IFITM3 Clusters on Virus Containing Endosomes and Lysosomes Early in the Influenza A Infection of Human Airway Epithelial Cells

Interferon-induced transmembrane protein 3 blocks fusion of sensitive but not resistant viruses by partitioning into virus-carrying endosomes

(2019) Krishna C. Suddala et al.   PLoS Pathogens

Late Endosomal/Lysosomal Cholesterol Accumulation Is a Host Cell-Protective Mechanism Inhibiting Endosomal Escape of Influenza A Virus

(2018) Alexander Kühnl et al.   mBio

IFITM3 directly engages and shuttles incoming virus particles to lysosomes

(2018) Jennifer S. Spence et al.   Nature Chemical Biology

Population genetics of IFITM3 in Portugal and Central Africa reveals a potential modifier of influenza severity

(2017) Susana David et al.   IMMUNOGENETICS

Evaluation of IFITM3 rs12252 Association With Severe Pediatric Influenza Infection

(2017) Adrienne G. Randolph et al.   JOURNAL OF INFECTIOUS DISEASES

Pilot screening study of targeted genetic polymorphisms for association with seasonal influenza hospital admission

(2017) Tonia C. Carter et al.   JOURNAL OF MEDICAL VIROLOGY

SNP-mediated disruption of CTCF binding at the IFITM3 promoter is associated with risk of severe influenza in humans

(2017) E Kaitlynn Allen et al.   NATURE MEDICINE

Interferon-Induced Transmembrane Protein 3 Inhibits Hantaan Virus Infection, and Its Single Nucleotide Polymorphism rs12252 Influences the Severity of Hemorrhagic Fever with Renal Syndrome

(2017) Zheng Xu-yang et al.   Frontiers in Immunology

IFITM3 and severe influenza virus infection. No evidence of genetic association

(2016) M. López-Rodríguez et al.   EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES

The Interferon-induced Transmembrane Proteins, IFITM1, IFITM2, and IFITM3 Inhibit Hepatitis C Virus Entry

(2015) Sumudu K. Narayana et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Identification of an endocytic signal essential for the antiviral action of IFITM3

(2014) Rui Jia et al.   CELLULAR MICROBIOLOGY

Phosphorylation of the Antiviral Protein Interferon-inducible Transmembrane Protein 3 (IFITM3) Dually Regulates Its Endocytosis and Ubiquitination

(2014) Nicholas M. Chesarino et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Improved vectors and genome-wide libraries for CRISPR screening

(2014) Neville E Sanjana et al.   NATURE METHODS

Correction: Rapid Accumulation of Virulent Rift Valley Fever Virus in Mice from an Attenuated Virus Carrying a Single Nucleotide Substitution in the M RNA

(2014) John C. Morrill et al.   PLoS One

Alteration of Protein Levels during Influenza Virus H1N1 Infection in Host Cells: A Proteomic Survey of Host and Virus Reveals Differential Dynamics

(2014) Susann Kummer et al.   PLoS One

IFITM3 Restricts Influenza A Virus Entry by Blocking the Formation of Fusion Pores following Virus-Endosome Hemifusion

(2014) Tanay M. Desai et al.   PLoS Pathogens

IFITM-Family Proteins: The Cell's First Line of Antiviral Defense

(2014) Charles C. Bailey et al.   Annual Review of Virology

Ellagic acid inhibits human pancreatic cancer growth in Balb c nude mice

(2013) Min Zhao et al.   CANCER LETTERS

The Antiviral Effector IFITM3 Disrupts Intracellular Cholesterol Homeostasis to Block Viral Entry

(2013) Samad Amini-Bavil-Olyaee et al.   Cell Host & Microbe

Emerging roles of recycling endosomes

(2013) T. Taguchi   JOURNAL OF BIOCHEMISTRY

Entry of influenza A virus: host factors and antiviral targets

(2013) T. O. Edinger et al.   JOURNAL OF GENERAL VIROLOGY

IFITM3 and Susceptibility to Respiratory Viral Infections in the Community

(2013) T. C. Mills et al.   JOURNAL OF INFECTIOUS DISEASES

IFITMs Restrict the Replication of Multiple Pathogenic Viruses

(2013) Jill M. Perreira et al.   JOURNAL OF MOLECULAR BIOLOGY

IFITM-2 and IFITM-3 but Not IFITM-1 Restrict Rift Valley Fever Virus

(2013) R. Mudhasani et al.   JOURNAL OF VIROLOGY

The CD225 Domain of IFITM3 Is Required for both IFITM Protein Association and Inhibition of Influenza A Virus and Dengue Virus Replication

(2013) S. P. John et al.   JOURNAL OF VIROLOGY

Genome-Scale CRISPR-Cas9 Knockout Screening in Human Cells

(2013) Ophir Shalem et al.   SCIENCE

IFITM Proteins Restrict Viral Membrane Hemifusion

(2013) Kun Li et al.   PLoS Pathogens

The First Five Seconds in the Life of a Clathrin-Coated Pit

(2012) Emanuele Cocucci et al.   CELL

Rab11 regulates exocytosis of recycling vesicles at the plasma membrane

(2012) Senye Takahashi et al.   JOURNAL OF CELL SCIENCE

Interferon-Inducible Protein Mx1 Inhibits Influenza Virus by Interfering with Functional Viral Ribonucleoprotein Complex Assembly

(2012) J. Verhelst et al.   JOURNAL OF VIROLOGY

IFITM3 restricts the morbidity and mortality associated with influenza

(2012) Aaron R. Everitt et al.   NATURE

Influenza A virus entry into cells lacking sialylated N-glycans

(2012) E. de Vries et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A quantitative proteomic analysis of lung epithelial (A549) cells infected with 2009 pandemic influenza A virus using stable isotope labelling with amino acids in cell culture

(2012) Brian K. Dove et al.   PROTEOMICS

A practical guide to evaluating colocalization in biological microscopy

(2011) Kenneth W. Dunn et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

A Rab11- and Microtubule-Dependent Mechanism for Cytoplasmic Transport of Influenza A Virus Viral RNA

(2011) M. J. Amorim et al.   JOURNAL OF VIROLOGY

Apical Transport of Influenza A Virus Ribonucleoprotein Requires Rab11-positive Recycling Endosome

(2011) Fumitaka Momose et al.   PLoS One

IFITM3 Inhibits Influenza A Virus Infection by Preventing Cytosolic Entry

(2011) Eric M. Feeley et al.   PLoS Pathogens

Distinct Patterns of IFITM-Mediated Restriction of Filoviruses, SARS Coronavirus, and Influenza A Virus

(2011) I-Chueh Huang et al.   PLoS Pathogens

Dissection of the Influenza A Virus Endocytic Routes Reveals Macropinocytosis as an Alternative Entry Pathway

(2011) Erik de Vries et al.   PLoS Pathogens

Quantitative Proteomic Analyses of Influenza Virus-Infected Cultured Human Lung Cells

(2010) Kevin M. Coombs et al.   JOURNAL OF VIROLOGY

Genome-wide RNAi screen identifies human host factors crucial for influenza virus replication

(2010) Alexander Karlas et al.   NATURE

Palmitoylome profiling reveals S-palmitoylation–dependent antiviral activity of IFITM3

(2010) Jacob S Yount et al.   Nature Chemical Biology

Differential infectious entry of human influenza A/NWS/33 virus (H1N1) in mammalian kidney cells

(2010) Flora De Conto et al.   VIRUS RESEARCH

Generation of Recombinant Influenza Virus from Plasmid DNA

(2010) Luis Martínez-Sobrido et al.   Jove-Journal of Visualized Experiments

The Influenza Virus Enigma

(2009) Rachelle Salomon et al.   CELL

A Physical and Regulatory Map of Host-Influenza Interactions Reveals Pathways in H1N1 Infection

(2009) Sagi D. Shapira et al.   CELL

The IFITM Proteins Mediate Cellular Resistance to Influenza A H1N1 Virus, West Nile Virus, and Dengue Virus

(2009) Abraham L. Brass et al.   CELL

Detection of novel swine origin influenza A virus (H1N1) by real-time nucleic acid sequence-based amplification

(2009) Yiyue Ge et al.   JOURNAL OF VIROLOGICAL METHODS

Different Mechanisms of Cell Entry by Human-Pathogenic Old World and New World Arenaviruses

(2008) J. M. Rojek et al.   JOURNAL OF VIROLOGY

Human infection with highly pathogenic H5N1 influenza virus

(2008) Andrea Gambotto et al.   LANCET

The biology of influenza viruses

(2008) Nicole M. Bouvier et al.   VACCINE