Organotypic slice cultures of human glioblastoma reveal different susceptibilities to treatments

MGMT, GATA6, CD81, DR4, and CASP8 gene promoter methylation in glioblastoma

(2012) Daina Skiriute et al.   BMC CANCER

Status Quo—Standard-of-Care Medical and Radiation Therapy for Glioblastoma

(2012) Kevin P. Becker et al.   CANCER JOURNAL

MGMT Gene Promoter Methylation as a Potent Prognostic Factor in Glioblastoma Treated With Temozolomide-Based Chemoradiotherapy: A Single-Institution Study

(2012) Young Suk Kim et al.   INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

Three-dimensional Invasion of Human Glioblastoma Cells Remains Unchanged by X-ray and Carbon Ion Irradiation In Vitro

(2012) Iris Eke et al.   INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

Use of personalized molecular biomarkers in the clinical care of adults with glioblastomas

(2012) Matthias Holdhoff et al.   JOURNAL OF NEURO-ONCOLOGY

Overcoming resistance of cancer stem cells

(2012) Diana Pignalosa et al.   LANCET ONCOLOGY

IDH1 mutation is sufficient to establish the glioma hypermethylator phenotype

(2012) Sevin Turcan et al.   NATURE

Prognostic Value of Three Different Methods of MGMT Promoter Methylation Analysis in a Prospective Trial on Newly Diagnosed Glioblastoma

(2012) Arne Christians et al.   PLoS One

The strategy for enhancing temozolomide against malignant glioma

(2012) Mitsutoshi Nakada et al.   Frontiers in Oncology

Inhibition of Collagen XVI Expression Reduces Glioma Cell Invasiveness

(2011) Richard Bauer et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Irradiation of human tumor tissue cultures: optimizing ion radiation therapy

(2011) Felicitas Merz et al.   Future Oncology

Comprehensive Analysis of MGMT Promoter Methylation: Correlation with MGMT Expression and Clinical Response in GBM

(2011) Nameeta Shah et al.   PLoS One

Signaling by the Matrix Proteoglycan Decorin Controls Inflammation and Cancer Through PDCD4 and MicroRNA-21

(2011) R. Merline et al.   Science Signaling

Efficacy of adenovirally expressed soluble TRAIL in human glioma organotypic slice culture and glioma xenografts

(2011) Y Liu et al.   Cell Death & Disease

CD11c-expressing cells reside in the juxtavascular parenchyma and extend processes into the glia limitans of the mouse nervous system

(2010) Carolin Prodinger et al.   ACTA NEUROPATHOLOGICA

Randomized phase II study evaluating a carbon ion boost applied after combined radiochemotherapy with temozolomide versus a proton boost after radiochemotherapy with temozolomide in patients with primary glioblastoma: The CLEOPATRA Trial

(2010) Stephanie E Combs et al.   BMC CANCER

Absence of the MGMT protein as well as methylation of the MGMT promoter predict the sensitivity for temozolomide

(2010) K A van Nifterik et al.   BRITISH JOURNAL OF CANCER

Integrated Genomic Analysis Identifies Clinically Relevant Subtypes of Glioblastoma Characterized by Abnormalities in PDGFRA, IDH1, EGFR, and NF1

(2010) Roel G.W. Verhaak et al.   CANCER CELL

Modeling radiation effects at the tissue level

(2010) M. Müller et al.   EUROPEAN PHYSICAL JOURNAL D

The proteoglycan biglycan regulates expression of the B cell chemoattractant CXCL13 and aggravates murine lupus nephritis

(2010) Kristin Moreth et al.   JOURNAL OF CLINICAL INVESTIGATION

Preclinical model of organotypic culture for pharmacodynamic profiling of human tumors

(2010) V. Vaira et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tissue slice cultures from humans or rodents: a new tool to evaluate biological effects of heavy ions

(2010) Felicitas Merz et al.   RADIATION AND ENVIRONMENTAL BIOPHYSICS

Particle therapy at the Heidelberg Ion Therapy Center (HIT) – Integrated research-driven university-hospital-based radiation oncology service in Heidelberg, Germany

(2010) Stephanie E. Combs et al.   RADIOTHERAPY AND ONCOLOGY

The Use of Temozolomide for the Treatment of Malignant Tumors: Clinical Evidence and Molecular Mechanisms of Action

(2010) Roberto Bei et al.   Recent Patents on Anti-Cancer Drug Discovery

Combinations of genetic mutations in the adult neural stem cell compartment determine brain tumour phenotypes

(2009) Thomas S Jacques et al.   EMBO JOURNAL

Radiobiological evaluation and correlation with the local effect model (LEM) of carbon ion radiation therapy and temozolomide in glioblastoma cell lines

(2009) Stephanie E. Combs et al.   INTERNATIONAL JOURNAL OF RADIATION BIOLOGY

Spatiotemporal analysis of DNA repair using charged particle radiation

(2009) F. Tobias et al.   MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH

Charged particles in radiation oncology

(2009) Marco Durante et al.   Nature Reviews Clinical Oncology

Identification of regions correlating MGMT promoter methylation and gene expression in glioblastomas

(2009) Sibille Everhard et al.   NEURO-ONCOLOGY

Common astrocytic programs during brain development, injury and cancer

(2009) Daniel J. Silver et al.   TRENDS IN NEUROSCIENCES

Collagen XVI expression is upregulated in glioblastomas and promotes tumor cell adhesion

(2008) Volker Senner et al.   FEBS LETTERS

Evaluation of MGMT promoter methylation status and correlation with temozolomide response in orthotopic glioblastoma xenograft model

(2008) Gaspar J. Kitange et al.   JOURNAL OF NEURO-ONCOLOGY

Small interfering RNA–mediated xCT silencing in gliomas inhibits neurodegeneration and alleviates brain edema

(2008) Nicolai E Savaskan et al.   NATURE MEDICINE

Proliferation and cell death of human glioblastoma cells after carbon-ion beam exposure: Morphologic and morphometric analyses

(2008) Takuma Oishi et al.   NEUROPATHOLOGY