The E3 ligase TRIM56 is a host restriction factor of Zika virus and depends on its RNA-binding activity but not miRNA regulation, for antiviral function

An evolutionary NS1 mutation enhances Zika virus evasion of host interferon induction

(2018) Hongjie Xia et al.   Nature Communications

TRIM56-mediated monoubiquitination of cGAS for cytosolic DNA sensing

(2018) Gil Ju Seo et al.   Nature Communications

Human Endometrial Stromal Cells Are Highly Permissive To Productive Infection by Zika Virus

(2017) Isabel Pagani et al.   Scientific Reports

Pivotal role for the ESCRT-II complex subunit EAP30/SNF8 in IRF3-dependent innate antiviral defense

(2017) Kattareeya Kumthip et al.   PLoS Pathogens

Zika virus evades interferon-mediated antiviral response through the co-operation of multiple nonstructural proteins in vitro

(2017) Yaoxing Wu et al.   Cell Discovery

Viperin is an important host restriction factor in control of Zika virus infection

(2017) Kylie H. Van der Hoek et al.   Scientific Reports

Zika virus as a causative agent for primary microencephaly: the evidence so far

(2016) Bor Luen Tang   ARCHIVES OF MICROBIOLOGY

Zika Virus Infection during Pregnancy in Mice Causes Placental Damage and Fetal Demise

(2016) Jonathan J. Miner et al.   CELL

A Screen of FDA-Approved Drugs for Inhibitors of Zika Virus Infection

(2016) Nicholas J. Barrows et al.   Cell Host & Microbe

Restriction of Zika Virus by Host Innate Immunity

(2016) Xuping Xie et al.   Cell Host & Microbe

Zika Virus Targets Human STAT2 to Inhibit Type I Interferon Signaling

(2016) Alesha Grant et al.   Cell Host & Microbe

A Mouse Model of Zika Virus Pathogenesis

(2016) Helen M. Lazear et al.   Cell Host & Microbe

Zika Virus Depletes Neural Progenitors in Human Cerebral Organoids through Activation of the Innate Immune Receptor TLR3

(2016) Jason Dang et al.   Cell Stem Cell

Zika Virus Infects Human Cortical Neural Progenitors and Attenuates Their Growth

(2016) Hengli Tang et al.   Cell Stem Cell

The C-Terminal Tail of TRIM56 Dictates Antiviral Restriction of Influenza A and B Viruses by Impeding Viral RNA Synthesis

(2016) Baoming Liu et al.   JOURNAL OF VIROLOGY

Zika Virus: New Clinical Syndromes and Its Emergence in the Western Hemisphere

(2016) Helen M. Lazear et al.   JOURNAL OF VIROLOGY

Pathology of congenital Zika syndrome in Brazil: a case series

(2016) Roosecelis Brasil Martines et al.   LANCET

The Brazilian Zika virus strain causes birth defects in experimental models

(2016) Fernanda R. Cugola et al.   NATURE

Zika Virus Infection with Prolonged Maternal Viremia and Fetal Brain Abnormalities

(2016) Rita W. Driggers et al.   NEW ENGLAND JOURNAL OF MEDICINE

Zika Virus Infection in Pregnant Women in Rio de Janeiro

(2016) Patrícia Brasil et al.   NEW ENGLAND JOURNAL OF MEDICINE

Zika Virus Associated with Microcephaly

(2016) Jernej Mlakar et al.   NEW ENGLAND JOURNAL OF MEDICINE

Evidence of Sexual Transmission of Zika Virus

(2016) Eric D’Ortenzio et al.   NEW ENGLAND JOURNAL OF MEDICINE

Zika virus cell tropism in the developing human brain and inhibition by azithromycin

(2016) Hanna Retallack et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of Zika Virus and Dengue Virus Dependency Factors using Functional Genomics

