICAN JOURNAL OF EPIDEMIOLOGY

Preventive chemotherapy as a strategy for elimination of neglected tropical parasitic diseases: endgame challenges

(2013) M. J. Bockarie et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Dynamics of Onchocerca volvulus Microfilarial Densities after Ivermectin Treatment in an Ivermectin-naïve and a Multiply Treated Population from Cameroon

(2013) Sébastien D. S. Pion et al.   PLoS Neglected Tropical Diseases

African Programme for Onchocerciasis Control 1995–2015: Model-Estimated Health Impact and Cost

(2013) Luc E. Coffeng et al.   PLoS Neglected Tropical Diseases

Onchocerciasis: The Pre-control Association between Prevalence of Palpable Nodules and Skin Microfilariae

(2013) Luc E. Coffeng et al.   PLoS Neglected Tropical Diseases

Case-control Studies on the Relationship between Onchocerciasis and Epilepsy: Systematic Review and Meta-analysis

(2013) Christoph Kaiser et al.   PLoS Neglected Tropical Diseases

History of Avermectin and Ivermectin, with Notes on the History of Other Macrocyclic Lactone Antiparasitic Agents

(2012) William C. Campbell   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

Single nucleotide polymorphisms in β-tubulin selected in Onchocerca volvulus following repeated ivermectin treatment: Possible indication of resistance selection

(2012) Hugues Nana-Djeunga et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

Impact of long-term treatment of onchocerciasis with ivermectin in Kaduna State, Nigeria: first evidence of the potential for elimination in the operational area of the African Programme for Onchocerciasis Control

(2012) Afework Tekle et al.   Parasites & Vectors

Why do community health workers volunteer? A qualitative study in Kenya

(2012) T. Takasugi et al.   PUBLIC HEALTH

The onchocerciasis chronicle: from the beginning to the end?

(2012) Andy Crump et al.   TRENDS IN PARASITOLOGY

Implementing Preventive Chemotherapy through an Integrated National Neglected Tropical Disease Control Program in Mali

(2012) Massitan Dembélé et al.   PLoS Neglected Tropical Diseases

Proof-of-Principle of Onchocerciasis Elimination with Ivermectin Treatment in Endemic Foci in Africa: Final Results of a Study in Mali and Senegal

(2012) Mamadou O. Traore et al.   PLoS Neglected Tropical Diseases

Genotypic analysis of β-tubulin in Onchocerca volvulus from communities and individuals showing poor parasitological response to ivermectin treatment

(2012) Mike Y. Osei-Atweneboana et al.   International Journal for Parasitology-Drugs and Drug Resistance

Filariasis in Africa—treatment challenges and prospects

(2011) A. Hoerauf et al.   CLINICAL MICROBIOLOGY AND INFECTION

Compliance with eight years of annual ivermectin treatment of onchocerciasis in Cameroon and Nigeria

(2011) William R Brieger et al.   Parasites & Vectors

Elimination of onchocerciasis from Africa: possible?

(2011) Charles D. Mackenzie et al.   TRENDS IN PARASITOLOGY

The African Programme for Onchocerciasis Control: impact on onchocercal skin disease

(2011) G. A. Ozoh et al.   TROPICAL MEDICINE & INTERNATIONAL HEALTH

Where would I be without ivermectin? Capturing the benefits of community-directed treatment with ivermectin in Africa

(2011) Joseph C. Okeibunor et al.   TROPICAL MEDICINE & INTERNATIONAL HEALTH

Phenotypic Evidence of Emerging Ivermectin Resistance in Onchocerca volvulus

(2011) Mike Y. Osei-Atweneboana et al.   PLoS Neglected Tropical Diseases

The Geographic Distribution of Loa loa in Africa: Results of Large-Scale Implementation of the Rapid Assessment Procedure for Loiasis (RAPLOA)

(2011) Honorat Gustave Marie Zouré et al.   PLoS Neglected Tropical Diseases

Mectizan® procurement and delivery for onchocerciasis mass drug administration programmes

(2010) Kisito T. Ogoussan et al.   ACTA TROPICA

Elimination of human onchocerciasis: History of progress and current feasibility using ivermectin (Mectizan®) monotherapy

(2010) E.W. Cupp et al.   ACTA TROPICA

Genetic polymorphisms in MDR1, CYP3A4 and CYP3A5 genes in a Ghanaian population: a plausible explanation for altered metabolism of ivermectin in humans?

(2010) William Kudzi et al.   BMC Medical Genetics

Factors associated with compliance with community directed treatment with ivermectin for onchocerciasis control in Southwestern Ethiopia

(2010) Daniel Yirga et al.   Parasites & Vectors

Does onchocerciasis transmission take place in hypoendemic areas? a study from the North Region of Cameroon

(2010) Moses N. Katabarwa et al.   TROPICAL MEDICINE & INTERNATIONAL HEALTH

How to (or Not to) Integrate Vertical Programmes for the Control of Major Neglected Tropical Diseases in Sub-Saharan Africa

(2010) Narcis B. Kabatereine et al.   PLoS Neglected Tropical Diseases

Challenges for the integration of mass drug administrations against multiple 'neglected tropical diseases'

(2009) A. D. Hopkins   ANNALS OF TROPICAL MEDICINE AND PARASITOLOGY

Sustainability of ivermectin distribution programmes

(2009) Lindsay J Rakers et al.   LANCET

Identifying sub-optimal responses to ivermectin in the treatment of River Blindness

(2009) T. S. Churcher et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Perceptions on onchocerciasis and ivermectin treatment in rural communities in Uganda: implications for long-term compliance

(2009) Richard Ndyomugyenyi et al.   International Health

Feasibility of Onchocerciasis Elimination with Ivermectin Treatment in Endemic Foci in Africa: First Evidence from Studies in Mali and Senegal

(2009) Lamine Diawara et al.   PLoS Neglected Tropical Diseases

Neglected Tropical Diseases in Sub-Saharan Africa: Review of Their Prevalence, Distribution, and Disease Burden

(2009) Peter J. Hotez et al.   PLoS Neglected Tropical Diseases

The African Programme for Onchocerciasis Control (APOC)

(2008) U. Amazigo   ANNALS OF TROPICAL MEDICINE AND PARASITOLOGY

The Onchocerciasis Control Programme in West Africa (OCP)

(2008) B. Boatin   ANNALS OF TROPICAL MEDICINE AND PARASITOLOGY