Development of hRad51–Cas9 nickase fusions that mediate HDR without double-stranded breaks
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Title
Development of hRad51–Cas9 nickase fusions that mediate HDR without double-stranded breaks
Authors
Keywords
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Journal
Nature Communications
Volume 10, Issue 1, Pages -
Publisher
Springer Science and Business Media LLC
Online
2019-05-17
DOI
10.1038/s41467-019-09983-4
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Note: Only part of the references are listed.- CRISPResso2 provides accurate and rapid genome editing sequence analysis
- (2019) Kendell Clement et al. NATURE BIOTECHNOLOGY
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- (2018) Theodore L. Roth et al. NATURE
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- (2018) Gregory M. Findlay et al. NATURE
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- (2018) Johnny H. Hu et al. NATURE
- Erratum: Repair of double-strand breaks induced by CRISPR–Cas9 leads to large deletions and complex rearrangements
- (2018) Michael Kosicki et al. NATURE BIOTECHNOLOGY
- A high-fidelity Cas9 mutant delivered as a ribonucleoprotein complex enables efficient gene editing in human hematopoietic stem and progenitor cells
- (2018) Christopher A. Vakulskas et al. NATURE MEDICINE
- Predictable and precise template-free CRISPR editing of pathogenic variants
- (2018) Max W. Shen et al. NATURE
- Base editing: precision chemistry on the genome and transcriptome of living cells
- (2018) Holly A. Rees et al. NATURE REVIEWS GENETICS
- Mechanisms of precise genome editing using oligonucleotide donors
- (2017) Yinan Kan et al. GENOME RESEARCH
- Human RAD52 interactions with replication protein A and the RAD51 presynaptic complex
- (2017) Chu Jian Ma et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Programmable base editing of A•T to G•C in genomic DNA without DNA cleavage
- (2017) Nicole M. Gaudelli et al. NATURE
- Inhibition of 53BP1 favors homology-dependent DNA repair and increases CRISPR–Cas9 genome-editing efficiency
- (2017) Marella D Canny et al. NATURE BIOTECHNOLOGY
- Precise and efficient scarless genome editing in stem cells using CORRECT
- (2017) Dylan Kwart et al. Nature Protocols
- Characterization of the interplay between DNA repair and CRISPR/Cas9-induced DNA lesions at an endogenous locus
- (2017) Anne Bothmer et al. Nature Communications
- Improving the DNA specificity and applicability of base editing through protein engineering and protein delivery
- (2017) Holly A. Rees et al. Nature Communications
- Ectopic expression of RAD52 and dn53BP1 improves homology-directed repair during CRISPR–Cas9 genome editing
- (2017) Bruna S. Paulsen et al. Nature Biomedical Engineering
- Continuous evolution of Bacillus thuringiensis toxins overcomes insect resistance
- (2016) Ahmed H. Badran et al. NATURE
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- (2016) Dominik Paquet et al. NATURE
- Programmable editing of a target base in genomic DNA without double-stranded DNA cleavage
- (2016) Alexis C. Komor et al. NATURE
- Analyzing CRISPR genome-editing experiments with CRISPResso
- (2016) Luca Pinello et al. NATURE BIOTECHNOLOGY
- Two Distinct Pathways Support Gene Correction by Single-Stranded Donors at DNA Nicks
- (2016) Luther Davis et al. Cell Reports
- The Tumor-Associated Variant RAD51 G151D Induces a Hyper-Recombination Phenotype
- (2016) Carolyn G. Marsden et al. PLoS Genetics
- Systematic quantification of HDR and NHEJ reveals effects of locus, nuclease, and cell type on genome-editing
- (2016) Yuichiro Miyaoka et al. Scientific Reports
- GUIDE-seq enables genome-wide profiling of off-target cleavage by CRISPR-Cas nucleases
- (2014) Shengdar Q Tsai et al. NATURE BIOTECHNOLOGY
- Efficient genome modification by CRISPR-Cas9 nickase with minimal off-target effects
- (2014) Bin Shen et al. NATURE METHODS
- Homology-directed repair of DNA nicks via pathways distinct from canonical double-strand break repair
- (2014) L. Davis et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The new frontier of genome engineering with CRISPR-Cas9
- (2014) J. A. Doudna et al. SCIENCE
- Characterization of Dual PTEN and p53-Targeting MicroRNAs Identifies MicroRNA-638/Dnm2 as a Two-Hit Oncogenic Locus
- (2014) Yvonne Tay et al. Cell Reports
- Enhanced homology-directed human genome engineering by controlled timing of CRISPR/Cas9 delivery
- (2014) Steven Lin et al. eLife
- Double Nicking by RNA-Guided CRISPR Cas9 for Enhanced Genome Editing Specificity
- (2013) F. Ann Ran et al. CELL
- RNA-Guided Human Genome Engineering via Cas9
- (2013) P. Mali et al. SCIENCE
- Multiplex Genome Engineering Using CRISPR/Cas Systems
- (2013) L. Cong et al. SCIENCE
- RAD51 Mutants Cause Replication Defects and Chromosomal Instability
- (2012) T. M. Kim et al. MOLECULAR AND CELLULAR BIOLOGY
- Playing the End Game: DNA Double-Strand Break Repair Pathway Choice
- (2012) J. Ross Chapman et al. MOLECULAR CELL
- Engineered zinc finger nickases induce homology-directed repair with reduced mutagenic effects
- (2012) Cherie L. Ramirez et al. NUCLEIC ACIDS RESEARCH
- A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity
- (2012) M. Jinek et al. SCIENCE
- Double-Strand Break Repair-Independent Role for BRCA2 in Blocking Stalled Replication Fork Degradation by MRE11
- (2011) Katharina Schlacher et al. CELL
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- (2010) Jie Liu et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Mechanism of Eukaryotic Homologous Recombination
- (2008) Joseph San Filippo et al. Annual Review of Biochemistry
- Single-strand break repair and genetic disease
- (2008) Keith W. Caldecott NATURE REVIEWS GENETICS
- Segmental Duplications Arise from Pol32-Dependent Repair of Broken Forks through Two Alternative Replication-Based Mechanisms
- (2008) Celia Payen et al. PLoS Genetics
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