A sensitive and simple targeted proteomics approach to quantify transcription factor and membrane proteins of the unfolded protein response pathway in glioblastoma cells

Nano-LC/NSI MS Refines Lipidomics by Enhancing Lipid Coverage, Measurement Sensitivity, and Linear Dynamic Range

(2018) Niklas Danne-Rasche et al.   ANALYTICAL CHEMISTRY

Identification of key lipids critical for platelet activation by comprehensive analysis of the platelet lipidome

(2018) Bing Peng et al.   BLOOD

rawDiag - an R package supporting rational LC-MS method optimization for bottom-up proteomics

(2018) Christian Trachsel et al.   JOURNAL OF PROTEOME RESEARCH

Peptide Level Turnover Measurements Enable the Study of Proteoform Dynamics

(2018) Jana Zecha et al.   MOLECULAR & CELLULAR PROTEOMICS

Interactome Screening Identifies the ER Luminal Chaperone Hsp47 as a Regulator of the Unfolded Protein Response Transducer IRE1α

(2018) Denisse Sepulveda et al.   MOLECULAR CELL

The Unfolded Protein Response and Cell Fate Control

(2018) Claudio Hetz et al.   MOLECULAR CELL

The unfolded protein response regulator ATF6 promotes mesodermal differentiation

(2018) Heike Kroeger et al.   Science Signaling

Targeting multidrug-resistant ovarian cancer through estrogen receptor α dependent ATP depletion caused by hyperactivation of the unfolded protein response

(2018) Xiaobin Zheng et al.   Oncotarget

The unfolded protein response regulator ATF6 promotes mesodermal differentiation

(2018) Heike Kroeger et al.   Science Signaling

Transcription factor proteomics-Tools, applications, and challenges

(2017) Jovan Simicevic et al.   PROTEOMICS

PDI is an essential redox-sensitive activator of PERK during the unfolded protein response (UPR)

(2017) Philip Kranz et al.   Cell Death & Disease

Endoplasmic reticulum stress signaling and chemotherapy resistance in solid cancers

(2017) T Avril et al.   Oncogenesis

The unfolded protein response impacts melanoma progression by enhancing FGF expression and can be antagonized by a chemical chaperone

(2017) Karin Eigner et al.   Scientific Reports

Proteome Profiling and Ultrastructural Characterization of the Human RCMH Cell Line: Myoblastic Properties and Suitability for Myopathological Studies

(2016) Laxmikanth Kollipara et al.   JOURNAL OF PROTEOME RESEARCH

Proteomic Analysis Reveals Branch-specific Regulation of the Unfolded Protein Response by Nonsense-mediated mRNA Decay

(2016) Jana Sieber et al.   MOLECULAR & CELLULAR PROTEOMICS

Parallel reaction monitoring using quadrupole-Orbitrap mass spectrometer: Principle and applications

(2016) Adele Bourmaud et al.   PROTEOMICS

Bortezomib-resistance is associated with increased levels of proteasome subunits and apoptosis-avoidance

(2016) Yi-Xin Wu et al.   Oncotarget

Inhibition of IRE1α-driven pro-survival pathways is a promising therapeutic application in acute myeloid leukemia

(2016) Haibo Sun et al.   Oncotarget

Novel mechanism of enhancing IRE1α-XBP1 signalling via the PERK-ATF4 pathway

(2016) Akio Tsuru et al.   Scientific Reports

Cellular Signature of SIL1 Depletion: Disease Pathogenesis due to Alterations in Protein Composition Beyond the ER Machinery

(2015) Andreas Roos et al.   MOLECULAR NEUROBIOLOGY

An effective plasma membrane proteomics approach for small tissue samples

(2015) Katrien Smolders et al.   Scientific Reports

Conserved Peptide Fragmentation as a Benchmarking Tool for Mass Spectrometers and a Discriminating Feature for Targeted Proteomics

(2014) Umut H. Toprak et al.   MOLECULAR & CELLULAR PROTEOMICS

Anticipatory estrogen activation of the unfolded protein response is linked to cell proliferation and poor survival in estrogen receptor α-positive breast cancer

(2014) N Andruska et al.   ONCOGENE

Controlling low rates of cell differentiation through noise and ultrahigh feedback

(2014) R. Ahrends et al.   SCIENCE

Gli Protein Activity Is Controlled by Multisite Phosphorylation in Vertebrate Hedgehog Signaling

(2014) Pawel Niewiadomski et al.   Cell Reports

De-Differentiation Confers Multidrug Resistance Via Noncanonical PERK-Nrf2 Signaling

(2014) Catherine A. Del Vecchio et al.   PLOS BIOLOGY

ER-stress-induced transcriptional regulation increases protein synthesis leading to cell death

(2013) Jaeseok Han et al.   NATURE CELL BIOLOGY

Absolute quantification of transcription factors during cellular differentiation using multiplexed targeted proteomics

(2013) Jovan Simicevic et al.   NATURE METHODS

Protein Folding in the Endoplasmic Reticulum

(2013) I. Braakman et al.   Cold Spring Harbor Perspectives in Biology

Endoplasmic Reticulum Stress Sensing in the Unfolded Protein Response

(2013) B. M. Gardner et al.   Cold Spring Harbor Perspectives in Biology

Comparative Proteomic Analysis of Eleven Common Cell Lines Reveals Ubiquitous but Varying Expression of Most Proteins

(2012) Tamar Geiger et al.   MOLECULAR & CELLULAR PROTEOMICS

Parallel Reaction Monitoring for High Resolution and High Mass Accuracy Quantitative, Targeted Proteomics

(2012) Amelia C. Peterson et al.   MOLECULAR & CELLULAR PROTEOMICS

Bortezomib as the First Proteasome Inhibitor Anticancer Drug: Current Status and Future Perspectives

(2011) D. Chen et al.   CURRENT CANCER DRUG TARGETS

Systematic and quantitative comparison of digest efficiency and specificity reveals the impact of trypsin quality on MS-based proteomics

(2011) Julia Maria Burkhart et al.   Journal of Proteomics

Parallel adaptive feedback enhances reliability of the Ca2+ signaling system

(2011) E. Abell et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Skyline: an open source document editor for creating and analyzing targeted proteomics experiments

(2010) Brendan MacLean et al.   BIOINFORMATICS

Methods for proteomic analysis of transcription factors

(2009) Daifeng Jiang et al.   JOURNAL OF CHROMATOGRAPHY A

A census of human transcription factors: function, expression and evolution

(2009) Juan M. Vaquerizas et al.   NATURE REVIEWS GENETICS

Bortezomib inhibits tumor adaptation to hypoxia by stimulating the FIH-mediated repression of hypoxia-inducible factor-1

(2008) D. H. Shin et al.   BLOOD

Selected reaction monitoring for quantitative proteomics: a tutorial

(2008) Vinzenz Lange et al.   Molecular Systems Biology