An ortholog of Plasmodium falciparum chloroquine resistance transporter (PfCRT) plays a key role in maintaining the integrity of the endolysosomal system in Toxoplasma gondii to facilitate host invasion

Intersection of endocytic and exocytic systems in Toxoplasma gondii

(2018) Olivia L. McGovern et al.   TRAFFIC

Evidence for Regulation of Hemoglobin Metabolism and Intracellular Ionic Flux by the Plasmodium falciparum Chloroquine Resistance Transporter

(2018) Andrew H. Lee et al.   Scientific Reports

A druggable secretory protein maturase of Toxoplasma essential for invasion and egress

(2017) Sunil Kumar Dogga et al.   eLife

Toxoplasma depends on lysosomal consumption of autophagosomes for persistent infection

(2017) Manlio Di Cristina et al.   Nature Microbiology

Plasmodium falciparum chloroquine resistance transporter (PfCRT) isoforms PH1 and PH2 perturb vacuolar physiology

(2016) Paul S. Callaghan et al.   MALARIA JOURNAL

Lytic Cycle of Toxoplasma gondii: 15 Years Later

(2015) Ira J. Blader et al.   Annual Review of Microbiology

Functional Comparison of 45 Naturally Occurring Isoforms of the Plasmodium falciparum Chloroquine Resistance Transporter (PfCRT)

(2015) Paul S. Callaghan et al.   BIOCHEMISTRY

Plasmodium falciparumchloroquine resistance transporter is a H+-coupled polyspecific nutrient and drug exporter

(2015) Narinobu Juge et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Toxoplasma Actin Is Required for Efficient Host Cell Invasion

(2015) Lisa L. Drewry et al.   mBio

An optimized lactate dehydrogenase release assay for screening of drug candidates in neuroscience

(2015) Simon Kaja et al.   JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS

Characterization of the Chloroquine Resistance Transporter Homologue in Toxoplasma gondii

(2014) Sally D. Warring et al.   EUKARYOTIC CELL

Calcium Entry inToxoplasma gondiiand Its Enhancing Effect of Invasion-linked Traits

(2014) Douglas A. Pace et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A vacuolar-H+-pyrophosphatase (TgVP1) is required for microneme secretion, host cell invasion, and extracellular survival ofToxoplasma gondii

(2014) Jing Liu et al.   MOLECULAR MICROBIOLOGY

Efficient Genome Engineering of Toxoplasma gondii Using CRISPR/Cas9

(2014) Saima M. Sidik et al.   PLoS One

Efficient Gene Disruption in Diverse Strains of Toxoplasma gondii Using CRISPR/CAS9

(2014) B. Shen et al.   mBio

Functional Analysis of Rhomboid Proteases during Toxoplasma Invasion

(2014) B. Shen et al.   mBio

Metabolic QTL Analysis Links Chloroquine Resistance in Plasmodium falciparum to Impaired Hemoglobin Catabolism

(2014) Ian A. Lewis et al.   PLoS Genetics

Function of Resistance Conferring Plasmodium falciparum Chloroquine Resistance Transporter Isoforms

(2013) Nicholas K. Baro et al.   BIOCHEMISTRY

Toxoplasma Sortilin-like Receptor Regulates Protein Transport and Is Essential for Apical Secretory Organelle Biogenesis and Host Infection

(2012) Pierre-Julien Sloves et al.   Cell Host & Microbe

Microneme Protein 5 Regulates the Activity ofToxoplasmaSubtilisin 1 by Mimicking a Subtilisin Prodomain

(2012) Savvas Saouros et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Non-canonical Maturation of Two Papain-family Proteases inToxoplasma gondii

(2012) Zhicheng Dou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

Intramembrane proteolysis of Toxoplasma apical membrane antigen 1 facilitates host-cell invasion but is dispensable for replication

(2012) F. Parussini et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Analysis of Chloroquine Resistance Transporter (CRT) Isoforms and Orthologues inS. cerevisiaeYeast

(2011) Nicholas K. Baro et al.   BIOCHEMISTRY

A Toxoplasma gondii protein with homology to intracellular type Na+/H+ exchangers is important for osmoregulation and invasion

(2011) Maria E. Francia et al.   EXPERIMENTAL CELL RESEARCH

TFEB Links Autophagy to Lysosomal Biogenesis

(2011) C. Settembre et al.   SCIENCE

Toxoplasma gondii protease TgSUB1 is required for cell surface processing of micronemal adhesive complexes and efficient adhesion of tachyzoites

(2010) Vanessa Lagal et al.   CELLULAR MICROBIOLOGY

Cathepsin L occupies a vacuolar compartment and is a protein maturase within the endo/exocytic system of Toxoplasma gondii

(2010) Fabiola Parussini et al.   MOLECULAR MICROBIOLOGY

Characterization of a novel organelle in Toxoplasma gondii with similar composition and function to the plant vacuole

(2010) Kildare Miranda et al.   MOLECULAR MICROBIOLOGY

Intramembrane Cleavage of AMA1 Triggers Toxoplasma to Switch from an Invasive to a Replicative Mode

(2010) J. M. Santos et al.   SCIENCE

Rhomboid 4 (ROM4) Affects the Processing of Surface Adhesins and Facilitates Host Cell Invasion by Toxoplasma gondii

(2010) Jeffrey S. Buguliskis et al.   PLoS Pathogens

Chloroquine Transport inPlasmodium falciparum. 2. Analysis of PfCRT-Mediated Drug Transport Using Proteoliposomes and a Fluorescent Chloroquine Probe

(2009) Michelle F. Paguio et al.   BIOCHEMISTRY

Tagging of Endogenous Genes in aToxoplasma gondiiStrain Lacking Ku80

(2009) My-Hang Huynh et al.   EUKARYOTIC CELL

Toxoplasma gondiiCathepsin L Is the Primary Target of the Invasion-inhibitory Compound Morpholinurea-leucyl-homophenyl-vinyl Sulfone Phenyl

(2009) Eric T. Larson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Chloroquine Transport via the Malaria Parasite's Chloroquine Resistance Transporter

(2009) R. E. Martin et al.   SCIENCE

Host cell manipulation by the human pathogen Toxoplasma gondii

(2008) J. Laliberté et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

The Prodomain ofToxoplasma gondiiGPI-Anchored Subtilase TgSUB1 Mediates its Targeting to Micronemes

(2008) Emily M. Binder et al.   TRAFFIC

MARveling at parasite invasion

(2008) Kristin M. Hager et al.   TRENDS IN PARASITOLOGY