Mesenchymal stem cell-based bioengineered constructs: foreign body response, cross-talk with macrophages and impact of biomaterial design strategies for pelvic floor disorders

Prolapse surgery versus vaginal pessary in women with symptomatic pelvic organ prolapse: which factors influence the choice of treatment?

(2019) Barbara Bodner-Adler et al.   ARCHIVES OF GYNECOLOGY AND OBSTETRICS

Demonstration of improved tissue integration and angiogenesis with an elastic, estradiol releasing polyurethane material designed for use in pelvic floor repair

(2018) Sarah Shafaat et al.   NEUROUROLOGY AND URODYNAMICS

Implant Porosity and the Foreign Body Response

(2018) Sumanas W. Jordan et al.   PLASTIC AND RECONSTRUCTIVE SURGERY

Mesenchymal-myeloid interaction in the regulation of immunity

(2018) Tik Shing Cheung et al.   SEMINARS IN IMMUNOLOGY

In Vivo Survival of Human Endometrial Mesenchymal Stem Cells Transplanted Under the Kidney Capsule of Immunocompromised Mice

(2018) Shanti Gurung et al.   STEM CELLS AND DEVELOPMENT

Stem Cells for Urinary Incontinence: Functional Differentiation or Cytokine Effects?

(2018) Bradley C. Gill et al.   UROLOGY

Endometrial Mesenchymal Stem/Stromal Cells Modulate the Macrophage Response to Implanted Polyamide/Gelatin Composite Mesh in Immunocompromised and Immunocompetent Mice

(2018) S. Darzi et al.   Scientific Reports

Curcumin-mediated bone marrow mesenchymal stem cell sheets create a favorable immune microenvironment for adult full-thickness cutaneous wound healing

(2018) Zhi Yang et al.   Stem Cell Research & Therapy

Adenosine Production by Biomaterial‐Supported Mesenchymal Stromal Cells Reduces the Innate Inflammatory Response in Myocardial Ischemia/Reperfusion Injury

(2018) Eric Y. Shin et al.   Journal of the American Heart Association

Blended Nanostructured Degradable Mesh with Endometrial Mesenchymal Stem Cells Promotes Tissue Integration and Anti-Inflammatory Response in Vivo for Pelvic Floor Application

(2018) Shayanti Mukherjee et al.   BIOMACROMOLECULES

Minimal modulation of the host immune response to SIS matrix implants by mesenchymal stem cells from the amniotic fluid

(2017) F. Lesage et al.   Hernia

Risk factors for prolapse recurrence: systematic review and meta-analysis

(2017) Talia Friedman et al.   INTERNATIONAL UROGYNECOLOGY JOURNAL

Macrophage phenotype in response to ECM bioscaffolds

(2017) Luai Huleihel et al.   SEMINARS IN IMMUNOLOGY

Dendritic cells in host response to biologic scaffolds

(2017) Cynthia A. Leifer   SEMINARS IN IMMUNOLOGY

Mesenchymal Stem Cells: The Moniker Fits the Science

(2017) Siddaraju V. Boregowda et al.   STEM CELLS

ML290 is a biased allosteric agonist at the relaxin receptor RXFP1

(2017) Martina Kocan et al.   Scientific Reports

Trials of transvaginal mesh devices for pelvic organ prolapse: a systematic database review of the US FDA approval process

(2017) Carl J Heneghan et al.   BMJ Open

Drugs and Targets in Fibrosis

(2017) Xiaoyi Li et al.   Frontiers in Pharmacology

Ovine multiparity is associated with diminished vaginal muscularis, increased elastic fibres and vaginal wall weakness: implication for pelvic organ prolapse

(2017) Stuart Emmerson et al.   Scientific Reports

Tissue response to collagen containing polypropylene meshes in an ovine vaginal repair model

(2016) Saeedeh Darzi et al.   Acta Biomaterialia

Trends in internet search activity, media coverage, and patient-centered health information after the FDA safety communications on surgical mesh for pelvic organ prolapse

(2016) Benjamin V. Stone et al.   INTERNATIONAL UROGYNECOLOGY JOURNAL

Vaginal wall weakness in parous ewes: a potential preclinical model of pelvic organ prolapse

(2016) Natharnia Young et al.   INTERNATIONAL UROGYNECOLOGY JOURNAL

Female pelvic organ prolapse using pessaries: systematic review

(2016) Suelene Costa de Albuquerque Coelho et al.   INTERNATIONAL UROGYNECOLOGY JOURNAL

Pessary types and discontinuation rates in patients with advanced pelvic organ prolapse

