3D Reconstruction of the Neurovascular Unit Reveals Differential Loss of Cholinergic Innervation in the Cortex and Hippocampus of the Adult Mouse Brain

Cerebrovascular Smooth Muscle Cells as the Drivers of Intramural Periarterial Drainage of the Brain

(2019) Roxana Aldea et al.   Frontiers in Aging Neuroscience

Convective influx/glymphatic system: tracers injected into the CSF enter and leave the brain along separate periarterial basement membrane pathways

(2018) Nazira J. Albargothy et al.   ACTA NEUROPATHOLOGICA

Impact of pulse pressure on cerebrovascular events leading to age-related cognitive decline

(2018) Nathalie Thorin-Trescases et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

The cholinergic system in the pathophysiology and treatment of Alzheimer’s disease

(2018) Harald Hampel et al.   BRAIN

The effects of cerebral amyloid angiopathy on integrity of the blood-brain barrier

(2018) Shino Magaki et al.   NEUROBIOLOGY OF AGING

Noradrenergic Sympathetic Sprouting and Cholinergic Reinnervation Maintains Non-Amyloidogenic Processing of AβPP

(2018) Amy R. Nelson et al.   JOURNAL OF ALZHEIMERS DISEASE

Neurovascular Specifications in the Alzheimer-Like Brain of Mice Affected by Focal Cerebral Ischemia: Implications for Future Therapies

(2017) Dominik Michalski et al.   JOURNAL OF ALZHEIMERS DISEASE

Impact of Altered Cholinergic Tones on the Neurovascular Coupling Response to Whisker Stimulation

(2017) Clotilde Lecrux et al.   JOURNAL OF NEUROSCIENCE

The Neurovascular Unit Coming of Age: A Journey through Neurovascular Coupling in Health and Disease

(2017) Costantino Iadecola   NEURON

Inhibiting medial septal cholinergic neurons with DREADD alleviated anxiety-like behaviors in mice

(2017) Yu Zhang et al.   NEUROSCIENCE LETTERS

Generation of a whole-brain atlas for the cholinergic system and mesoscopic projectome analysis of basal forebrain cholinergic neurons

(2017) Xiangning Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Reduced basal forebrain atrophy progression in a randomized Donepezil trial in prodromal Alzheimer’s disease

(2017) Enrica Cavedo et al.   Scientific Reports

Vascular, glial, and lymphatic immune gateways of the central nervous system

(2016) Britta Engelhardt et al.   ACTA NEUROPATHOLOGICA

Basal Forebrain Cholinergic Neurons Primarily Contribute to Inhibition of Electroencephalogram Delta Activity, Rather Than Inducing Behavioral Wakefulness in Mice

(2016) Li Chen et al.   NEUROPSYCHOPHARMACOLOGY

Basal forebrain degeneration precedes and predicts the cortical spread of Alzheimer’s pathology

(2016) Taylor W. Schmitz et al.   Nature Communications

Early role of vascular dysregulation on late-onset Alzheimer’s disease based on multifactorial data-driven analysis

(2016) Y. Iturria-Medina et al.   Nature Communications

Central Cholinergic Neurons Are Rapidly Recruited by Reinforcement Feedback

(2015) Balázs Hangya et al.   CELL

Silencing of Cholinergic Basal Forebrain Neurons Using Archaerhodopsin Prolongs Slow-Wave Sleep in Mice

(2015) Yu-Feng Shi et al.   PLoS One

The Cerebrovascular Basement Membrane: Role in the Clearance of β-amyloid and Cerebral Amyloid Angiopathy

(2014) Alan W. J. Morris et al.   Frontiers in Aging Neuroscience

Complete morphologies of basal forebrain cholinergic neurons in the mouse

(2014) Hao Wu et al.   eLife

A Critical Role for the Vascular Endothelium in Functional Neurovascular Coupling in the Brain

(2014) Brenda R. Chen et al.   Journal of the American Heart Association

Regional differences in the morphological and functional effects of aging on cerebral basement membranes and perivascular drainage of amyloid-β from the mouse brain

(2013) Cheryl A. Hawkes et al.   AGING CELL

β-Amyloid, Cholinergic Transmission, and Cerebrovascular System - A Developmental Study in a Mouse Model of Alzheimer's Disease

(2013) Elena Kuznetsova et al.   CURRENT PHARMACEUTICAL DESIGN

Rapid β-Amyloid Deposition and Cognitive Impairment After Cholinergic Denervation in APP/PS1 Mice

(2013) Juan Jose Ramos-Rodriguez et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Lesions of the Basal Forebrain Cholinergic System in Mice Disrupt Idiothetic Navigation

(2013) Adam S. Hamlin et al.   PLoS One

Cholinergic degeneration is associated with increased plaque deposition and cognitive impairment in APPswe/PS1dE9 mice

(2012) Bettina Laursen et al.   BEHAVIOURAL BRAIN RESEARCH

Low-density Lipoprotein Receptor Represents an Apolipoprotein E-independent Pathway of Aβ Uptake and Degradation by Astrocytes

(2012) Jacob M. Basak et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

LRP1 in Brain Vascular Smooth Muscle Cells Mediates Local Clearance of Alzheimer's Amyloid- 

(2012) T. Kanekiyo et al.   JOURNAL OF NEUROSCIENCE

Diffusion-weighted magnetic resonance imaging detection of basal forebrain cholinergic degeneration in a mouse model

(2012) Georg M. Kerbler et al.   NEUROIMAGE

A Paravascular Pathway Facilitates CSF Flow Through the Brain Parenchyma and the Clearance of Interstitial Solutes, Including Amyloid  

(2012) J. J. Iliff et al.   Science Translational Medicine

Extracellular matrix and matrix receptors in blood-brain barrier formation and stroke

(2011) Kim M. Baeten et al.   Developmental Neurobiology

Hypothetical model of dynamic biomarkers of the Alzheimer's pathological cascade

(2009) Clifford R Jack et al.   LANCET NEUROLOGY

Cerebral amyloid angiopathy and its relationship to Alzheimer’s disease

(2008) Dietmar Rudolf Thal et al.   ACTA NEUROPATHOLOGICA

Structural Changes in Alzheimers Disease Brain Microvessels

(2008) Alexander Christov et al.   Current Alzheimer Research

Perivascular Spaces and the Two Steps to Neuroinflammation

(2008) Trevor Owens et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY