LF4/MOK and a CDK-related kinase regulate the number and length of cilia in Tetrahymena

The kinases male germ cell-associated kinase and cell cycle-related kinase regulate kinesin-2 motility in Caenorhabditis elegans neuronal cilia

(2018) Peishan Yi et al.   TRAFFIC

Ciliary Length Sensing Regulates IFT Entry via Changes in FLA8/KIF3B Phosphorylation to Control Ciliary Assembly

(2018) Yinwen Liang et al.   CURRENT BIOLOGY

The Hippo Pathway Maintains the Equatorial Division Plane in the CiliateTetrahymena

(2017) Yu-Yang Jiang et al.   GENETICS

Cell Cycle-Related Kinase (CCRK) regulates ciliogenesis and Hedgehog signaling in mice

(2017) Ashley Snouffer et al.   PLoS Genetics

IFT trains in different stages of assembly queue at the ciliary base for consecutive release into the cilium

(2017) Jenna L Wingfield et al.   eLife

The Hippo Pathway Maintains the Equatorial Division Plane in the CiliateTetrahymena

(2017) Yu-Yang Jiang et al.   GENETICS

Mechanism of ciliary disassembly

(2016) Yinwen Liang et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Reduction of ciliary length through pharmacologic or genetic inhibition of CDK5 attenuates polycystic kidney disease in a model of nephronophthisis

(2016) Hervé Husson et al.   HUMAN MOLECULAR GENETICS

A NIMA-related kinase, CNK4, regulates ciliary stability and length

(2016) Dan Meng et al.   MOLECULAR BIOLOGY OF THE CELL

Cellular Mechanisms of Ciliary Length Control

(2016) Jacob Keeling et al.   Cells

A Systematic Comparison of Mathematical Models for Inherent Measurement of Ciliary Length: How a Cell Can Measure Length and Volume

(2015) William B. Ludington et al.   BIOPHYSICAL JOURNAL

Cell cycle-dependent ubiquitylation and destruction of NDE1 by CDK5-FBW7 regulates ciliary length

(2015) D. Maskey et al.   EMBO JOURNAL

A missense mutation in DCDC2 causes human recessive deafness DFNB66, likely by interfering with sensory hair cell and supporting cell cilia length regulation

(2015) M'hamed Grati et al.   HUMAN MOLECULAR GENETICS

Tubulin transport by IFT is upregulated during ciliary growth by a cilium-autonomous mechanism

(2015) Julie M. Craft et al.   JOURNAL OF CELL BIOLOGY

MKS1 regulates ciliary INPP5E levels in Joubert syndrome

(2015) Gisela G Slaats et al.   JOURNAL OF MEDICAL GENETICS

Kinesin-13 regulates the quantity and quality of tubulin inside cilia

(2015) Krishna Kumar Vasudevan et al.   MOLECULAR BIOLOGY OF THE CELL

The CSC proteins FAP61 and FAP251 build the basal substructures of radial spoke 3 in cilia

(2015) Paulina Urbanska et al.   MOLECULAR BIOLOGY OF THE CELL

Reduced tubulin polyglutamylation suppresses flagellar shortness in Chlamydomonas

(2015) Tomohiro Kubo et al.   MOLECULAR BIOLOGY OF THE CELL

I-TASSER server: new development for protein structure and function predictions

(2015) Jianyi Yang et al.   NUCLEIC ACIDS RESEARCH

JPred4: a protein secondary structure prediction server

(2015) Alexey Drozdetskiy et al.   NUCLEIC ACIDS RESEARCH

Mutations in DYNC2LI1 disrupt cilia function and cause short rib polydactyly syndrome

(2015) S. Paige Taylor et al.   Nature Communications

A NIMA-Related Kinase Suppresses the Flagellar Instability Associated with the Loss of Multiple Axonemal Structures

(2015) Huawen Lin et al.   PLoS Genetics

FLA8/KIF3B Phosphorylation Regulates Kinesin-II Interaction with IFT-B to Control IFT Entry and Turnaround

(2014) Yinwen Liang et al.   DEVELOPMENTAL CELL

Regulation of Cilium Length and Intraflagellar Transport by the RCK-Kinases ICK and MOK in Renal Epithelial Cells

(2014) Joost R. Broekhuis et al.   PLoS One

Intestinal cell kinase, a protein associated with endocrine-cerebro-osteodysplasia syndrome, is a key regulator of cilia length and Hedgehog signaling

(2014) H. Moon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural and evolutionary adaptation of rhoptry kinases and pseudokinases, a family of coccidian virulence factors

(2013) Eric Talevich et al.   BMC EVOLUTIONARY BIOLOGY

A Differential Cargo-Loading Model of Ciliary Length Regulation by IFT

(2013) Kathryne N. Wren et al.   CURRENT BIOLOGY

The Kinases LF4 and CNK2 Control Ciliary Length by Feedback Regulation of Assembly and Disassembly Rates

(2013) Laura K. Hilton et al.   CURRENT BIOLOGY

CCRK depletion inhibits glioblastoma cell proliferation in a cilium-dependent manner

(2013) Ying Yang et al.   EMBO REPORTS

Puromycin resistance gene as an effective selection marker for ciliate Tetrahymena

(2013) Masaaki Iwamoto et al.   GENE

CDKL5 regulates flagellar length and localizes to the base of the flagella in Chlamydomonas