(2016) George Savidis et al.   Cell Reports

Biology of Zika Virus Infection in Human Skin Cells

(2015) Rodolphe Hamel et al.   JOURNAL OF VIROLOGY

Unanchored K48-Linked Polyubiquitin Synthesized by the E3-Ubiquitin Ligase TRIM6 Stimulates the Interferon-IKKε Kinase-Mediated Antiviral Response

(2014) Ricardo Rajsbaum et al.   IMMUNITY

Overlapping and Distinct Molecular Determinants Dictating the Antiviral Activities of TRIM56 against Flaviviruses and Coronavirus

(2014) B. Liu et al.   JOURNAL OF VIROLOGY

Complete replication of hepatitis B virus and hepatitis C virus in a newly developed hepatoma cell line

(2014) Darong Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Derivation and characterization of Dicer- and microRNA-deficient human cells

(2014) H. P. Bogerd et al.   RNA

Influenza A virus uses the aggresome processing machinery for host cell entry

(2014) Indranil Banerjee et al.   SCIENCE

TRIMmunity: The Roles of the TRIM E3-Ubiquitin Ligase Family in Innate Antiviral Immunity

(2013) Ricardo Rajsbaum et al.   JOURNAL OF MOLECULAR BIOLOGY

Innate Immune Sensing of Flaviviruses

(2013) Mehul S. Suthar et al.   PLoS Pathogens

TRIM56 Is an Essential Component of the TLR3 Antiviral Signaling Pathway

(2012) Yang Shen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The mammalian TRIM-NHL protein TRIM71/LIN-41 is a repressor of mRNA function

(2012) Inga Loedige et al.   NUCLEIC ACIDS RESEARCH

Trim71 cooperates with microRNAs to repress Cdkn1a expression and promote embryonic stem cell proliferation

(2012) Hao-Ming Chang et al.   Nature Communications

Genetic Characterization of Zika Virus Strains: Geographic Expansion of the Asian Lineage

(2012) Andrew D. Haddow et al.   PLoS Neglected Tropical Diseases

Activation of chemokine and inflammatory cytokine response in hepatitis C virus-infected hepatocytes depends on toll-like receptor 3 sensing of hepatitis C virus double-stranded RNA intermediates

(2011) Kui Li et al.   HEPATOLOGY

Tripartite Motif-Containing Protein 28 Is a Small Ubiquitin-Related Modifier E3 Ligase and Negative Regulator of IFN Regulatory Factor 7

(2011) Q. Liang et al.   JOURNAL OF IMMUNOLOGY

TRIM56 Is a Virus- and Interferon-Inducible E3 Ubiquitin Ligase That Restricts Pestivirus Infection

(2011) J. Wang et al.   JOURNAL OF VIROLOGY

TRIM5 is an innate immune sensor for the retrovirus capsid lattice

(2011) Thomas Pertel et al.   NATURE

Reconstitution of the RIG-I Pathway Reveals a Signaling Role of Unanchored Polyubiquitin Chains in Innate Immunity

(2010) Wenwen Zeng et al.   CELL

Viral Induction of the Zinc Finger Antiviral Protein Is IRF3-dependent but NF-κB-independent

(2010) Nan Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Tick-Borne Encephalitis Virus Delays Interferon Induction and Hides Its Double-Stranded RNA in Intracellular Membrane Vesicles

(2010) A. K. Overby et al.   JOURNAL OF VIROLOGY

Antiviral activities of ISG20 in positive-strand RNA virus infections

(2010) Zhi Zhou et al.   VIROLOGY

TRIM-NHL Proteins Take on miRNA Regulation

(2009) Inga Loedige et al.   CELL

The TRIM-NHL Protein TRIM32 Activates MicroRNAs and Prevents Self-Renewal in Mouse Neural Progenitors

(2009) Jens C. Schwamborn et al.   CELL

Toll-Like Receptor 3 Mediates Establishment of an Antiviral State against Hepatitis C Virus in Hepatoma Cells

(2009) N. Wang et al.   JOURNAL OF VIROLOGY