Frequency-dependent exacerbation of Alzheimer’s disease neuropathophysiology

An acute functional screen identifies an effective antibody targeting amyloid-β oligomers based on calcium imaging

(2018) Xueying Wang et al.   Scientific Reports

Novel botanical drug DA-9803 prevents deficits in Alzheimer’s mouse models

(2018) Guillaume J. Pagnier et al.   Alzheimers Research & Therapy

Soluble oligomeric amyloid-β induces calcium dyshomeostasis that precedes synapse loss in the living mouse brain

(2017) Michal Arbel-Ornath et al.   Molecular Neurodegeneration

Optogenetic Restoration of Disrupted Slow Oscillations Halts Amyloid Deposition and Restores Calcium Homeostasis in an Animal Model of Alzheimer’s Disease

(2017) Ksenia V. Kastanenka et al.   PLoS One

Immunotherapy with Aducanumab Restores Calcium Homeostasis in Tg2576 Mice

(2016) Ksenia V. Kastanenka et al.   JOURNAL OF NEUROSCIENCE

Gamma frequency entrainment attenuates amyloid load and modifies microglia

(2016) Hannah F. Iaccarino et al.   NATURE

Rescue of long-range circuit dysfunction in Alzheimer's disease models

(2015) Marc Aurel Busche et al.   NATURE NEUROSCIENCE

Chronic Optogenetic Activation Augments Aβ Pathology in a Mouse Model of Alzheimer Disease

(2015) Kaoru Yamamoto et al.   Cell Reports

Two Phase 3 Trials of Bapineuzumab in Mild-to-Moderate Alzheimer's Disease

(2014) Stephen Salloway et al.   NEW ENGLAND JOURNAL OF MEDICINE

Phase 3 Trials of Solanezumab for Mild-to-Moderate Alzheimer's Disease

(2014) Rachelle S. Doody et al.   NEW ENGLAND JOURNAL OF MEDICINE

Inhibitory Interneuron Deficit Links Altered Network Activity and Cognitive Dysfunction in Alzheimer Model

(2012) Laure Verret et al.   CELL

Interneuron-mediated inhibition synchronizes neuronal activity during slow oscillation

(2012) Jen-Yung Chen et al.   JOURNAL OF PHYSIOLOGY-LONDON

Concurrent Impairments in Sleep and Memory in Amnestic Mild Cognitive Impairment

(2012) Carmen E. Westerberg et al.   JOURNAL OF THE INTERNATIONAL NEUROPSYCHOLOGICAL SOCIETY

Disruption of the Sleep-Wake Cycle and Diurnal Fluctuation of  -Amyloid in Mice with Alzheimer's Disease Pathology

(2012) J. H. Roh et al.   Science Translational Medicine

Slow and fast rhythms generated in the cerebral cortex of the anesthetized mouse

(2011) Marcel Ruiz-Mejias et al.   JOURNAL OF NEUROPHYSIOLOGY

Novel microdialysis method to assess neuropeptides and large molecules in free-moving mouse

(2011) S. Takeda et al.   NEUROSCIENCE

Spines, Plasticity, and Cognition in Alzheimer's Model Mice

(2011) Tara Spires-Jones et al.   NEURAL PLASTICITY

Mirrored Bilateral Slow-Wave Cortical Activity within Local Circuits Revealed by Fast Bihemispheric Voltage-Sensitive Dye Imaging in Anesthetized and Awake Mice

(2010) M. H. Mohajerani et al.   JOURNAL OF NEUROSCIENCE

Amyloid-β–induced neuronal dysfunction in Alzheimer's disease: from synapses toward neural networks

(2010) Jorge J Palop et al.   NATURE NEUROSCIENCE

Calcium Signalling and Alzheimer’s Disease

(2010) Michael J. Berridge   NEUROCHEMICAL RESEARCH

Alzheimer’s Disease and Neuronal Network Activity

(2009) Marc Gleichmann et al.   NEUROMOLECULAR MEDICINE

Memory loss in Alzheimer’s disease: implications for development of therapeutics

(2008) Carl A Gold et al.   Expert Review of Neurotherapeutics

Endocytosis Is Required for Synaptic Activity-Dependent Release of Amyloid-β In Vivo

(2008) John R. Cirrito et al.   NEURON

Aβ Plaques Lead to Aberrant Regulation of Calcium Homeostasis In Vivo Resulting in Structural and Functional Disruption of Neuronal Networks

(2008) Kishore V. Kuchibhotla et al.   NEURON