Repair Process Impairment by Pseudomonas aeruginosa in Epithelial Tissues: Major Features and Potential Therapeutic Avenues

Lifestyle transitions and adaptive pathogenesis of Pseudomonas aeruginosa

(2018) Martina Valentini et al.   CURRENT OPINION IN MICROBIOLOGY

Antimicrobial blue light photoinactivation of Pseudomonas aeruginosa : Quorum sensing signaling molecules, biofilm formation and pathogenicity

(2018) Fila Grzegorz et al.   Journal of Biophotonics

Longitudinal development of initial, chronic and mucoid Pseudomonas aeruginosa infection in young children with cystic fibrosis

(2018) S.L. Heltshe et al.   Journal of Cystic Fibrosis

CFTR rescue with VX-809 and VX-770 favors the repair of primary airway epithelial cell cultures from patients with class II mutations in the presence of Pseudomonas aeruginosa exoproducts

(2018) Damien Adam et al.   Journal of Cystic Fibrosis

Enhanced sterilization and healing of cutaneous pseudomonas infection using 5-aminolevulinic acid as a photosensitizer with 410-nm LED light

(2018) Bunpei Katayama et al.   JOURNAL OF DERMATOLOGICAL SCIENCE

Discovery, research, and development of new antibiotics: the WHO priority list of antibiotic-resistant bacteria and tuberculosis

(2018) Evelina Tacconelli et al.   LANCET INFECTIOUS DISEASES

Interaction between Staphylococcus aureus and Pseudomonas aeruginosa is beneficial for colonisation and pathogenicity in a mixed biofilm

(2018) Patrícia M Alves et al.   Pathogens and Disease

Antimicrobial Peptides and Their Therapeutic Potential for Bacterial Skin Infections and Wounds

(2018) Anja Pfalzgraff et al.   Frontiers in Pharmacology

Co-occurrence of Anaerobes in Human Chronic Wounds

(2018) Yongwook Choi et al.   MICROBIAL ECOLOGY

Pseudomonas aeruginosa flagellum is critical for invasion, cutaneous persistence and induction of inflammatory response of skin epidermis

(2018) Magali Garcia et al.   Virulence

A novel murine model for contact lens wear reveals clandestine IL-1R dependent corneal parainflammation and susceptibility to microbial keratitis upon inoculation with Pseudomonas aeruginosa

(2018) Matteo M.E. Metruccio et al.   Ocular Surface

Higher Prevalence of PldA, a Pseudomonas aeruginosa Trans-Kingdom H2-Type VI Secretion System Effector, in Clinical Isolates Responsible for Acute Infections and in Multidrug Resistant Strains

(2018) Thibaud Boulant et al.   Frontiers in Microbiology

Apitherapeutics and phage-loaded nanofibers as wound dressings with enhanced wound healing and antibacterial activity

(2017) Wessam A Sarhan et al.   Nanomedicine

Phage therapy is highly effective against chronic lung infections with Pseudomonas aeruginosa

(2017) Elaine M Waters et al.   THORAX

Pseudomonas aeruginosaLasB protease impairs innate immunity in mice and humans by targeting a lung epithelial cystic fibrosis transmembrane regulator–IL-6–antimicrobial–repair pathway

(2017) Vinciane Saint-Criq et al.   THORAX

Histopathological comparisons of S taphylococcus aureus and P seudomonas aeruginosa experimental infected porcine burn wounds

(2017) Sarah B. Chaney et al.   WOUND REPAIR AND REGENERATION

In vivo therapeutic efficacy of frog skin-derived peptides against Pseudomonas aeruginosa-induced pulmonary infection

(2017) Chen Chen et al.   Scientific Reports

Aggressive necrotizing pseudomonal sinonasal infections

(2017) Edward C. Kuan et al.   International Forum of Allergy & Rhinology

Quorum Sensing Down-Regulation Counteracts the Negative Impact of Pseudomonas aeruginosa on CFTR Channel Expression, Function and Rescue in Human Airway Epithelial Cells

(2017) Émilie Maillé et al.   Frontiers in Cellular and Infection Microbiology

Porcine Models of Biofilm Infections with Focus on Pathomorphology

(2017) Louise K. Jensen et al.   Frontiers in Microbiology

Komodo dragon-inspired synthetic peptide DRGN-1 promotes wound-healing of a mixed-biofilm infected wound

(2017) Ezra M.C. Chung et al.   npj Biofilms and Microbiomes

Lipoxin A4 encapsulated in PLGA microparticles accelerates wound healing of skin ulcers

(2017) Mouzarllem Barros Reis et al.   PLoS One

Lipoxin A4 prevents tight junction disruption and delays the colonization of cystic fibrosis bronchial epithelial cells by Pseudomonas aeruginosa