(2013) Lai-Wa Tam et al.   MOLECULAR BIOLOGY OF THE CELL

Avalanche-like behavior in ciliary import

(2013) W. B. Ludington et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

KIF19A Is a Microtubule-Depolymerizing Kinesin for Ciliary Length Control

(2012) Shinsuke Niwa et al.   DEVELOPMENTAL CELL

Intestinal Cell Kinase (ICK) Promotes Activation of mTOR Complex 1 (mTORC1) through Phosphorylation of Raptor Thr-908

(2012) Di Wu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

COFACTOR: an accurate comparative algorithm for structure-based protein function annotation

(2012) Ambrish Roy et al.   NUCLEIC ACIDS RESEARCH

Transcriptome Analysis of the Model Protozoan, Tetrahymena thermophila, Using Deep RNA Sequencing

(2012) Jie Xiong et al.   PLoS One

Distinct Functional Roles of β-Tubulin Isotypes in Microtubule Arrays of Tetrahymena thermophila, a Model Single-Celled Organism

(2012) Sandra Pucciarelli et al.   PLoS One

NEK1 Mutations Cause Short-Rib Polydactyly Syndrome Type Majewski

(2011) Christian Thiel et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Exome Sequencing and cis-Regulatory Mapping Identify Mutations in MAK, a Gene Encoding a Regulator of Ciliary Length, as a Cause of Retinitis Pigmentosa

(2011) Rıza Köksal Özgül et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Structural and evolutionary divergence of eukaryotic protein kinases in Apicomplexa

(2011) Eric Talevich et al.   BMC EVOLUTIONARY BIOLOGY

The Cryptosporidium parvum Kinome

(2011) Jennifer D Artz et al.   BMC GENOMICS

Mechanisms regulating cilia growth and cilia function in endothelial cells

(2011) Shakila Abdul-Majeed et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Transcriptional profiling of C. elegans DAF-19 uncovers a ciliary base-associated protein and a CDK/CCRK/LF2p-related kinase required for intraflagellar transport

(2011) Prasad Phirke et al.   DEVELOPMENTAL BIOLOGY

Stages of ciliogenesis and regulation of ciliary length

(2011) Prachee Avasthi et al.   DIFFERENTIATION

Mutations in KIF7 link Joubert syndrome with Sonic Hedgehog signaling and microtubule dynamics

(2011) Claudia Dafinger et al.   JOURNAL OF CLINICAL INVESTIGATION

The Ime2 protein kinase family in fungi: more duties than just meiosis

(2011) Stefan Irniger   MOLECULAR MICROBIOLOGY

Male germ cell-associated kinase is overexpressed in prostate cancer cells and causes mitotic defects via deregulation of APC/CCDH1

(2011) L-Y Wang et al.   ONCOGENE

Accelerated Profile HMM Searches

(2011) Sean R. Eddy   PLoS Computational Biology

Establishment of a Cre/loxP recombination system for N-terminal epitope tagging of genes in Tetrahymena

(2010) Clara Busch et al.   BMC MICROBIOLOGY

Epilepsy caused by CDKL5 mutations

(2010) Maija Castrén et al.   EUROPEAN JOURNAL OF PAEDIATRIC NEUROLOGY

Modules for C-terminal epitope tagging of Tetrahymena genes

(2010) Kensuke Kataoka et al.   JOURNAL OF MICROBIOLOGICAL METHODS

Chlamydomonas IFT70/CrDYF-1 Is a Core Component of IFT Particle Complex B and Is Required for Flagellar Assembly

(2010) Zhen-Chuan Fan et al.   MOLECULAR BIOLOGY OF THE CELL

Negative regulation of ciliary length by ciliary male germ cell-associated kinase (Mak) is required for retinal photoreceptor survival

(2010) Y. Omori et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Rapid detection, classification and accurate alignment of up to a million or more related protein sequences

(2009) Andrew F. Neuwald   BIOINFORMATICS

DYF-1 Is Required for Assembly of the Axoneme inTetrahymena thermophila

(2009) Drashti Dave et al.   EUKARYOTIC CELL

Ciliary and centrosomal defects associated with mutation and depletion of the Meckel syndrome genes MKS1 and MKS3

(2009) Rachaneekorn Tammachote et al.   HUMAN MOLECULAR GENETICS

Intraflagellar transport particle size scales inversely with flagellar length: revisiting the balance-point length control model

(2009) Benjamin D. Engel et al.   JOURNAL OF CELL BIOLOGY

The ubiquitin conjugation system is involved in the disassembly of cilia and flagella

(2009) Kaiyao Huang et al.   JOURNAL OF CELL BIOLOGY

A microtubule depolymerizing kinesin functions during both flagellar disassembly and flagellar assembly in Chlamydomonas

(2009) T. Piao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

I-TASSER: Fully automated protein structure prediction in CASP8

(2009) Yang Zhang   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

High efficiency transformation of Tetrahymena using a codon-optimized neomycin resistance gene

(2008) Kazufumi Mochizuki   GENE

Congenital disease SNPs target lineage specific structural elements in protein kinases

(2008) Ali Torkamani et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Characterization of mutations induced by N-methyl-N′-nitro-N-nitrosoguanidine in an industrial Corynebacterium glutamicum strain

(2007) Junko Ohnishi et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS