A Multi-Trait Approach Identified Genetic Variants Including a Rare Mutation in RGS3 with Impact on Abnormalities of Cardiac Structure/Function

Integration of genomics and metabolomics for prioritization of rare disease variants: a 2018 literature review

(2018) Emma Graham et al.   JOURNAL OF INHERITED METABOLIC DISEASE

Whole-exome sequencing identifies common and rare variant metabolic QTLs in a Middle Eastern population

(2018) Noha A. Yousri et al.   Nature Communications

GWAS of the electrocardiographic QT interval in Hispanics/Latinos generalizes previously identified loci and identifies population-specific signals

(2017) Raúl Méndez-Giráldez et al.   Scientific Reports

Gene- and pathway-based association tests for multiple traits with GWAS summary statistics

(2016) Il-Youp Kwak et al.   BIOINFORMATICS

Identification of Rare Variants in Metabolites of the Carnitine Pathway by Whole Genome Sequencing Analysis

(2016) Akram Yazdani et al.   GENETIC EPIDEMIOLOGY

Statistical Methods for Testing Genetic Pleiotropy

(2016) D. J. Schaid et al.   GENETICS

Generating a robust statistical causal structure over 13 cardiovascular disease risk factors using genomics data

(2016) Azam Yazdani et al.   JOURNAL OF BIOMEDICAL INFORMATICS

52 Genetic Loci Influencing Myocardial Mass

(2016) Pim van der Harst et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Rare variants analysis using penalization methods for whole genome sequence data

(2015) Akram Yazdani et al.   BMC BIOINFORMATICS

Discrete optimal Bayesian classification with error-conditioned sequential sampling

(2015) Ariana Broumand et al.   PATTERN RECOGNITION

Launching genomics into the cloud: deployment of Mercury, a next generation sequence analysis pipeline

(2014) Jeffrey G Reid et al.   BMC BIOINFORMATICS

MCMC implementation of the optimal Bayesian classifier for non-Gaussian models: model-based RNA-Seq classification

(2014) Jason M Knight et al.   BMC BIOINFORMATICS

Genome-Wide Meta-Analyses of Plasma Renin Activity and Concentration Reveal Association With the Kininogen 1 and Prekallikrein GenesCLINICAL PERSPECTIVE

(2014) Wolfgang Lieb et al.   Circulation-Cardiovascular Genetics

A Comparison of Multivariate Genome-Wide Association Methods

(2014) Tessel E. Galesloot et al.   PLoS One

Rationale and Design of a Multicenter Echocardiographic Study to Assess the Relationship Between Cardiac Structure and Function and Heart Failure Risk in a Biracial Cohort of Community-Dwelling Elderly Persons

(2013) Amil M. Shah et al.   Circulation-Cardiovascular Imaging

Regulator of G Protein Signaling 3 Protects Against Cardiac Hypertrophy in Mice

(2013) Yu Liu et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

N-Acetylcysteine Effects on Transforming Growth Factor-β and Tumor Necrosis Factor-α Serum Levels as Pro-Fibrotic and Inflammatory Biomarkers in Patients Following ST-Segment Elevation Myocardial Infarction

(2013) Azita Hajhossein Talasaz et al.   Drugs in research & development

Estimation of pleiotropy between complex diseases using single-nucleotide polymorphism-derived genomic relationships and restricted maximum likelihood

(2012) S.H. Lee et al.   BIOINFORMATICS

A mixed-model approach for genome-wide association studies of correlated traits in structured populations

(2012) Arthur Korte et al.   NATURE GENETICS

Regulators of G-Protein Signaling in the Heart and Their Potential as Therapeutic Targets

(2011) Peng Zhang et al.   CIRCULATION RESEARCH

Exome sequencing identifies MRPL3 mutation in mitochondrial cardiomyopathy

(2011) Louise Galmiche et al.   HUMAN MUTATION

9p21 DNA variants associated with coronary artery disease impair interferon-γ signalling response

(2011) Olivier Harismendy et al.   NATURE

Transforming growth factor (TGF)-β signaling in cardiac remodeling

(2010) Marcin Dobaczewski et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

The Genetics of Congestive Heart Failure

(2010) Calum A. MacRae   Heart Failure Clinics

Inhibition of transforming growth factor-β signaling induces left ventricular dilation and dysfunction in the pressure-overloaded heart

(2009) Jason A. Lucas et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

A genetic variant on chromosome 9p21 and incident heart failure in the ARIC study

(2009) K. Yamagishi et al.   EUROPEAN HEART JOURNAL

Genetic Variants Associated With Cardiac Structure and Function

(2009) Ramachandran S. Vasan et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION