Replication Study: Wnt activity defines colon cancer stem cells and is regulated by the microenvironment

Identification, isolation and characterization of human LGR5-positive colon adenoma cells

(2018) Michael K. Dame et al.   DEVELOPMENT

Morphological alterations of cultured human colorectal matched tumour and healthy organoids

(2018) Seyed Mohammad Hossein Kashfi et al.   Oncotarget

An improved method for culturing patient-derived colorectal cancer spheroids

(2018) Hiroyuki Miyoshi et al.   Oncotarget

Genetic and transcriptional evolution alters cancer cell line drug response

(2018) Uri Ben-David et al.   NATURE

Microenvironmental cues in cancer stemness

(2018) D. J. Flanagan et al.   NATURE CELL BIOLOGY

Stem cell functionality is microenvironmentally defined during tumour expansion and therapy response in colon cancer

(2018) Kristiaan J. Lenos et al.   NATURE CELL BIOLOGY

Multifaceted Interpretation of Colon Cancer Stem Cells

(2017) Yuichiro Hatano et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Visualization and targeting of LGR5+ human colon cancer stem cells

(2017) Mariko Shimokawa et al.   NATURE

A Colorectal Tumor Organoid Library Demonstrates Progressive Loss of Niche Factor Requirements during Tumorigenesis

(2016) Masayuki Fujii et al.   Cell Stem Cell

Adapting Cancer Immunotherapy Models for the Real World

(2016) Lauryn E. Klevorn et al.   TRENDS IN IMMUNOLOGY

LIG4 mediates Wnt signalling-induced radioresistance

(2016) Sohee Jun et al.   Nature Communications

Genetic variability in a frozen batch of MCF-7 cells invisible in routine authentication affecting cell function

(2016) Andre Kleensang et al.   Scientific Reports

What Do We Learn from Spheroid Culture Systems? Insights from Tumorspheres Derived from Primary Colon Cancer Tissue

(2016) Komal Qureshi-Baig et al.   PLoS One

Targeting LGR5 + cells with an antibody-drug conjugate for the treatment of colon cancer

(2015) Melissa R. Junttila et al.   Science Translational Medicine

Humanized anti-hepatocyte growth factor (HGF) antibody suppresses innate irinotecan (CPT-11) resistance induced by fibroblast-derived HGF

(2015) Jong Kyu Woo et al.   Oncotarget

Registered report: Wnt activity defines colon cancer stem cells and is regulated by the microenvironment

(2015) James Evans et al.   eLife

An aberrant nuclear localization of E-cadherin is a potent inhibitor of Wnt/β-catenin-elicited promotion of the cancer stem cell phenotype

(2015) Y-J Su et al.   Oncogenesis

Conducting Meta-Analyses inRwith themetaforPackage

(2015) Wolfgang Viechtbauer   Journal of Statistical Software

Prognostic significance of CD44 variant 2 upregulation in colorectal cancer

(2014) M Ozawa et al.   BRITISH JOURNAL OF CANCER

Refinement of Experimental Design and Conduct in Laboratory Animal Research

(2014) J. D. Bailoo et al.   ILAR JOURNAL

Animal Husbandry and Experimental Design

(2014) T. Nevalainen   ILAR JOURNAL

Standardised animal models of host microbial mutualism

(2014) A J Macpherson et al.   Mucosal Immunology

Olfactory exposure to males, including men, causes stress and related analgesia in rodents

(2014) Robert E Sorge et al.   NATURE METHODS

An open investigation of the reproducibility of cancer biology research

(2014) Timothy M Errington et al.   eLife

Baseline tumor growth and immune control in laboratory mice are significantly influenced by subthermoneutral housing temperature

(2013) K. M. Kokolus et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

FlowRepository: A resource of annotated flow cytometry datasets associated with peer-reviewed publications

(2012) Josef Spidlen et al.   CYTOMETRY PART A

CD133+, CD166+CD44+, and CD24+CD44+ Phenotypes Fail to Reliably Identify Cell Populations with Cancer Stem Cell Functional Features in Established Human Colorectal Cancer Cell Lines

(2012) Manuele Giuseppe Muraro et al.   Stem Cells Translational Medicine

Highly enriched CD133+CD44+ stem-like cells with CD133+CD44high metastatic subset in HCT116 colon cancer cells

(2011) Ke-li Chen et al.   CLINICAL & EXPERIMENTAL METASTASIS

Inbred mouse strains and genetic stability: a review

(2010) J. Casellas   Animal

Wnt activity defines colon cancer stem cells and is regulated by the microenvironment

(2010) Louis Vermeulen et al.   NATURE CELL BIOLOGY

Tackling the widespread and critical impact of batch effects in high-throughput data

(2010) Jeffrey T. Leek et al.   NATURE REVIEWS GENETICS

ELDA: Extreme limiting dilution analysis for comparing depleted and enriched populations in stem cell and other assays

(2009) Yifang Hu et al.   JOURNAL OF IMMUNOLOGICAL METHODS

CD133 expression is not selective for tumor-initiating or radioresistant cell populations in the CRC cell lines HCT-116

(2009) Claudia Dittfeld et al.   RADIOTHERAPY AND ONCOLOGY

Is CD133 a marker of metastatic colon cancer stem cells?

(2008) Mark A. LaBarge et al.   JOURNAL OF CLINICAL INVESTIGATION

CD133 expression is not restricted to stem cells, and both CD133+ and CD133– metastatic colon cancer cells initiate tumors

(2008) Sergey V. Shmelkov et al.   JOURNAL OF CLINICAL INVESTIGATION

Single-cell cloning of colon cancer stem cells reveals a multi-lineage differentiation capacity

(2008) L. Vermeulen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA