A new regulatory mechanism for Raf kinase activation, retinoic acid-bound Crabp1

CRABP1 protects the heart from isoproterenol-induced acute and chronic remodeling

(2018) Sung Wook Park et al.   JOURNAL OF ENDOCRINOLOGY

Cellular Retinoic Acid–Binding Protein 1 Modulates Stem Cell Proliferation to Affect Learning and Memory in Male Mice

(2017) Yu-Lung Lin et al.   ENDOCRINOLOGY

Cellular retinoid binding-proteins, CRBP, CRABP, FABP5: Effects on retinoid metabolism, function and related diseases

(2017) Joseph L. Napoli   PHARMACOLOGY & THERAPEUTICS

Drugging RAS: Know the enemy

(2017) Bjoern Papke et al.   SCIENCE

A Small Molecule RAS-Mimetic Disrupts RAS Association with Effector Proteins to Block Signaling

(2016) Sai Krishna Athuluri-Divakar et al.   CELL

All trans-retinoic acid analogs promote cancer cell apoptosis through non-genomic Crabp1 mediating ERK1/2 phosphorylation

(2016) Shawna D. Persaud et al.   Scientific Reports

Retinoic acid signaling and mouse embryonic stem cell differentiation: Cross talk between genomic and non-genomic effects of RA

(2015) Cécile Rochette-Egly   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Epigenetic priming of non-small cell lung cancer cell lines to the antiproliferative and differentiating effects of all-trans retinoic acid

(2015) Gabriele Greve et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

Regulation of RAF protein kinases in ERK signalling

(2015) Hugo Lavoie et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

NMRFAM-SPARKY: enhanced software for biomolecular NMR spectroscopy

(2014) Woonghee Lee et al.   BIOINFORMATICS

All-transretinoic acid induces cell-cycle arrest in human cutaneous squamous carcinoma cells by inhibiting the mitogen-activated protein kinase-activated protein 1 pathway

(2014) M.-l. Zhang et al.   CLINICAL AND EXPERIMENTAL DERMATOLOGY

Drugging the undruggable RAS: Mission Possible?

(2014) Adrienne D. Cox et al.   NATURE REVIEWS DRUG DISCOVERY

Allosteric Activation of Functionally Asymmetric RAF Kinase Dimers

(2013) Jiancheng Hu et al.   CELL

The Role of Aromatic–Aromatic Interactions in Strand–Strand Stabilization of β-Sheets

(2013) Ivan L. Budyak et al.   JOURNAL OF MOLECULAR BIOLOGY

A Comprehensive Survey of Ras Mutations in Cancer

(2012) I. A. Prior et al.   CANCER RESEARCH

Calcium/calmodulin-dependent protein kinase II (CaMKII) phosphorylates Raf-1 at serine 338 and mediates Ras-stimulated Raf-1 activation

(2012) Marcella Salzano et al.   CELL CYCLE

Cellular retinoic acid binding protein I mediates rapid non-canonical activation of ERK1/2 by all-trans retinoic acid

(2012) Shawna D. Persaud et al.   CELLULAR SIGNALLING

ERK1/2 MAP kinases: Structure, function, and regulation

(2012) Robert Roskoski   PHARMACOLOGICAL RESEARCH

Activation and Function of the MAPKs and Their Substrates, the MAPK-Activated Protein Kinases

(2011) M. Cargnello et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Nuclear retinoic acid receptors: Conductors of the retinoic acid symphony during development

(2011) Eric Samarut et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Promyelocytic Leukemia Protein in Retinoic Acid-Induced Chromatin Remodeling of Oct4 Gene Promoter

(2011) Ya-Shan Chuang et al.   STEM CELLS

RAF protein-serine/threonine kinases: Structure and regulation

(2010) Robert Roskoski   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

AKAP-Lbc enhances cyclic AMP control of the ERK1/2 cascade

(2010) F. Donelson Smith et al.   NATURE CELL BIOLOGY

Identification of the B-Raf/Mek/Erk MAP kinase pathway as a target for all-trans retinoic acid during skin cancer promotion

(2009) Satish B Cheepala et al.   Molecular Cancer

Probabilistic Interaction Network of Evidence Algorithm and its Application to Complete Labeling of Peak Lists from Protein NMR Spectroscopy

(2009) Arash Bahrami et al.   PLoS Computational Biology

Retinoic Acid Synthesis and Signaling during Early Organogenesis

(2008) Gregg Duester   CELL

Modulation of lysine acetylation-stimulated repressive activity by Erk2-mediated phosphorylation of RIP140 in adipocyte differentiation

(2008) Ping-Chih Ho et al.   CELLULAR SIGNALLING

Application of Pulsed Field Gradient NMR with High Gradient Strength for Studies of Self-Diffusion in Lipid Membranes on the Nanoscale

(2008) Konstantin Ulrich et al.   LANGMUIR

All-trans-retinoic acid stimulates translation and induces spine formation in hippocampal neurons through a membrane-associated RARα

(2007) Na Chen et al.   FASEB JOURNAL