The Small GTPase Rac1 Increases Cell Surface Stiffness and Enhances 3D Migration Into Extracellular Matrices
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Title
The Small GTPase Rac1 Increases Cell Surface Stiffness and Enhances 3D Migration Into Extracellular Matrices
Authors
Keywords
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Journal
Scientific Reports
Volume 9, Issue 1, Pages -
Publisher
Springer Science and Business Media LLC
Online
2019-05-22
DOI
10.1038/s41598-019-43975-0
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Note: Only part of the references are listed.- Rac1 modulates G-protein-coupled receptor-induced bronchial smooth muscle contraction
- (2018) Hiroyasu Sakai et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Tumor Cell Invadopodia: Invasive Protrusions that Orchestrate Metastasis
- (2017) Robert J. Eddy et al. TRENDS IN CELL BIOLOGY
- Focal adhesion kinase activity is required for actomyosin contractility-based invasion of cells into dense 3D matrices
- (2017) Claudia T. Mierke et al. Scientific Reports
- Biphasic response of cell invasion to matrix stiffness in three-dimensional biopolymer networks
- (2015) Nadine R. Lang et al. Acta Biomaterialia
- The phenotype of cancer cell invasion controlled by fibril diameter and pore size of 3D collagen networks
- (2015) Jiranuwat Sapudom et al. BIOMATERIALS
- Rho GTPase signalling in cell migration
- (2015) Anne J Ridley CURRENT OPINION IN CELL BIOLOGY
- Fibroblasts Lead the Way: A Unified View of 3D Cell Motility
- (2015) Ryan J. Petrie et al. TRENDS IN CELL BIOLOGY
- Ena/VASP Proteins Cooperate with the WAVE Complex to Regulate the Actin Cytoskeleton
- (2014) Xing Judy Chen et al. DEVELOPMENTAL CELL
- Requirements for and consequences of Rac-dependent protrusion
- (2014) Anika Steffen et al. EUROPEAN JOURNAL OF CELL BIOLOGY
- A Novel Interaction between the SH2 Domain of Signaling Adaptor Protein Nck-1 and the Upstream Regulator of the Rho Family GTPase Rac1 Engulfment and Cell Motility 1 (ELMO1) Promotes Rac1 Activation and Cell Motility
- (2014) Guo Zhang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- A Trio–Rac1–Pak1 signalling axis drives invadopodia disassembly
- (2014) Yasmin Moshfegh et al. NATURE CELL BIOLOGY
- Rac1-Dependent Lamellipodial Motility in Prostate Cancer PC-3 Cells Revealed by Optogenetic Control of Rac1 Activity
- (2014) Takuma Kato et al. PLoS One
- The fundamental role of mechanical properties in the progression of cancer disease and inflammation
- (2014) Claudia Tanja Mierke REPORTS ON PROGRESS IN PHYSICS
- The Rac-FRET Mouse Reveals Tight Spatiotemporal Control of Rac Activity in Primary Cells and Tissues
- (2014) Anna-Karin E. Johnsson et al. Cell Reports
- Phagocytized Beads Reduce the α5β1 Integrin Facilitated Invasiveness of Cancer Cells by Regulating Cellular Stiffness
- (2013) Claudia T. Mierke CELL BIOCHEMISTRY AND BIOPHYSICS
- Physical limits of cell migration: Control by ECM space and nuclear deformation and tuning by proteolysis and traction force
- (2013) Katarina Wolf et al. JOURNAL OF CELL BIOLOGY
- Rac function is crucial for cell migration but is not required for spreading and focal adhesion formation
- (2013) A. Steffen et al. JOURNAL OF CELL SCIENCE
- The small GTPase Rac1 is required for smooth muscle contraction
- (2013) Awahan Rahman et al. JOURNAL OF PHYSIOLOGY-LONDON
- Functions of cofilin in cell locomotion and invasion
- (2013) Jose Javier Bravo-Cordero et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- The integrin alphav beta3 increases cellular stiffness and cytoskeletal remodeling dynamics to facilitate cancer cell invasion
- (2013) Claudia Tanja Mierke NEW JOURNAL OF PHYSICS
- Evaluation of single-cell biomechanics as potential marker for oral squamous cell carcinomas: a pilot study
- (2013) J Runge et al. ORAL DISEASES
- Interactions between the discoidin domain receptor 1 and 1 integrin regulate attachment to collagen
- (2013) L. A. Staudinger et al. Biology Open
- Arp2/3 Is Critical for Lamellipodia and Response to Extracellular Matrix Cues but Is Dispensable for Chemotaxis
