The nuclear interactome of DYRK1A reveals a functional role in DNA damage repair
Published 2019 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
The nuclear interactome of DYRK1A reveals a functional role in DNA damage repair
Authors
Keywords
-
Journal
Scientific Reports
Volume 9, Issue 1, Pages -
Publisher
Springer Nature
Online
2019-04-25
DOI
10.1038/s41598-019-42990-5
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- LncRNA OIP5-AS1 regulates radioresistance by targeting DYRK1A through miR-369-3p in colorectal cancer cells
- (2018) Yanmei Zou et al. EUROPEAN JOURNAL OF CELL BIOLOGY
- Massive mining of publicly available RNA-seq data from human and mouse
- (2018) Alexander Lachmann et al. Nature Communications
- Functional characterization of DYRK1A missense variants associated with a syndromic form of intellectual deficiency and autism
- (2018) Esti Wahyu Widowati et al. Biology Open
- Phase-separation mechanism for C-terminal hyperphosphorylation of RNA polymerase II
- (2018) Huasong Lu et al. NATURE
- RNF169 limits 53BP1 deposition at DSBs to stimulate single-strand annealing repair
- (2018) Liwei An et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Determining consistent prognostic biomarkers of overall survival and vascular invasion in hepatocellular carcinoma
- (2018) Otília Menyhárt et al. Royal Society Open Science
- Haploinsufficiency of the E3 ubiquitin-protein ligase gene TRIP12 causes intellectual disability with or without autism spectrum disorders, speech delay, and dysmorphic features
- (2017) Jing Zhang et al. HUMAN GENETICS
- Architecture of the human interactome defines protein communities and disease networks
- (2017) Edward L. Huttlin et al. NATURE
- Dual-utility NLS drives RNF169-dependent DNA damage responses
- (2017) Liwei An et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Dosage sensitivity is a major determinant of human copy number variant pathogenicity
- (2017) Alan M. Rice et al. Nature Communications
- The anaphase promoting complex impacts repair choice by protecting ubiquitin signalling at DNA damage sites
- (2017) Kyungsoo Ha et al. Nature Communications
- miRpower: a web-tool to validate survival-associated miRNAs utilizing expression data from 2178 breast cancer patients
- (2016) András Lánczky et al. BREAST CANCER RESEARCH AND TREATMENT
- Structure of BRCA1-BRCT/Abraxas Complex Reveals Phosphorylation-Dependent BRCT Dimerization at DNA Damage Sites
- (2016) Qian Wu et al. MOLECULAR CELL
- The structural basis of modified nucleosome recognition by 53BP1
- (2016) Marcus D. Wilson et al. NATURE
- Down syndrome and the complexity of genome dosage imbalance
- (2016) Stylianos E. Antonarakis NATURE REVIEWS GENETICS
- Enrichr: a comprehensive gene set enrichment analysis web server 2016 update
- (2016) Maxim V. Kuleshov et al. NUCLEIC ACIDS RESEARCH
- Unreplicated DNA remaining from unperturbed S phases passes through mitosis for resolution in daughter cells
- (2016) Alberto Moreno et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Structural Basis for the Non-catalytic Functions of Protein Kinases
- (2016) Jennifer E. Kung et al. STRUCTURE
- Three-Dimensional Architecture of the Human BRCA1-A Histone Deubiquitinase Core Complex
- (2016) Otto J.P. Kyrieleis et al. Cell Reports
- A Human Interactome in Three Quantitative Dimensions Organized by Stoichiometries and Abundances
- (2015) Marco Y. Hein et al. CELL
- The BioPlex Network: A Systematic Exploration of the Human Interactome
- (2015) Edward L. Huttlin et al. CELL
- Ten new cases further delineate the syndromic intellectual disability phenotype caused by mutations in DYRK1A
- (2015) Lucas M Bronicki et al. EUROPEAN JOURNAL OF HUMAN GENETICS
- Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes
- (2015) Jean-Philippe Lambert et al. Journal of Proteomics
- Chromatin-wide Profiling of DYRK1A Reveals a Role as a Gene-Specific RNA Polymerase II CTD Kinase
- (2015) Chiara Di Vona et al. MOLECULAR CELL
- Disruptive de novo mutations of DYRK1A lead to a syndromic form of autism and ID
- (2015) B W M van Bon et al. MOLECULAR PSYCHIATRY
- Atomic structure of the APC/C and its mechanism of protein ubiquitination
- (2015) Leifu Chang et al. NATURE
- The Focinator - a new open-source tool for high-throughput foci evaluation of DNA damage
- (2015) Sebastian Oeck et al. Radiation Oncology
- Identification of Human Neuronal Protein Complexes Reveals Biochemical Activities and Convergent Mechanisms of Action in Autism Spectrum Disorders
- (2015) Jingjing Li et al. Cell Systems
- DYRK1A-mediated Cyclin D1 Degradation in Neural Stem Cells Contributes to the Neurogenic Cortical Defects in Down Syndrome
- (2015) Sònia Najas et al. EBioMedicine
- Selectivity Profiling and Biological Activity of Novel β-Carbolines as Potent and Selective DYRK1 Kinase Inhibitors
- (2015) Katharina Rüben et al. PLoS One
- Cancer stem cells and radioresistance
- (2014) Kiera Rycaj et al. INTERNATIONAL JOURNAL OF RADIATION BIOLOGY
- Regulation of 53BP1 Protein Stability by RNF8 and RNF168 Is Important for Efficient DNA Double-Strand Break Repair
- (2014) Yiheng Hu et al. PLoS One
- Dissecting the cell to nucleus, perinucleus and cytosol
- (2014) Tattym E. Shaiken et al. Scientific Reports
- Novel Parallelized Quadrupole/Linear Ion Trap/Orbitrap Tribrid Mass Spectrometer Improving Proteome Coverage and Peptide Identification Rates
- (2013) Michael W. Senko et al. ANALYTICAL CHEMISTRY
- 53BP1 is a reader of the DNA-damage-induced H2A Lys 15 ubiquitin mark
- (2013) Amélie Fradet-Turcotte et al. NATURE
- The transience of transient overexpression
- (2013) Toby J Gibson et al. NATURE METHODS
- The CRAPome: a contaminant repository for affinity purification–mass spectrometry data
- (2013) Dattatreya Mellacheruvu et al. NATURE METHODS
- The Protein Interaction Landscape of the Human CMGC Kinase Group
- (2013) Markku Varjosalo et al. Cell Reports
- Dual-specificity Tyrosine Phosphorylation-regulated Kinase 1A (Dyrk1A) Modulates Serine/Arginine-rich Protein 55 (SRp55)-promoted Tau Exon 10 Inclusion
- (2012) Xiaomin Yin et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Human RNF169 is a negative regulator of the ubiquitin-dependent response to DNA double-strand breaks
- (2012) Maria Poulsen et al. JOURNAL OF CELL BIOLOGY
- BRCA1-associated exclusion of 53BP1 from DNA damage sites underlies temporal control of DNA repair
- (2012) J. R. Chapman et al. JOURNAL OF CELL SCIENCE
- DYRK1A in Down syndrome: an oncogene or tumor suppressor?
- (2012) Yehudit Birger et al. JOURNAL OF CLINICAL INVESTIGATION
- Increased dosage of the chromosome 21 ortholog Dyrk1a promotes megakaryoblastic leukemia in a murine model of Down syndrome
- (2012) Sébastien Malinge et al. JOURNAL OF CLINICAL INVESTIGATION
- Selectivity, Cocrystal Structures, and Neuroprotective Properties of Leucettines, a Family of Protein Kinase Inhibitors Derived from the Marine Sponge Alkaloid Leucettamine B
- (2012) Tania Tahtouh et al. JOURNAL OF MEDICINAL CHEMISTRY
- Quantitative Live Cell Imaging Reveals a Gradual Shift between DNA Repair Mechanisms and a Maximal Use of HR in Mid S Phase
- (2012) Ketki Karanam et al. MOLECULAR CELL
- DYRK1A binds to an evolutionarily conserved WD40-repeat protein WDR68 and induces its nuclear translocation
- (2011) Yoshihiko Miyata et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Transient expression of Mnb/Dyrk1a couples cell cycle exit and differentiation of neuronal precursors by inducing p27KIP1 expression and suppressing NOTCH signaling
- (2011) B. Hammerle et al. DEVELOPMENT
- DYRK1A protein kinase promotes quiescence and senescence through DREAM complex assembly
- (2011) L. Litovchick et al. GENES & DEVELOPMENT
- DYRK family of protein kinases: evolutionary relationships, biochemical properties, and functional roles
- (2010) Sergi Aranda et al. FASEB JOURNAL
- Cognitive deficits and associated neurological complications in individuals with Down's syndrome
- (2010) Ira T Lott et al. LANCET NEUROLOGY
- Development of a novel selective inhibitor of the Down syndrome-related kinase Dyrk1A
- (2010) Yasushi Ogawa et al. Nature Communications
- ClueGO: a Cytoscape plug-in to decipher functionally grouped gene ontology and pathway annotation networks
- (2009) Gabriela Bindea et al. BIOINFORMATICS
- Harmine specifically inhibits protein kinase DYRK1A and interferes with neurite formation
- (2009) Nora Göckler et al. FEBS Journal
- NBA1, a new player in the Brca1 A complex, is required for DNA damage resistance and checkpoint control
- (2009) B. Wang et al. GENES & DEVELOPMENT
- DYRK1A interacts with the REST/NRSF-SWI/SNF chromatin remodelling complex to deregulate gene clusters involved in the neuronal phenotypic traits of Down syndrome
- (2009) Aude-Marie Lepagnol-Bestel et al. HUMAN MOLECULAR GENETICS
- Combination of FASP and StageTip-Based Fractionation Allows In-Depth Analysis of the Hippocampal Membrane Proteome
- (2009) Jacek R. Wiśniewski et al. JOURNAL OF PROTEOME RESEARCH
- Genome-Wide Analysis of Histidine Repeats Reveals Their Role in the Localization of Human Proteins to the Nuclear Speckles Compartment
- (2009) Eulàlia Salichs et al. PLoS Genetics
- The role of overexpressed DYRK1A protein in the early onset of neurofibrillary degeneration in Down syndrome
- (2008) Jerzy Wegiel et al. ACTA NEUROPATHOLOGICA
- DYRK1A-Dosage Imbalance Perturbs NRSF/REST Levels, Deregulating Pluripotency and Embryonic Stem Cell Fate in Down Syndrome
- (2008) Claudia Canzonetta et al. AMERICAN JOURNAL OF HUMAN GENETICS
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now