(2016) Birte Wolff et al.   INTERNATIONAL UROGYNECOLOGY JOURNAL

Recruitment of mesenchymal stem cells and macrophages by dual release of stromal cell-derived factor-1 and a macrophage recruitment agent enhances wound closure

(2016) Yang-Hee Kim et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

The pathology of the foreign body reaction against biomaterials

(2016) R. Klopfleisch et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

The role of the local environment and epigenetics in shaping macrophage identity and their effect on tissue homeostasis

(2016) Ido Amit et al.   NATURE IMMUNOLOGY

Toward a new generation of pelvic floor implants with electrospun nanofibrous matrices: A feasibility study

(2016) Mahshid Vashaghian et al.   NEUROUROLOGY AND URODYNAMICS

Women's views on autologous cell-based therapy for post-obstetric incontinence

(2016) Bernice Wright et al.   Regenerative Medicine

Adipose Tissue-Derived Stem Cells in Regenerative Medicine

(2016) Laura Frese et al.   TRANSFUSION MEDICINE AND HEMOTHERAPY

Engineering Immunomodulatory Biomaterials To Tune the Inflammatory Response

(2016) Ajaykumar Vishwakarma et al.   TRENDS IN BIOTECHNOLOGY

Pelvic Organ Prolapse Surgery in Academic Female Pelvic Medicine and Reconstructive Surgery Urology Practice in the Setting of the Food and Drug Administration Public Health Notifications

(2016) Austin Younger et al.   UROLOGY

Identification and Characterization of Human Endometrial Mesenchymal Stem/Stromal Cells and Their Potential for Cellular Therapy

(2016) Saeedeh Darzi et al.   Stem Cells Translational Medicine

Bone Marrow Mesenchymal Stem Cell-Based Engineered Cartilage Ameliorates Polyglycolic Acid/Polylactic Acid Scaffold-Induced Inflammation Through M2 Polarization of Macrophages in a Pig Model

(2016) Jinping Ding et al.   Stem Cells Translational Medicine

Microscale Biomaterials with Bioinspired Complexity of Early Embryo Development and in the Ovary for Tissue Engineering and Regenerative Medicine

(2016) Xiaoming He   ACS Biomaterials-Science & Engineering

Microscale Biomaterials with Bioinspired Complexity of Early Embryo Development and in the Ovary for Tissue Engineering and Regenerative Medicine

(2016) Xiaoming He   ACS Biomaterials Science & Engineering

Endometrial mesenchymal stem cells as a cell based therapy for pelvic organ prolapse

(2016) Stuart J Emmerson et al.   World Journal of Stem Cells

Biodegradable chitosan microparticles induce delayed STAT-1 activation and lead to distinct cytokine responses in differentially polarized human macrophages in vitro

(2015) David Fong et al.   Acta Biomaterialia

Temporal changes in the biomechanical properties of endometrial mesenchymal stem cell seeded scaffolds in a rat model

(2015) S.L. Edwards et al.   Acta Biomaterialia

Characterization of the host inflammatory response following implantation of prolapse mesh in rhesus macaque

(2015) Bryan N. Brown et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Human mesenchymal stem cells - current trends and future prospective

(2015) Imran Ullah et al.   BIOSCIENCE REPORTS

Stem Cell Therapies in Clinical Trials: Progress and Challenges

(2015) Alan Trounson et al.   Cell Stem Cell

An integrative review and severity classification of complications related to pessary use in the treatment of female pelvic organ prolapse

(2015) Marwa Mohammed Abdulaziz et al.   CUAJ-Canadian Urological Association Journal

Epidemiological trends and future care needs for pelvic floor disorders

(2015) Alexis A. Dieter et al.   CURRENT OPINION IN OBSTETRICS & GYNECOLOGY

Tissue-resident macrophages: then and now

(2015) Luke C. Davies et al.   IMMUNOLOGY

Mesenchymal stromal cells and the innate immune response

(2015) Katarina Le Blanc et al.   IMMUNOLOGY LETTERS

Integration of nondegradable polystyrene and degradable gelatin in a core–sheath nanofibrous patch for pelvic reconstruction

(2015) Liangpeng Ge et al.   International Journal of Nanomedicine

Incorporation of Mg particles into PDLLA regulates mesenchymal stem cell and macrophage responses

(2015) Sandra C. Cifuentes et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Pore size and pore shape – but not mesh density – alter the mechanical strength of tissue ingrowth and host tissue response to synthetic mesh materials in a porcine model of ventral hernia repair

(2015) Spencer P. Lake et al.   Journal of the Mechanical Behavior of Biomedical Materials

Biomaterial based modulation of macrophage polarization: a review and suggested design principles

(2015) Rukmani Sridharan et al.   Materials Today

Inflammasomes: mechanism of action, role in disease and therapeutics

(2015) Haitao Guo et al.   NATURE MEDICINE

Macrophages, Foreign Body Giant Cells and Their Response to Implantable Biomaterials

(2015) Zeeshan Sheikh et al.   Materials

Inhibition of Transforming Growth Factor-β Receptor signaling promotes culture expansion of undifferentiated human Endometrial Mesenchymal Stem/stromal Cells

(2015) Shanti Gurung et al.   Scientific Reports

Immunoregulation by Mesenchymal Stem Cells: Biological Aspects and Clinical Applications

(2015) Marta E. Castro-Manrreza et al.   Journal of Immunology Research

Extracellular Matrix Reorganization During Wound Healing and Its Impact on Abnormal Scarring

(2015) Meilang Xue et al.   Advances in Wound Care

ECM hydrogel coating mitigates the chronic inflammatory response to polypropylene mesh

(2014) Denver M. Faulk et al.   BIOMATERIALS

Transcriptional switching in macrophages associated with the peritoneal foreign body response

(2014) Jane E Mooney et al.   IMMUNOLOGY AND CELL BIOLOGY

AcuteIn VivoResponse to an Alternative Implant for Urogynecology

(2014) Sabiniano Roman Regueros et al.   Biomed Research International

Molecular Mechanisms That Influence the Macrophage M1–M2 Polarization Balance

(2014) Nan Wang et al.   Frontiers in Immunology

Secretion of immunoregulatory cytokines by mesenchymal stem cells

(2014) Dobroslav Kyurkchiev   World Journal of Stem Cells

An update on the current and future demand for care of pelvic floor disorders in the United States

(2013) Anna C. Kirby et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Toward the use of endometrial and menstrual blood mesenchymal stem cells for cell-based therapies

(2013) Daniela Ulrich et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

Macrophage activation and skeletal muscle healing following traumatic injury

(2013) Margaret L Novak et al.   JOURNAL OF PATHOLOGY

Characterisation of clinical and newly fabricated meshes for pelvic organ prolapse repair

(2013) Sharon L. Edwards et al.   Journal of the Mechanical Behavior of Biomedical Materials

Individualised pelvic floor muscle training in women with pelvic organ prolapse (POPPY): a multicentre randomised controlled trial

(2013) Suzanne Hagen et al.   LANCET

Gold Nanoparticle Loaded Hybrid Nanofibers for Cardiogenic Differentiation of Stem Cells for Infarcted Myocardium Regeneration

(2013) Rajeswari Ravichandran et al.   MACROMOLECULAR BIOSCIENCE

Origin of monocytes and macrophages in a committed progenitor

(2013) Jan Hettinger et al.   NATURE IMMUNOLOGY

Anti-CD47 antibody-mediated phagocytosis of cancer by macrophages primes an effective antitumor T-cell response

(2013) D. Tseng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Comparison of Three Types of Stress Urinary Incontinence Rat Models: Electrocauterization, Pudendal Denervation, and Vaginal Distension

(2013) Sung-Hoo Hong et al.   UROLOGY

Expanded applications, shifting paradigms and an improved understanding of host–biomaterial interactions

(2012) Bryan N. Brown et al.   Acta Biomaterialia

Macrophage polarization: An opportunity for improved outcomes in biomaterials and regenerative medicine

(2012) Bryan N. Brown et al.   BIOMATERIALS

A Novel Marker of Human Endometrial Mesenchymal Stem-Like Cells

(2012) Hirotaka Masuda et al.   CELL TRANSPLANTATION

Fate Mapping Reveals Origins and Dynamics of Monocytes and Tissue Macrophages under Homeostasis

(2012) Simon Yona et al.   IMMUNITY

Student award winner in the undergraduate category for the society of biomaterials 9th World Biomaterials Congress, Chengdu, China, June 1-5, 2012

(2012) Anna K. Blakney et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Macrophage plasticity and polarization: in vivo veritas

(2012) Antonio Sica et al.   JOURNAL OF CLINICAL INVESTIGATION

A Preclinical Evaluation of Alternative Synthetic Biomaterials for Fascial Defect Repair Using a Rat Abdominal Hernia Model

(2012) Daniela Ulrich et al.   PLoS One

Relief from Within: A Peptide Therapy for Fibrosis

(2012) S. P. Atamas   Science Translational Medicine

A Peptide Derived from Endostatin Ameliorates Organ Fibrosis

(2012) Y. Yamaguchi et al.   Science Translational Medicine

Optimization and Scale-up Culture of Human Endometrial Multipotent Mesenchymal Stromal Cells: Potential for Clinical Application

(2012) Gayathri Rajaraman et al.   TISSUE ENGINEERING PART C-METHODS

Lack of TNF-α–Induced MMP-9 Production and Abnormal E-Cadherin Redistribution Associated with Compromised Fusion in MCP-1–Null Macrophages

(2011) Eleni A. Skokos et al.   AMERICAN JOURNAL OF PATHOLOGY

Immune responses to implants – A review of the implications for the design of immunomodulatory biomaterials

(2011) Sandra Franz et al.   BIOMATERIALS

Inflammation and wound healing: the role of the macrophage

(2011) Timothy J. Koh et al.   EXPERT REVIEWS IN MOLECULAR MEDICINE

NF- B Signaling Participates in Both RANKL- and IL-4-Induced Macrophage Fusion: Receptor Cross-Talk Leads to Alterations in NF- B Pathways

(2011) M. Yu et al.   JOURNAL OF IMMUNOLOGY

Inflammasome components Asc and caspase-1 mediate biomaterial-induced inflammation and foreign body response

(2011) A. F. Malik et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Parity negatively impacts vaginal mechanical properties and collagen structure in rhesus macaques

(2010) Andrew Feola et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Mesenchymal Stem Cells as Therapeutics

(2010) Biju Parekkadan et al.   Annual Review of Biomedical Engineering

The role of multiple toll-like receptor signalling cascades on interactions between biomedical polymers and dendritic cells

(2010) Behnaz Shokouhi et al.   BIOMATERIALS

Alternative Activation of Macrophages: Mechanism and Functions

(2010) Siamon Gordon et al.   IMMUNITY

Pelvic organ prolapse and incontinence in developing countries: review of prevalence and risk factors

(2010) Godfrey J. A. Walker et al.   INTERNATIONAL UROGYNECOLOGY JOURNAL

Biomaterial topography alters healing in vivo and monocyte/macrophage activation in vitro

(2010) Paige C. S. Bota et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Macrophage plasticity and interaction with lymphocyte subsets: cancer as a paradigm

(2010) Subhra K Biswas et al.   NATURE IMMUNOLOGY

Monocyte and Macrophage Biology: An Overview

(2010) Andrew J. Rees   SEMINARS IN NEPHROLOGY

Isolation and Culture of Epithelial Progenitors and Mesenchymal Stem Cells from Human Endometrium1

(2009) Caroline E. Gargett et al.   BIOLOGY OF REPRODUCTION

Tissue mechanics, animal models, and pelvic organ prolapse: A review

(2009) Steven D. Abramowitch et al.   European Journal of Obstetrics & Gynecology and Reproductive Biology

An estimation of the frequency of surgery for posthysterectomy vault prolapse

(2009) Thomas Aigmueller et al.   INTERNATIONAL UROGYNECOLOGY JOURNAL

Macrophage fusion, giant cell formation, and the foreign body response require matrix metalloproteinase 9

(2009) S. MacLauchlan et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Endosomal damage and TLR2 mediated inflammasome activation by alkane particles in the generation of aseptic osteolysis

(2009) Radhashree Maitra et al.   MOLECULAR IMMUNOLOGY

Molecular mediators of macrophage fusion

(2009) Laura Helming et al.   TRENDS IN CELL BIOLOGY

Molecular mechanisms involved in inflammasome activation

(2009) Clare Bryant et al.   TRENDS IN CELL BIOLOGY

Topographical control of human macrophages by a regularly microstructured polyvinylidene fluoride surface

(2008) Nora E. Paul et al.   BIOMATERIALS

A Perivascular Origin for Mesenchymal Stem Cells in Multiple Human Organs

(2008) Mihaela Crisan et al.   Cell Stem Cell

The foreign body reaction in T-cell-deficient mice

(2008) Analiz Rodriguez et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Paracrine and juxtacrine lymphocyte enhancement of adherent macrophage and foreign body giant cell activation

(2008) David T. Chang et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Animal Models of Female Stress Urinary Incontinence

(2008) Adonis Hijaz et al.   JOURNAL OF UROLOGY

Bone marrow stromal cells attenuate sepsis via prostaglandin E2–dependent reprogramming of host macrophages to increase their interleukin-10 production

(2008) Krisztián Németh et al.   NATURE MEDICINE

Foreign body reaction to biomaterials

(2008) James M. Anderson et al.   SEMINARS IN IMMUNOLOGY

Macrophage activation and polarization

(2007) Fernando Oneissi Martinez   Frontiers in Bioscience-Landmark