- (2012) Congying Wu et al. CELL
- The Arp2/3 complex is required for lamellipodia extension and directional fibroblast cell migration
- (2012) Praveen Suraneni et al. JOURNAL OF CELL BIOLOGY
- Actin branching in the initiation and maintenance of lamellipodia
- (2012) M. Vinzenz et al. JOURNAL OF CELL SCIENCE
- Mechanics: The forces of cancer
- (2012) Erika Jonietz NATURE
- Cell Visco-Elasticity Measured with AFM and Optical Trapping at Sub-Micrometer Deformations
- (2012) Schanila Nawaz et al. PLoS One
- Life at the Leading Edge
- (2011) Anne J. Ridley CELL
- Activation of a RhoA/Myosin II-Dependent but Arp2/3 Complex-Independent Pathway Facilitates Salmonella Invasion
- (2011) Jan Hänisch et al. Cell Host & Microbe
- Rac1 Drives Melanoblast Organization during Mouse Development by Orchestrating Pseudopod- Driven Motility and Cell-Cycle Progression
- (2011) Ang Li et al. DEVELOPMENTAL CELL
- Contractile Forces Contribute to Increased Glycosylphosphatidylinositol-anchored Receptor CD24-facilitated Cancer Cell Invasion
- (2011) Claudia Tanja Mierke et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Cancer Cells Regulate Biomechanical Properties of Human Microvascular Endothelial Cells
- (2011) Claudia Tanja Mierke JOURNAL OF BIOLOGICAL CHEMISTRY
- Integrin 5 1 facilitates cancer cell invasion through enhanced contractile forces
- (2011) C. T. Mierke et al. JOURNAL OF CELL SCIENCE
- Visualizing branched actin filaments in lamellipodia by electron tomography
- (2011) Changsong Yang et al. NATURE CELL BIOLOGY
- Generation of branched actin networks: assembly and regulation of the N-WASP and WAVE molecular machines
- (2010) Emmanuel Derivery et al. BIOESSAYS
- Mechanisms of force generation and force transmission during interstitial leukocyte migration
- (2010) Jörg Renkawitz et al. EMBO REPORTS
- Determinants of leader cells in collective cell migration
- (2010) Antoine A. Khalil et al. Integrative Biology
- Vinculin Facilitates Cell Invasion into Three-dimensional Collagen Matrices
- (2010) Claudia T. Mierke et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Structure and control of the actin regulatory WAVE complex
- (2010) Zhucheng Chen et al. NATURE
- Oral Cancer Diagnosis by Mechanical Phenotyping
- (2009) T. W. Remmerbach et al. CANCER RESEARCH
- Interstitial cell migration: integrin-dependent and alternative adhesion mechanisms
- (2009) Samuel Schmidt et al. CELL AND TISSUE RESEARCH
- Invadosomes at a glance
- (2009) S. Linder JOURNAL OF CELL SCIENCE
- Activation of the WAVE Complex by Coincident Signals Controls Actin Assembly
- (2009) Andres M. Lebensohn et al. MOLECULAR CELL
- The WAVE regulatory complex is inhibited
- (2009) Ayman M Ismail et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- The regulatory role of cell mechanics for migration of differentiating myeloid cells
- (2009) F. Lautenschlager et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Integrin Clustering Is Driven by Mechanical Resistance from the Glycocalyx and the Substrate
- (2009) Matthew J. Paszek et al. PLoS Computational Biology
- Mapping proteolytic cancer cell-extracellular matrix interfaces
- (2008) Katarina Wolf et al. CLINICAL & EXPERIMENTAL METASTASIS
- Arp2/3 complex interactions and actin network turnover in lamellipodia
- (2008) Frank PL Lai et al. EMBO JOURNAL
- On the Rho'd: The regulation of membrane protrusions by Rho-GTPases
- (2008) Markus Ladwein et al. FEBS LETTERS
- Interstitial leukocyte migration and immune function
- (2008) Peter Friedl et al. NATURE IMMUNOLOGY
- Mammalian Rho GTPases: new insights into their functions from in vivo studies
- (2008) Sarah J. Heasman et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Mechano-Coupling and Regulation of Contractility by the Vinculin Tail Domain
- (2007) Claudia Tanja Mierke et al. BIOPHYSICAL JOURNAL
- Breakdown of the Endothelial Barrier Function in Tumor Cell Transmigration
- (2007) Claudia Tanja Mierke et al. BIOPHYSICAL JOURNAL
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