Intra-articularly injected mesenchymal stem cells promote cartilage regeneration, but do not permanently engraft in distant organs

Human umbilical cord Wharton's jelly mesenchymal stem cells combined with an acellular cartilage extracellular matrix scaffold improve cartilage repair compared with microfracture in a caprine model

(2018) Y. Zhang et al.   OSTEOARTHRITIS AND CARTILAGE

Immunomodulation By Therapeutic Mesenchymal Stromal Cells (MSC) Is Triggered Through Phagocytosis of MSC By Monocytic Cells

(2018) Samantha F.H. de Witte et al.   STEM CELLS

Oxidative stress preconditioning of mouse perivascular myogenic progenitors selects a subpopulation of cells with a distinct survival advantage in vitro and in vivo

(2018) Cesare Gargioli et al.   Cell Death & Disease

The limited application of stem cells in medicine: a review

(2018) Jordan Poulos   Stem Cell Research & Therapy

Timing of Intra-Articular Injection of Synovial Mesenchymal Stem Cells Affects Cartilage Restoration in a Partial Thickness Cartilage Defect Model in Rats

(2018) Takahiro Enomoto et al.   Cartilage

Cartilage regeneration using arthroscopic flushing fluid-derived mesenchymal stem cells encapsulated in a one-step rapid cross-linked hydrogel

(2018) Jun Li et al.   Acta Biomaterialia

In situ immune response and mechanisms of cell damage in central nervous system of fatal cases microcephaly by Zika virus

(2018) Raimunda S. S. Azevedo et al.   Scientific Reports

Single-stage cell-based cartilage repair in a rabbit model: cell tracking and in vivo chondrogenesis of human umbilical cord blood-derived mesenchymal stem cells and hyaluronic acid hydrogel composite

(2017) Y.B. Park et al.   OSTEOARTHRITIS AND CARTILAGE

Intra-articular injection of expanded autologous bone marrow mesenchymal cells in moderate and severe knee osteoarthritis is safe: a phase I/II study

(2017) Mahasen Al-Najar et al.   Journal of Orthopaedic Surgery and Research

Ror2 signaling regulates Golgi structure and transport through IFT20 for tumor invasiveness

(2017) Michiru Nishita et al.   Scientific Reports

Mesenchymal stem cells in regenerative medicine: Focus on articular cartilage and intervertebral disc regeneration

(2016) Stephen M. Richardson et al.   METHODS

Not single but periodic injections of synovial mesenchymal stem cells maintain viable cells in knees and inhibit osteoarthritis progression in rats

(2016) N. Ozeki et al.   OSTEOARTHRITIS AND CARTILAGE

In vivo human adipose-derived mesenchymal stem cell tracking after intra-articular delivery in a rat osteoarthritis model

(2016) Meng Li et al.   Stem Cell Research & Therapy

A dose response analysis of a specific bone marrow concentrate treatment protocol for knee osteoarthritis

(2015) Christopher J. Centeno et al.   BMC MUSCULOSKELETAL DISORDERS

Mesenchymal Stem Cells for Treating Articular Cartilage Defects and Osteoarthritis

(2015) Yu Wang et al.   CELL TRANSPLANTATION

Mesenchymal stem cell therapy for knee osteoarthritis: 5 years follow-up of three patients

(2015) Fereydoun Davatchi et al.   International Journal of Rheumatic Diseases

Survival and Biodistribution of Xenogenic Adipose Mesenchymal Stem Cells Is Not Affected by the Degree of Inflammation in Arthritis

(2015) Karine Toupet et al.   PLoS One

Insensitivity of Human iPS Cells-Derived Mesenchymal Stem Cells to Interferon-γ-induced HLA Expression Potentiates Repair Efficiency of Hind Limb Ischemia in Immune Humanized NOD Scid Gamma Mice

(2015) Yue-Qi Sun et al.   STEM CELLS

Pharmacokinetics and In Vivo Fate of Intra-Articularly Transplanted Human Bone Marrow-Derived Clonal Mesenchymal Stem Cells

(2015) Gayong Shim et al.   STEM CELLS AND DEVELOPMENT

Treatment of Knee Osteoarthritis With Allogeneic Bone Marrow Mesenchymal Stem Cells

(2015) Aurelio Vega et al.   TRANSPLANTATION

Activation of NRG1-ERBB4 signaling potentiates mesenchymal stem cell-mediated myocardial repairs following myocardial infarction

(2015) X Liang et al.   Cell Death & Disease

Intra-Articular Injection of Mesenchymal Stem Cells for the Treatment of Osteoarthritis of the Knee: A Proof-of-Concept Clinical Trial

(2014) Chris Hyunchul Jo et al.   STEM CELLS

Mesenchymal Stem Cell Delivery Routes and Fate

(2014) Andreas Kurtz   International Journal of Stem Cells

Long-Term Detection of Human Adipose-Derived Mesenchymal Stem Cells After Intraarticular Injection in SCID Mice

(2013) Karine Toupet et al.   ARTHRITIS AND RHEUMATISM

Safety of intra-articular cell-therapy with culture-expanded stem cells in humans: a systematic literature review

(2013) C.M.M. Peeters et al.   OSTEOARTHRITIS AND CARTILAGE

Intra-articular delivery of adipose derived stromal cells attenuates osteoarthritis progression in an experimental rabbit model

(2013) Giovanna Desando et al.   ARTHRITIS RESEARCH & THERAPY

Regulation of cell proliferation of human induced pluripotent stem cell-derived mesenchymal stem cells via ether-à-go-go 1 (hEAG1) potassium channel

(2012) Jiao Zhang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Antiinflammatory and chondroprotective effects of intraarticular injection of adipose-derived stem cells in experimental osteoarthritis

(2012) Menno ter Huurne et al.   ARTHRITIS AND RHEUMATISM

Safety of Cell Therapy with Mesenchymal Stromal Cells (SafeCell): A Systematic Review and Meta-Analysis of Clinical Trials

(2012) Manoj M. Lalu et al.   PLoS One

Unlike Bone, Cartilage Regeneration Remains Elusive

(2012) D. J. Huey et al.   SCIENCE

Direct transplantation of mesenchymal stem cells into the knee joints of Hartley strain guinea pigs with spontaneous osteoarthritis

(2012) Mitsuhiko Sato et al.   ARTHRITIS RESEARCH & THERAPY

Mesenchymal stem cells for cartilage repair in osteoarthritis

(2012) Pawan K Gupta et al.   Stem Cell Research & Therapy

Mouse Bone Marrow-Derived Mesenchymal Stromal Cells Turn Activated Macrophages into a Regulatory-Like Profile

(2010) Julian Maggini et al.   PLoS One

Human Gingiva-Derived Mesenchymal Stem Cells Elicit Polarization of M2 Macrophages and Enhance Cutaneous Wound Healing

(2010) Qun-Zhou Zhang et al.   STEM CELLS

Mesenchymal stem cell–educated macrophages: A novel type of alternatively activated macrophages

(2009) Jaehyup Kim et al.   EXPERIMENTAL HEMATOLOGY

Intra-articular Injected Synovial Stem Cells Differentiate into Meniscal Cells Directly and Promote Meniscal Regeneration Without Mobilization to Distant Organs in Rat Massive Meniscal Defect

(2009) Masafumi Horie et al.   STEM CELLS