(2016) Gerard Higgins et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Pseudomonas aeruginosa lectin LecB inhibits tissue repair processes by triggering β-catenin degradation

(2016) Catherine Cott et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Quorum-sensing inhibition abrogates the deleterious impact of Pseudomonas aeruginosa on airway epithelial repair

(2016) Manon Ruffin et al.   FASEB JOURNAL

Inhibition of endotoxin-induced airway epithelial cell injury by a novel family of pyrrol derivates

(2016) Nuria E Cabrera-Benítez et al.   LABORATORY INVESTIGATION

RNA-Seq Transcriptomic Responses of Full-Thickness Dermal Excision Wounds to Pseudomonas aeruginosa Acute and Biofilm Infection

(2016) S. L. Rajasekhar Karna et al.   PLoS One

Chemotaxis and Binding of Pseudomonas aeruginosa to Scratch-Wounded Human Cystic Fibrosis Airway Epithelial Cells

(2016) Christian Schwarzer et al.   PLoS One

Pseudomonas aeruginosa Transmigrates at Epithelial Cell-Cell Junctions, Exploiting Sites of Cell Division and Senescent Cell Extrusion

(2016) Guillaume Golovkine et al.   PLoS Pathogens

Management of traumatic wounds in the Emergency Department: position paper from the Academy of Emergency Medicine and Care (AcEMC) and the World Society of Emergency Surgery (WSES)

(2016) Carolina Prevaldi et al.   World Journal of Emergency Surgery

Tracking the immunopathological response to Pseudomonas aeruginosa during respiratory infections

(2016) Cristina Cigana et al.   Scientific Reports

Synthetic antimicrobial and LPS-neutralising peptides suppress inflammatory and immune responses in skin cells and promote keratinocyte migration

(2016) Anja Pfalzgraff et al.   Scientific Reports

Airway Epithelial Cell Integrity Protects from Cytotoxicity ofPseudomonas aeruginosaQuorum-Sensing Signals

(2015) Davide Losa et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Overcoming barriers in Pseudomonas aeruginosa lung infections: Engineered nanoparticles for local delivery of a cationic antimicrobial peptide

(2015) Ivana d’Angelo et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Cross-regulation of Pseudomonas motility systems: the intimate relationship between flagella, pili and virulence

(2015) Barbara I Kazmierczak et al.   CURRENT OPINION IN MICROBIOLOGY

Deleterious impact ofPseudomonas aeruginosaon cystic fibrosis transmembrane conductance regulator function and rescue in airway epithelial cells

(2015) Nguyen Thu Ngan Trinh et al.   EUROPEAN RESPIRATORY JOURNAL

Chronic wound infections: the role ofPseudomonas aeruginosaandStaphylococcus aureus

(2015) Raffaele Serra et al.   Expert Review of Anti-Infective Therapy

Dynamically Regulated CFTR Expression and Its Functional Role in Cutaneous Wound Healing

(2015) Jianda Dong et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Microbiology and outcomes of community acquired pneumonia in non cystic-fibrosis bronchiectasis patients

(2015) Eva Polverino et al.   JOURNAL OF INFECTION

Pseudomonas aeruginosauses T3SS to inhibit diabetic wound healing

(2015) Josef Goldufsky et al.   WOUND REPAIR AND REGENERATION

Inhibition ofPseudomonas aeruginosabiofilm formation on wound dressings

(2015) Kenneth S. Brandenburg et al.   WOUND REPAIR AND REGENERATION

Pseudomonas Exotoxin A: optimized by evolution for effective killing

(2015) Marta Michalska et al.   Frontiers in Microbiology

Pseudomonas aeruginosa Reduces VX-809 Stimulated F508del-CFTR Chloride Secretion by Airway Epithelial Cells

(2015) Bruce A. Stanton et al.   PLoS One

Secreted biofilm factors adversely affect cellular wound healing responses in vitro

(2015) Robert Jeffery Marano et al.   Scientific Reports

Putting on the brakes: Bacterial impediment of wound healing

(2015) Kimberly M. Brothers et al.   Scientific Reports

Mast Cells Protect against Pseudomonas aeruginosa–Induced Lung Injury

(2014) Robert D. Junkins et al.   AMERICAN JOURNAL OF PATHOLOGY

Interclonal gradient of virulence in thePseudomonas aeruginosapangenome from disease and environment

(2014) Rolf Hilker et al.   ENVIRONMENTAL MICROBIOLOGY

A multifunctional peptide based on the neutrophil immune defense molecule, CAP37, has antibacterial and wound-healing properties

(2014) Anne Kasus-Jacobi et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Mixed-species biofilm compromises wound healing by disrupting epidermal barrier function

(2014) Sashwati Roy et al.   JOURNAL OF PATHOLOGY

Requirements for Pseudomonas aeruginosa Acute Burn and Chronic Surgical Wound Infection

(2014) Keith H. Turner et al.   PLoS Genetics

The hierarchy quorum sensing network in Pseudomonas aeruginosa

(2014) Jasmine Lee et al.   Protein & Cell

Imipenem, Meropenem, or Doripenem To Treat Patients with Pseudomonas aeruginosa Ventilator-Associated Pneumonia

(2013) Charles-Edouard Luyt et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Structure and Function of the Type III Secretion System of Pseudomonas aeruginosa

(2013) Marlies Galle et al.   CURRENT PROTEIN & PEPTIDE SCIENCE

Neutrophil-derived tumor necrosis factor-α contributes to acute wound healing promoted by N-(3-oxododecanoyl)-l-homoserine lactone from Pseudomonas aeruginosa

(2013) Emi Kanno et al.   JOURNAL OF DERMATOLOGICAL SCIENCE

Porphyromonas gingivalis modulates Pseudomonas aeruginosa-induced apoptosis of respiratory epithelial cells through the STAT3 signaling pathway

(2013) Qian Li et al.   MICROBES AND INFECTION

Interactions of Methicillin Resistant Staphylococcus aureus USA300 and Pseudomonas aeruginosa in Polymicrobial Wound Infection

(2013) Irena Pastar et al.   PLoS One

MicroRNA-762 Is Upregulated in Human Corneal Epithelial Cells in Response to Tear Fluid and Pseudomonas aeruginosa Antigens and Negatively Regulates the Expression of Host Defense Genes Encoding RNase7 and ST2

(2013) James Mun et al.   PLoS One

Wound healing potential of topical bacteriophage therapy on diabetic cutaneous wounds

(2013) João J. Mendes et al.   WOUND REPAIR AND REGENERATION

Pseudomonas aeruginosa: new insights into pathogenesis and host defenses

(2013) Shaan L. Gellatly et al.   Pathogens and Disease

The Pseudomonas aeruginosa quorum sensing signal molecule N-(3-oxododecanoyl) homoserine lactone enhances keratinocyte migration and induces Mmp13 gene expression in vitro

(2012) Camila Paes et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Quorum sensing inhibitors: An overview

(2012) Vipin Chandra Kalia   BIOTECHNOLOGY ADVANCES

Improvement of defective cystic fibrosis airway epithelial wound repair after CFTR rescue

(2012) Nguyen Thu Ngan Trinh et al.   EUROPEAN RESPIRATORY JOURNAL

Lipoxin A4 inhibits platelet-activating factor inflammatory response and stimulates corneal wound healing of injuries that compromise the stroma

(2012) Azucena Kakazu et al.   EXPERIMENTAL EYE RESEARCH

Pseudomonas aeruginosa Keratitis in Mice: Effects of Topical Bacteriophage KPP12 Administration

(2012) Ken Fukuda et al.   PLoS One

Impact of Pseudomonas aeruginosa quorum sensing on cellular wound healing responses in vitro

(2012) Jasper N. Jacobsen et al.   SCANDINAVIAN JOURNAL OF INFECTIOUS DISEASES

Bacteriophages  MR299-2 and  NH-4 Can Eliminate Pseudomonas aeruginosa in the Murine Lung and on Cystic Fibrosis Lung Airway Cells

(2012) D. Alemayehu et al.   mBio

Pneumonia Due to Pseudomonas aeruginosa

(2011) Shigeki Fujitani et al.   CHEST

ThePseudomonas aeruginosaquorum-sensing signalN-(3-oxododecanoyl) homoserine lactone can accelerate cutaneous wound healing through myofibroblast differentiation in rats

(2011) Gojiro Nakagami et al.   FEMS IMMUNOLOGY AND MEDICAL MICROBIOLOGY

An overview of international literature from cystic fibrosis registries. Part 3. Disease incidence, genotype/phenotype correlation, microbiology, pregnancy, clinical complications, lung transplantation, and miscellanea

(2011) Donatello Salvatore et al.   Journal of Cystic Fibrosis

Drug and light delivery strategies for photodynamic antimicrobial chemotherapy (PACT) of pulmonary pathogens: A pilot study

(2011) Corona M. Cassidy et al.   Photodiagnosis and Photodynamic Therapy

The Human Airway Epithelial Basal Cell Transcriptome

(2011) Neil R. Hackett et al.   PLoS One

Susceptibility of Pseudomonas aeruginosa Biofilm to Alpha-Helical Peptides: D-enantiomer of LL-37

(2011) Scott N. Dean et al.   Frontiers in Microbiology

Cystic fibrosis transmembrane conductance regulator is involved in airway epithelial wound repair

