Attenuation of chronic antiviral T-cell responses through constitutive COX2-dependent prostanoid synthesis by lymph node fibroblasts
Published 2019 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Attenuation of chronic antiviral T-cell responses through constitutive COX2-dependent prostanoid synthesis by lymph node fibroblasts
Authors
Keywords
T cells, Cytotoxic T cells, Spleen, Mouse models, Flow cytometry, Inflammation, Lymph nodes, Immune response
Journal
PLOS BIOLOGY
Volume 17, Issue 7, Pages e3000072
Publisher
Public Library of Science (PLoS)
Online
2019-07-16
DOI
10.1371/journal.pbio.3000072
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- CD8 T Cell Exhaustion in Chronic Infection and Cancer: Opportunities for Interventions
- (2018) Masao Hashimoto et al. Annual Review of Medicine
- NK Cells Stimulate Recruitment of cDC1 into the Tumor Microenvironment Promoting Cancer Immune Control
- (2018) Jan P. Böttcher et al. CELL
- The human lymph node microenvironment unilaterally regulates T-cell activation and differentiation
- (2018) Konstantin Knoblich et al. PLOS BIOLOGY
- Fibroblastic reticular cells of the lymphoid tissues modulate T cell activation threshold during homeostasis via hyperactive cyclooxygenase-2/prostaglandin E2 axis
- (2017) Miao Yu et al. Scientific Reports
- Cyclooxygenase-Dependent Tumor Growth through Evasion of Immunity
- (2015) Santiago Zelenay et al. CELL
- Prostaglandin E2 and programmed cell death 1 signaling coordinately impair CTL function and survival during chronic viral infection
- (2015) Jonathan H Chen et al. NATURE MEDICINE
- Lymph node stromal cells acquire peptide–MHCII complexes from dendritic cells and induce antigen-specific CD4+T cell tolerance
- (2014) Juan Dubrot et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Lymph node fibroblastic reticular cell transplants show robust therapeutic efficacy in high-mortality murine sepsis
- (2014) A. L. Fletcher et al. Science Translational Medicine
- Maturation of Lymph Node Fibroblastic Reticular Cells from Myofibroblastic Precursors Is Critical for Antiviral Immunity
- (2013) Qian Chai et al. IMMUNITY
- Oncology Meets Immunology: The Cancer-Immunity Cycle
- (2013) Daniel S. Chen et al. IMMUNITY
- iNOS signaling interacts with COX-2 pathway in colonic fibroblasts
- (2012) Yingting Zhu et al. EXPERIMENTAL CELL RESEARCH
- Stromal and hematopoietic cells in secondary lymphoid organs: partners in immunity
- (2012) Deepali Malhotra et al. IMMUNOLOGICAL REVIEWS
- Multifaceted roles of PGE2 in inflammation and cancer
- (2012) Masako Nakanishi et al. Seminars in Immunopathology
- Positive and negative regulation of T cell responses by fibroblastic reticular cells within paracortical regions of lymph nodes
- (2012) Stefanie Siegert et al. Frontiers in Immunology
- Skin fibroblasts are potent suppressors of inflammation in experimental arthritis
- (2011) C. Bouffi et al. ANNALS OF THE RHEUMATIC DISEASES
- Modulation of human T-cell functions by reactive nitrogen species
- (2011) Tihana Kasic et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Prostaglandin E2 and T cells: friends or foes?
- (2011) Vinatha Sreeramkumar et al. IMMUNOLOGY AND CELL BIOLOGY
- Regulation of Immune Responses by Prostaglandin E2
- (2011) P. Kalinski JOURNAL OF IMMUNOLOGY
- Regulated release of nitric oxide by nonhematopoietic stroma controls expansion of the activated T cell pool in lymph nodes
- (2011) Veronika Lukacs-Kornek et al. NATURE IMMUNOLOGY
- Fibroblastic Reticular Cells From Lymph Nodes Attenuate T Cell Expansion by Producing Nitric Oxide
- (2011) Stefanie Siegert et al. PLoS One
- Regulation of T Cell Priming by Lymphoid Stroma
- (2011) Omar Khan et al. PLoS One
- PD-L1 has distinct functions in hematopoietic and nonhematopoietic cells in regulating T cell responses during chronic infection in mice
- (2010) Scott N. Mueller et al. JOURNAL OF CLINICAL INVESTIGATION
- Lymph node fibroblastic reticular cells directly present peripheral tissue antigen under steady-state and inflammatory conditions
- (2010) Anne L. Fletcher et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Prostanoids and inflammation: a new concept arising from receptor knockout mice
- (2009) Shuh Narumiya JOURNAL OF MOLECULAR MEDICINE-JMM
- Cyclooxygenase-2 in mucosal DC mediates induction of regulatory T cells in the intestine through suppression of IL-4
- (2009) F Broere et al. Mucosal Immunology
- Complete but curtailed T-cell response to very low-affinity antigen
- (2009) Dietmar Zehn et al. NATURE
- Restoration of lymphoid organ integrity through the interaction of lymphoid tissue–inducer cells with stroma of the T cell zone
- (2008) Elke Scandella et al. NATURE IMMUNOLOGY
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started