Dissecting Colistin Resistance Mechanisms in Extensively Drug-Resistant Acinetobacter baumannii Clinical Isolates

Structure-Function Relationships of the Neisserial EptA Enzyme Responsible for Phosphoethanolamine Decoration of Lipid A: Rationale for Drug Targeting

(2018) Charlene M. Kahler et al.   Frontiers in Microbiology

Structure of a lipid A phosphoethanolamine transferase suggests how conformational changes govern substrate binding

(2017) Anandhi Anandan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Plasmid-Mediatedmcr-1Gene in Colistin-Resistant Clinical Isolates of Klebsiella pneumoniae in France and Laos

(2016) Jean-Marc Rolain et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

A novel genome editing platform for drug resistantAcinetobacter baumanniirevealed an AdeR-unrelated tigecycline resistance mechanism

(2016) Vincent Trebosc et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Emergence of plasmid-mediated colistin resistance mechanism MCR-1 in animals and human beings in China: a microbiological and molecular biological study

(2016) Yi-Yun Liu et al.   LANCET INFECTIOUS DISEASES

A PmrB-Regulated Deacetylase Required for Lipid A Modification and Polymyxin Resistance in Acinetobacter baumannii

(2015) Chui-Yoke Chin et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Polymyxin-Resistant Acinetobacter baumannii: Urgent Action Needed

(2015) J. M. Pogue et al.   CLINICAL INFECTIOUS DISEASES

Lipopolysaccharide loss produces partial colistin dependence and collateral sensitivity to azithromycin, rifampicin and vancomycin in Acinetobacter baumannii

(2015) Meritxell García-Quintanilla et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Phylogenetic and genomic diversity in isolates from the globally distributed Acinetobacter baumannii ST25 lineage

(2015) Jason W. Sahl et al.   Scientific Reports

Antimicrobial resistance: impact on clinical and economic outcomes and the need for new antimicrobials

(2014) Abrar K Thabit et al.   EXPERT OPINION ON PHARMACOTHERAPY

Mechanisms of polymyxin resistance: acquired and intrinsic resistance in bacteria

(2014) Abiola O. Olaitan et al.   Frontiers in Microbiology

Small Molecule Downregulation of PmrAB Reverses Lipid A Modification and Breaks Colistin Resistance

(2013) Tyler L. Harris et al.   ACS Chemical Biology

Biological Cost of Different Mechanisms of Colistin Resistance and Their Impact on Virulence in Acinetobacter baumannii

(2013) Alejandro Beceiro et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

10 x '20 Progress--Development of New Drugs Active Against Gram-Negative Bacilli: An Update From the Infectious Diseases Society of America

(2013) H. W. Boucher et al.   CLINICAL INFECTIOUS DISEASES

Emergence of Colistin-Resistance in Extremely Drug-Resistant Acinetobacter baumannii Containing a Novel pmrCAB Operon During Colistin Therapy of Wound Infections

(2013) Emil Lesho et al.   JOURNAL OF INFECTIOUS DISEASES

Fortifying the barrier: the impact of lipid A remodelling on bacterial pathogenesis

(2013) Brittany D. Needham et al.   NATURE REVIEWS MICROBIOLOGY

New antibiotics for bad bugs: where are we?

(2013) Matteo Bassetti et al.   Annals of Clinical Microbiology and Antimicrobials

Adjuvant strategies for potentiation of antibiotics to overcome antimicrobial resistance

(2012) Michel Pieren et al.   CURRENT OPINION IN PHARMACOLOGY

Global evolution of multidrug-resistant Acinetobacter baumannii clonal lineages

(2012) Raffaele Zarrilli et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

A Truncated AdeS Kinase Protein Generated by ISAba1 Insertion Correlates with Tigecycline Resistance in Acinetobacter baumannii

(2012) Jun-Ren Sun et al.   PLoS One

Insertion Sequence ISAba11Is Involved in Colistin Resistance and Loss of Lipopolysaccharide in Acinetobacter baumannii

(2011) Jennifer H. Moffatt et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

ThepmrCABOperon Mediates Polymyxin Resistance inAcinetobacter baumanniiATCC 17978 and Clinical Isolates through Phosphoethanolamine Modification of Lipid A

(2011) Luis A. Arroyo et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Fusion primer and nested integrated PCR (FPNI-PCR): a new high-efficiency strategy for rapid chromosome walking or flanking sequence cloning

(2011) Zhen Wang et al.   BMC BIOTECHNOLOGY

Multidrug-resistant, extensively drug-resistant and pandrug-resistant bacteria: an international expert proposal for interim standard definitions for acquired resistance

(2011) A.-P. Magiorakos et al.   CLINICAL MICROBIOLOGY AND INFECTION

Correlation between overexpression and amino acid substitution of the PmrAB locus and colistin resistance in Acinetobacter baumannii

(2011) Young Kyoung Park et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Contemporary activity of colistin and polymyxin B against a worldwide collection of Gram-negative pathogens: results from the SENTRY Antimicrobial Surveillance Program (2006-09)

(2011) A. C. Gales et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Hospital-Acquired Infections Due to Gram-Negative Bacteria

(2010) Anton Y. Peleg et al.   NEW ENGLAND JOURNAL OF MEDICINE

The Population Structure of Acinetobacter baumannii: Expanding Multiresistant Clones from an Ancestral Susceptible Genetic Pool

(2010) Laure Diancourt et al.   PLoS One

Resistance to Colistin in Acinetobacter baumannii Associated with Mutations in the PmrAB Two-Component System

(2009) M. D. Adams et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Functional Analysis of Insertion Sequence ISAba1, Responsible for Genomic Plasticity of Acinetobacter baumannii

(2009) P. D. Mugnier et al.   JOURNAL OF BACTERIOLOGY