(2010) Katherine R. Schiller et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Infection of human mucosal tissue by Pseudomonas aeruginosa requires sequential and mutually dependent virulence factors and a novel pilus-associated adhesin

(2010) Ryan W. Heiniger et al.   CELLULAR MICROBIOLOGY

Chloride channels and transporters in human corneal epithelium

(2010) Lin Cao et al.   EXPERIMENTAL EYE RESEARCH

TLR4 and TLR5 on Corneal Macrophages Regulate Pseudomonas aeruginosa Keratitis by Signaling through MyD88-Dependent and -Independent Pathways

(2010) Y. Sun et al.   JOURNAL OF IMMUNOLOGY

Flagellin-Induced Corneal Antimicrobial Peptide Production and Wound Repair Involve a Novel NF-κB–Independent and EGFR-Dependent Pathway

(2010) Nan Gao et al.   PLoS One

Mucoidy, Quorum Sensing, Mismatch Repair and Antibiotic Resistance in Pseudomonas aeruginosa from Cystic Fibrosis Chronic Airways Infections

(2010) Sofía Feliziani et al.   PLoS One

Delayed wound healing in diabetic (db/db) mice with Pseudomonas aeruginosa biofilm challenge: a model for the study of chronic wounds

(2010) Ge Zhao et al.   WOUND REPAIR AND REGENERATION

Inhibition of Macrophage Migration Inhibitory Factor Ameliorates Ocular Pseudomonas aeruginosa-Induced Keratitis

(2010) Mihaela Gadjeva et al.   PLoS Pathogens

Pseudomonas aeruginosa Exotoxin Pyocyanin Causes Cystic Fibrosis Airway Pathogenesis

(2009) Charles C. Caldwell et al.   AMERICAN JOURNAL OF PATHOLOGY

Pseudomonas pyocyanin inhibits wound repair by inducing premature cellular senescence: Role for p38 mitogen-activated protein kinase

(2009) Michael Muller et al.   BURNS

The Role of Scgb1a1+ Clara Cells in the Long-Term Maintenance and Repair of Lung Airway, but Not Alveolar, Epithelium

(2009) Emma L. Rawlins et al.   Cell Stem Cell

Risk Factors and Causative Organisms in Microbial Keratitis

(2009) Matthew Green et al.   CORNEA

Role of Pseudomonas aeruginosa type III effectors in disease

(2009) Joanne Engel et al.   CURRENT OPINION IN MICROBIOLOGY

Pseudomonas aeruginosa in adults with chronic obstructive pulmonary disease

(2009) Timothy F Murphy   CURRENT OPINION IN PULMONARY MEDICINE

Clinical review of corneal ulcers resulting in evisceration and enucleation in elderly population

(2009) Marios Constantinou et al.   GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY

Role of LecA and LecB Lectins in Pseudomonas aeruginosa-Induced Lung Injury and Effect of Carbohydrate Ligands

(2009) C. Chemani et al.   INFECTION AND IMMUNITY

Engraftment of Bone Marrow–derived Stem Cells to the Lung in a Model of Acute Respiratory Infection by Pseudomonas aeruginosa

(2009) Joanna Rejman et al.   MOLECULAR THERAPY

The type III secretion system of Pseudomonas aeruginosa: infection by injection

(2009) Alan R. Hauser   NATURE REVIEWS MICROBIOLOGY

Development of Three-Dimensional Tissue-Engineered Models of Bacterial Infected Human Skin Wounds

(2009) Joanna Shepherd et al.   TISSUE ENGINEERING PART C-METHODS

Ciliated epithelial cell lifespan in the mouse trachea and lung

(2008) Emma L. Rawlins et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

The Pseudomonas aeruginosa type III secreted toxin ExoT is necessary and sufficient to induce apoptosis in epithelial cells

(2008) Sasha H. Shafikhani et al.   CELLULAR MICROBIOLOGY

ChronicPseudomonas aeruginosaInfection in Chronic Obstructive Pulmonary Disease

(2008) Laura Martínez‐Solano et al.   CLINICAL INFECTIOUS DISEASES

Distribution, Organization, and Ecology of Bacteria in Chronic Wounds

(2008) K. Kirketerp-Moller et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Ventilator-associated pneumonia caused by multidrug-resistant organisms or Pseudomonas aeruginosa: Prevalence, incidence, risk factors, and outcomes

(2008) Chris M. Parker et al.   JOURNAL OF CRITICAL CARE

The potential of desferrioxamine-gallium as an anti-Pseudomonas therapeutic agent

(2008) E. Banin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inhibition of keratinocyte migration by lipopolysaccharide

(2007) Chris Loryman et al.   WOUND REPAIR AND REGENERATION