Innate Immune Sensing of Flaviviruses

High plasma levels of soluble ST2 but not its ligand IL-33 is associated with severe forms of pediatric dengue

(2013) Christian D. Guerrero et al.   CYTOKINE

IL-1R1 is required for dendritic cell–mediated T cell reactivation within the CNS during West Nile virus encephalitis

(2013) Douglas M. Durrant et al.   JOURNAL OF EXPERIMENTAL MEDICINE

West Nile virus infection and immunity

(2013) Mehul S. Suthar et al.   NATURE REVIEWS MICROBIOLOGY

A Systems Biology Approach Reveals that Tissue Tropism to West Nile Virus Is Regulated by Antiviral Genes and Innate Immune Cellular Processes

(2013) Mehul S. Suthar et al.   PLoS Pathogens

CLEC5A is critical for dengue virus-induced inflammasome activation in human macrophages

(2012) M.-F. Wu et al.   BLOOD

Identification of multiple RIG-I-specific pathogen associated molecular patterns within the West Nile virus genome and antigenome

(2012) Jennifer German Shipley et al.   VIROLOGY

Human Arboviral Encephalitis

(2012) Robert S. Rust   Seminars in Pediatric Neurology

IL-1β Signaling Promotes CNS-Intrinsic Immune Control of West Nile Virus Infection

(2012) Hilario J. Ramos et al.   PLoS Pathogens

DENV Inhibits Type I IFN Production in Infected Cells by Cleaving Human STING

(2012) Sebastian Aguirre et al.   PLoS Pathogens

Immune Signaling by RIG-I-like Receptors

(2011) Yueh-Ming Loo et al.   IMMUNITY

Modulation of Inflammasome Pathways by Bacterial and Viral Pathogens

(2011) M. Lamkanfi et al.   JOURNAL OF IMMUNOLOGY

RIG-I, MDA5 and TLR3 Synergistically Play an Important Role in Restriction of Dengue Virus Infection

(2011) A. M. A. Nasirudeen et al.   PLoS Neglected Tropical Diseases

Pro-inflammatory cytokines derived from West Nile virus (WNV)-infected SK-N-SH cells mediate neuroinflammatory markers and neuronal death

(2010) Mukesh Kumar et al.   Journal of Neuroinflammation

RNA Structures Required for Production of Subgenomic Flavivirus RNA

(2010) A. Funk et al.   JOURNAL OF VIROLOGY

Dengue Virus Inhibits the Production of Type I Interferon in Primary Human Dendritic Cells

(2010) J. R. Rodriguez-Madoz et al.   JOURNAL OF VIROLOGY

The Endoplasmic Reticulum Provides the Membrane Platform for Biogenesis of the Flavivirus Replication Complex

(2010) Leah K. Gillespie et al.   JOURNAL OF VIROLOGY

RNase L releases a small RNA from HCV RNA that refolds into a potent PAMP

(2010) K. Malathi et al.   RNA

Nonstructural NS1 proteins of several mosquito-borne Flavivirus do not inhibit TLR3 signaling

(2010) Cécile Baronti et al.   VIROLOGY

IPS-1 Is Essential for the Control of West Nile Virus Infection and Immunity

(2010) Mehul S. Suthar et al.   PLoS Pathogens

Composition and Three-Dimensional Architecture of the Dengue Virus Replication and Assembly Sites

(2009) Sonja Welsch et al.   Cell Host & Microbe

Cardif-Mediated Signaling Controls the Initial Innate Response to Dengue Virus In Vivo

(2009) S. T. Perry et al.   JOURNAL OF VIROLOGY

Multiplex cytokine profile from dengue patients: MIP-1beta and IFN-gamma as predictive factors for severity

(2008) Fernando A Bozza et al.   BMC INFECTIOUS DISEASES

Human TLR3 recognizes dengue virus and modulates viral replicationin vitro

(2008) Yi-Ting Tsai et al.   CELLULAR MICROBIOLOGY

West Nile Virus Nonstructural Protein 1 Inhibits TLR3 Signal Transduction

(2008) J. R. Wilson et al.   JOURNAL OF VIROLOGY

West Nile virus genome cyclization and RNA replication require two pairs of long-distance RNA interactions

(2008) Bo Zhang et al.   VIROLOGY